Search Results - yao+yao

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Tumor-pH–Triggered Doxorubicin Prodrug with On-Demand Shelf-Stable Precursor
This invention introduces a small-molecule doxorubicin prodrug that remains inert in blood and rapidly activates in the mildly acidic tumor microenvironment. Featuring a shelf-stable maleimide pre-prodrug that converts on demand to the ultra-acid-labile DMA form, it enables targeted chemotherapy with improved selectivity, scalable synthesis, and reduced...
Published: 10/10/2025   |   Inventor(s): Ming An, Lan Yao, Vladyslav Nazarenko
Keywords(s): Technologies
Category(s): Campus > Binghamton University
Endothelium-Specific Laminin Reporter Mouse Line Laminin-mCherry/eGFP+/–; Cdh5-CreER+/– Mouse Line
Advantages Enables endothelial-specific labeling of laminin-γ1 in vivo. Tamoxifen-inducible system allows temporal control of recombination. Dual-color fluorescence distinguishes target cell-derived laminin from other cell-derived laminin. Co-localization with laminin-γ1 antibody confirms biological fidelity. Facilitates mapping...
Published: 10/9/2025   |   Inventor(s): Yao Yao
Keywords(s): Animal Models, Research Tools
Category(s): Technology Classifications > Research Tools/Copyright > Animal Models
Novel Laminin Reporter Mouse Line for in vivo Imaging and Laminin Biology Research (Laminin-mCherry/eGFP+/-) Pre-Cre
Advantages First-ever dual-color laminin reporter mouse line. Enables visualization of laminin-γ1 expression in vivo with high fidelity. mCherry signal replicates endogenous laminin distribution without Cre activation. No background eGFP signal ensures clean baseline imaging. Targets the widely expressed γ1 subunit, enhancing...
Published: 10/9/2025   |   Inventor(s): Yao Yao
Keywords(s): Animal Models, Neuroscience, Research Tools
Category(s): Technology Classifications > Research Tools/Copyright > Animal Models
Energy Efficient Steep Slope Cold Electron DIRAC Transistor
Graphene-enabled Dirac-source "cold" electron transistor breaks the sub-60 mV/decade threshold and achieves current density over 1µA/µm Background: Power dissipation and energy efficiency in electronics are huge barriers facing the explosive growth of artificial intelligence (AI) and high-performance computing (HPC). Metal-oxide-semiconductor...
Published: 10/2/2025   |   Inventor(s): Huamin Li, Fei Yao
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Energy Conservation, Technology Classifications > Nanotechnology, Technology Classifications > Electronics
SECURE BIOMETRIC RECOGNITION USING EFFICIENT NEURAL NETWORKS
Value proposition Face Recognition (FR) has become integral to identity management in many practical applications, from unlocking personal devices to facilitating law enforcement and accessing financial services. These systems process sensitive biometric data that, if compromised, can lead to privacy invasions, identity theft, and unauthorized surveillance....
Published: 9/15/2025   |   Inventor(s): Vishnu Boddeti, Wei Ao
Keywords(s):  
Category(s): Computer Software, Informatics, Data Processing/Analysis
Continuous Monitoring with Compact System Representations to Detect Advanced Persistent Threats
THE CHALLENGE The growing danger of Advanced Persistent Threats (APTs), stealthy, multi-stage cyberattacks, poses a major challenge to detect subtle malicious behaviors hidden within massive volumes of system audit logs without overwhelming their infrastructure. Traditional defenses rely on constructing detailed provenance graphs to trace system activity,...
Published: 10/9/2025   |   Inventor(s): Danfeng Yao, Wenjia Song
Keywords(s):  
Category(s): Technology Classifications > Security
Exceptional Point Optomechanical Infrared Thermal Imaging Detector (EPOPTIM)
Background Mid to long-wave infrared detectors capture and interpret infrared radiation emitted by objects, and convert it into additional data. These detectors have wide ranging applications including gas sensing, thermal imaging, environmental monitoring, and defense applications. Typically, these detectors use micro- or nano-scale microwave-frequency...
Published: 7/24/2025   |   Inventor(s): Yu Yao, Linbo Shao, Yizheng Zhu
Keywords(s):  
Category(s): Physical Science, Imaging, Environmental, Applied Technologies
Real-Time Program-Specific Log Consolidation for Intrusion Detection
Advantages Reduces logs 219× for efficient data storage Performs real-time analysis with zero offline cost Minimizes memory use through subject activity consolidation Maintains high detection accuracy with low alert fatigue Summary Enterprises today are increasingly targeted by Advanced Persistent Threats (APTs), stealthy, long-term attacks...
Published: 7/18/2025   |   Inventor(s): Yao Liu, Xiao Han, Zhuo Lu
Keywords(s): Computer Science, Cybersecurity
Category(s): Technology Classifications > Computer Science > C/S Cybersecurity, Technology Classifications > Computer Science > Algorithms, Technology Classifications > Computer Science > Computers Software & Information Technology, Technology Classifications > Computer Science > Datasets
Electric power generation from ambient moisture using microbial nanowires
PRODUCT OPPORTUNITIES • Sustainable electronics • Various applications requiring electric power PRODUCT OPPORTUNITIES COMPETITIVE ADVANTAGES • Producing electricity from air • Constant availability agnostic of time and location • Sustainability TECHNOLOGY DESCRIPTION This invention demonstrates...
Published: 6/12/2025   |   Inventor(s): Jun Yao, Derek Lovley, Xiaomeng Liu
Keywords(s):  
Category(s): Clean Energy, Devices, Electronics, Engineering, Environmental
Neutrophil Subsets for the Treatment of Cancer
THE CHALLENGE Developing a cancer immunotherapy platform that can effectively and safely leverage the complex role of neutrophils—an abundant, yet highly variable, type of innate immune cell continues to prove challenging. Unlike current therapies that primarily target the adaptive immune system, an approach that must navigate the dual nature...
Published: 6/25/2025   |   Inventor(s): Liwu Li, Yao Zhang
Keywords(s):  
Category(s): Technology Classifications > Biomedical, Technology Classifications > Biotechnology, Technology Classifications > Pharmacology and Therapeutics
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