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Search Results - jun+yao
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Endothelium-Specific Laminin Reporter Mouse Line Laminin-mCherry/eGFP+/–; Cdh5-CreER+/– Mouse Line
Advantages Enables endothelial-specific labeling of laminin-γ1 in vivo. Tamoxifen-inducible system allows temporal control of recombination. Dual-color fluorescence distinguishes target cell-derived laminin from other cell-derived laminin. Co-localization with laminin-γ1 antibody confirms biological fidelity. Facilitates mapping...
Published: 10/9/2025
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Inventor(s):
Yao Yao
Keywords(s):
Animal Models
,
Research Tools
Category(s):
Technology Classifications > Research Tools/Copyright > Animal Models
Novel Laminin Reporter Mouse Line for in vivo Imaging and Laminin Biology Research (Laminin-mCherry/eGFP+/-) Pre-Cre
Advantages First-ever dual-color laminin reporter mouse line. Enables visualization of laminin-γ1 expression in vivo with high fidelity. mCherry signal replicates endogenous laminin distribution without Cre activation. No background eGFP signal ensures clean baseline imaging. Targets the widely expressed γ1 subunit, enhancing...
Published: 10/9/2025
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Inventor(s):
Yao Yao
Keywords(s):
Animal Models
,
Neuroscience
,
Research Tools
Category(s):
Technology Classifications > Research Tools/Copyright > Animal Models
Electric power generation from ambient moisture using microbial nanowires
PRODUCT OPPORTUNITIES • Sustainable electronics • Various applications requiring electric power PRODUCT OPPORTUNITIES COMPETITIVE ADVANTAGES • Producing electricity from air • Constant availability agnostic of time and location • Sustainability TECHNOLOGY DESCRIPTION This invention demonstrates...
Published: 6/12/2025
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Inventor(s):
Jun Yao
,
Derek Lovley
,
Xiaomeng Liu
Keywords(s):
Category(s):
Clean Energy
,
Devices
,
Electronics
,
Engineering
,
Environmental
High-throughput RNA sequencing technology for comprehensive transcriptome profiling and biomarker identification in inflammatory breast cancer
The technology utilizes TGIRT-seq, a high-throughput RNA sequencing method, to identify potential biomarkers for inflammatory breast cancer by profiling coding and non-coding RNAs in tumor and blood samples, aiding in diagnosis and disease monitoring. Background Inflammatory breast cancer (IBC) is recognized as the most aggressive form of breast cancer,...
Published: 10/22/2024
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Inventor(s):
Alan Lambowitz
,
Dennis Wylie
,
Lauren Ehrlich
,
Elizabeth Kiddie
,
Hengyi Xu
,
Jun Yao
,
Naoto Ueno
,
Xiaoping Wang
Keywords(s):
Category(s):
Life sciences > Diagnostic
Full-length excised intron RNA sequencing and analysis for disease diagnosis
Problem RNA molecules that are newly transcribed from the corresponding DNA sequence contain intron and exon sequences. Introns are removed by a process called RNA splicing, where the introns are removed and the exons are ligated to form the mature messenger RNA (mRNA) and full-length excised intron RNAs (FLEXIRs). The majority of FLEXIRs and the genes...
Published: 8/15/2024
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Inventor(s):
Alan Lambowitz
,
Hengyi Xu
,
Douglas Wu
,
Jun Yao
Keywords(s):
Category(s):
Life sciences > Diagnostic
,
Life sciences > Research tools > Tool/assay/screening platform