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Search Results - floxed
3
Results
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Published Date
Updated Date
Title
ID
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Mice with a
Floxed
Allele of the alpha Subunit of the Heterotrimeric G Protein Go or Gi2
Heterotrimeric G proteins couple signals between GPCRs (G protein coupled receptors) and effectors such as adenylyl cyclase, phospholipase C and ion channels. Among the G proteins are Go and Gi2. Go is highly expressed in the brain and some endocrine tissues while Gi2 is widely expressed throughout the body. The ß?-subunits of Go interact with ion...
Published: 7/25/2024
|
Inventor(s):
Joel Abramowitz
,
Lutz Birnbaumer
Keywords(s):
?
,
ALLELE
,
ALPHA
,
Floxed
,
G
,
Gi2
,
Go
,
Heterotrimeric
,
Listed LPM Tong as of 4/15/2015
,
Mice
,
Post LPM Assignment Set 20150420
,
Pre LPM working set 20150418
,
Protein
,
SUBUNIT
,
WBXXXX
,
WIXXXX
,
WJXXXX
,
WKXXXX
,
XEXXXX
,
YAXXXX
Category(s):
Collaboration Sought > Licensing
,
Application > Therapeutics
,
Application > Diagnostics
,
Application > Research Materials
TRPC Knockout (KO) Mice and Mice with a
Floxed
Allele of TRPC Ion Channel Genes
TRPCs (Canonical Transient Receptor Potential Channels) are a group of non-selective cation channels that allow sodium and calcium into cells. There are seven different genes in mice that code TRPCs. The in vivo roles played by TRPCs as a whole are poorly understood and very little is known about the in vivo roles played by individual TRPCs nor the...
Published: 7/25/2024
|
Inventor(s):
Joel Abramowitz
,
Lutz Birnbaumer
Keywords(s):
ALLELE
,
CHANNEL
,
Floxed
,
Gene
,
ION
,
Knockout
,
Listed LPM Tong as of 4/15/2015
,
Mice
,
Post LPM Assignment Set 20150420
,
Pre LPM working set 20150418
,
TRPC3
,
TRPC5
,
TRPC7
,
WBXXXX
,
WIXXXX
,
WJXXXX
,
WKXXXX
,
XEXXXX
,
YAXXXX
Category(s):
Collaboration Sought > Licensing
,
Application > Therapeutics
,
Application > Research Materials
,
Application > Diagnostics
Mice with a Conditional LoxP-Flanked Glucosylceramide Synthase Allele Controlling Glycosphingolipid Synthesis
Glycosphingolipids are organizational building blocks of plasma membranes that participate in key cellular functions, such as signaling and cell-to-cell interactions. Glucosylceramide synthase - encoded by the Ugcg gene - controls the first committed step in the major pathway of glycosphingolipid synthesis. Global disruption of the Ugcg gene in mice...
Published: 7/25/2024
|
Inventor(s):
Richard Proia
Keywords(s):
ACXXXX
,
AXXXXX
,
Carrying
,
ESTABLISHMENT
,
Floxed
,
Gene
,
glucosylceramide
,
Mice
,
RXXXXX
,
SYNTHASE
,
Ugcg
Category(s):
Collaboration Sought > Collaboration
,
Collaboration Sought > Licensing
,
Collaboration Sought > Materials Available
,
Application > Research Materials