Search Results - infectious+disease

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Covid Prevention and Treatment Using an Integrin Inhibitor
Overview Although several highly effective vaccines against COVID-19 have been developed, the disease remains a threat to public health. We have invented a method of preventing or treating COVID-19 through administration of an integrin inhibitor such as GLPG-0187. Market Opportunity Although several highly effective vaccines against COVID-19 have...
Published: 6/7/2023   |   Inventor(s): Wafik El-Deiry, Kelsey Huntington, Lindsey Carlsen, Olin Liang, Matthias Piesche
Keywords(s):  
Category(s): Therapeutics, Infectious Disease
Ultra-Specific and Ultra-Sensitive Platform for Highly-Reliable and High-Precision SARS-CoV-2 Detection
Background:The technology described is based on the use of two unique sets of detection molecules that are specific to a protein contained in the viral shell of SARS CoV-2 and Covid-19 that is unique from other known common cold causing coronaviruses. The proposed system uses two different fluorescent probes for two different regions of the viral shell...
Published: 10/26/2023   |   Inventor(s): Rodrigo Fernandez-Valdivia
Keywords(s): Coronavirus, COVID-19, Diagnostic, Virus
Category(s): Diagnostic, Biomedical, Medical, Diseases, Infectious disease
SALT-FORMULATED VALPROATE AS A TOPICAL ANTI-FUNGAL TREATMENT
In 2018, the global antifungal drugs market size was valued at USD 11.6 billion. Generally speaking, 54.3% of sales are prescription and 45.7% is over-the counter OTC/Alternative. It is anticipated that the OTC/Alternative portion of the global antifungal market will continue to grow. Science is indicating that both the number of systemic infections...
Published: 1/21/2022   |   Inventor(s): Miriam Greenberg, Rania Deranieh
Keywords(s):  
Category(s): Diseases, Infectious disease, Life Science, Small molecule, Pharmaceuticals
Activated T Cells and Activated T Cells Armed with BiSpecific Antibodies Directed at Cancer Antigens are Poor Responders to Alloantigens May Help Engraftment and Improve Anti-Tumor Effects
BackgroundThe treatment of hematologic malignancies with allogeneic stem cell transplant is limited by the numbers of allogeneic donors. Umbilical cord blood stem transplants have been an important alternative source of hematopoietic stem cells. However, failure or delayed engraftment remains the critical barrier to the success of the transplants....
Published: 3/2/2022   |   Inventor(s): Lawrence Lum
Keywords(s): Anti-cancer
Category(s): Life Science, Therapeutics, Diseases, Infectious disease
Use of Raman Spectroscopy to Decrease Time to Identify the Species of Candida and bacterial Growth in Cultures.
Use of Raman Spectroscopy to Decrease Time to Identify MRSA Verses MSSA and the Subspecies of Candida and bacterial Growth in Cultures WSU Tech#: 15-1270 Technology Summary: New Technology for the identification of MRSA versus MSSA and sub-species for both bacterial staph Aureus (SA) and Candida in one package, using Raman Spectroscopy. This work...
Published: 2/9/2022   |   Inventor(s): Nitin Chouthai
Keywords(s):  
Category(s): Imaging, Drug Discovery, Infectious disease, Instrumentation, Software
Vaginal microbiome snapshot (VMS)
Vaginal Microbiome Sanpshot; a Method for Diagnosing Bacterial Vaginosis and Other Vaginal Disorders WSU Tech#: 13-1141 Technology Summary: Bacterial vaginosis (BV) is a disease of the vagina caused by an imbalance of naturally occurring bacterial flora and is often confused with yeast infection (candidiasis) or infection with Trichomonas vaginalis...
Published: 10/27/2020   |   Inventor(s): Robert Akins, Jack Sobel
Keywords(s):  
Category(s): Assays, Biomedical, Diagnostic, Diagnostics, Infectious disease
Antibacterial activity of natural compounds and their synthetic analogue: A potential new antibiotic with potent activity against multiple drug resistant bacterial pathogens
Our researchers have developed novel compounds that are potential new anti-infective therapeutics useful for treatment against the deadly bacteria MRSA (methicillin-resistant Staphylococcus aureus), VRE (vancomycin-resistant Enterococcus faecium), and several other well-known common infectious agents.Background & Unmet Need:Before antibiotics became...
Published: 8/9/2022   |   Inventor(s): Hossein Salimnia, Fazlul Sarkar, Subhash Padhye, Bernhard Biersack
Keywords(s): Analog or Analogue, Antibiotics, Anti-infective, Anti-microbial, Disease
Category(s): Biologicals, Diseases, Infectious disease, Life Science, Therapeutics
Using Flagellin to Prevent and to Treat Inflammation Associated Gram Negative Bacterial Infection
This technology provides a new method for treating inflammatory diseases by using a Gram negative bacterial component that results in increased tolerance and immunity. Background & Unmet Need: Despite advances of modern medicine, bacterial sepsis remains one of the major threats to human health worldwide. In the US alone, it affects approximately...
Published: 6/7/2022   |   Inventor(s): Fu-Shin Yu, Ashok Kumar, Jing Zhang, Linda Hazlett
Keywords(s): Anti-microbial, Asthma
Category(s): Therapeutics, Diseases, Life Science, Infectious disease
Mannich Bases of Conjugated Styryl Ketones
Detailed Description Human infectious diseases caused by fungi have increased markedly during the past 10 years due mainly to advances in medical care that involve prolonged immune suppression increased use of cytotoxic drugs in cancer chemotherapy and the advent of AIDS. As a result organisms such as Candida albicans have become opportunistic...
Published: 2/27/2022   |   Inventor(s): Jonathan Dimmock, Elias Manavathu
Keywords(s): Anti-infective, Therapeutics
Category(s): Therapeutics, Life Science, Infectious disease