Inteum Company
Links
seedsprint
Visible Legacy
RSS
News & Resources
Inteum Company News
Inteum Library
Subscribe
Search Results - g
16990
Results
Sort By:
Published Date
Updated Date
Title
ID
Descending
Ascending
Methods To
G
enerate Constrained Fluorinated Macrocycles (UCLA Case No. 2023-139)
UCLA researchers from the Department of Chemistry and Biochemistry have developed a novel method to
g
enerate fluorinated polycycles, which may be used for downstream drug discovery and development. BACKGROUND: A significant amount of research in the field of organic chemistry centers around generating increasingly complex molecules that cyclize, forming...
Published: 5/30/2025
|
Inventor(s):
Patrick Harran
Keywords(s):
Dru
g
Discovery
Category(s):
Chemical > Synthesis
,
Chemical > Catalysts
Modified Hyaluronic Acid Hydro
g
els Containing Hyaluronidase for the Time‐Controlled and Targeted Release of anti-CTLA-4 and other Therapeutic Antibodies (UCLA Case No. 2016-526)
UCLA researchers from the Department of Medicine have developed a novel therapeutic platform for the administration of low-dose Cytotoxic T-lymphocyte Associated Protein 4 (CTLA-4) antibody for cancer immunotherapy that syner
g
izes with conventional PD-1 therapy while sparing systemic autoimmune toxicity. BACKGROUND: Immune checkpoint inhibitor (CPI)...
Published: 5/30/2025
|
Inventor(s):
Michael Roth
,
Airi Harui
Keywords(s):
Cancer Immunotherapy
,
Immunotherapy
Category(s):
Platforms > Dru
g
Delivery
,
Therapeutics > Immunolo
g
y And Immunotherapy
,
Therapeutics > Oncolo
g
y
A desi
g
n to manufacture polyamide reverse osmosis membrane using molecular layer-by-layer deposition
Thin-film composite polyamide membranes, are the basis for modern commercial reverse osmosis (RO) membranes. These membranes are created throu
g
h interfacial polymerization (IP) involving a trifunctional acid chloride (e.g., trimesoyl chloride, TMC, dissolved in an organic solvent) and a difunctional amine (e.g., m-phenylenediamine, MPD, dissolved in...
Published: 5/30/2025
|
Inventor(s):
Samarpan Deb Majumder
,
Xiton
g
Liu
Keywords(s):
Category(s):
Technolo
g
y Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment
,
Technolo
g
y Classifications > Industrial or Consumer Tech > Industrial Manufacturing
Robot-Aided System And Method For Dia
g
nosis Of Autism Spectrum Disorder
Sensory abnormalities are reported to be central to autistic experience. The symptoms include hyposensitivity, hypersensitivity, multichannel receptivity, processin
g
difficulties and sensory overload. Given the intensive and cumbersome nature of current methods of diagnosis, there is a need of behavior-based approach to identify the children at risk...
Published: 5/30/2025
|
Inventor(s):
Chun
g
Hyuk Park
,
Hifza Javed
Keywords(s):
Category(s):
Technolo
g
y Classifications > Diagnostics
,
Technolo
g
y Classifications > Medical Devices > Therapeutic Devices
Tampa Neuromappin
g
Depth Electrode
Advanta
g
es Combines recording and stimulation in a single device Reduces brain penetration and surgery time Lowers risk of hemorrhage, infection, and brain shift Enables precise brain mapping and real-time stimulation Summary Deep Brain Stimulation (DBS) helps patients with movement disorders like Parkinson’s disease by sending electrical...
Published: 5/30/2025
|
Inventor(s):
Oliver Flouty
,
Yarema Bezchlibnyk
,
Vishal Bharmauria
,
Nour Shaheen
,
Brian Dalm
,
Can Sarica
,
Matthew Howard
,
Hiroto Kawasaki
,
Mario Zanaty
,
Alex
G
reen
,
Andres Lozano
Keywords(s):
Category(s):
Technolo
g
y Classifications > Medical > Neuroscience
En
g
ineering Asymmetrically Glycosylated IgG Antibodies
Application A novel method to develop asymmetrically
g
lycosylated therapeutic monoclonal IgG antibodies for preventing and treating diseases like cancer, infectious diseases, and autoimmune disorders. Key Benefits Different IgG antibody glycoforms can be produced, each with its unique effector functions and biological and therapeutic effects. Potential...
Published: 5/30/2025
|
Inventor(s):
Eric J. Sundber
g
,
Jonathan Du
,
Tala Azzam
Keywords(s):
Antibodies
,
Immunolo
g
y and Inflammation Treatments
,
Microbiolo
g
y and Infectious Disease Treatments
,
Oncolo
g
y Treatments
Category(s):
TechPub Al
g
olia > Therapeutics
Companion Dia
g
nostic for Immunomodulatory Repair Treatments
This technolo
g
y is a diagnostic tool designed to help match patients to specific drugs or therapies to treat chronic ischemic heart failure. The platform focuses on immune cells called macrophages, which play a crucial role in the body's response to injury and disease. By promoting a specific type of macrophage known to aid healing, this system...
Published: 5/30/2025
|
Inventor(s):
Steven
G
oldman
,
Daniel Benson
,
Adrian
G
rijalva
,
Jordan Fink
,
Jordan Lancaster
,
Jennifer Koevary
,
Simar Sin
g
h
Keywords(s):
Category(s):
Technolo
g
y Classifications > Life Sciences > Diagnostics
,
Technolo
g
y Classifications > Research Tools > Screening assays
,
Technolo
g
y Classifications > Healthcare Portfolios > Heart and Vascular
RNA Bindin
g
Motif 3 (RBM3) Overexpressing Transgenic Mouse
Advanta
g
es • RBM3 upregulation reverses multiple tau phosphorylations post-TBI • Novel RBM3 Overexpressing Transgenic Mouse Model allows researchers to study the effects of RBM3 activation on tissue function, brain function, and brain injury Summary Traumatic brain injury (TBI) not only causes immediate neuronal damage but also...
Published: 5/30/2025
|
Inventor(s):
Travis Jackson
Keywords(s):
Animal Models
,
Neuroscience
Category(s):
Technolo
g
y Classifications > Research Tools/Copyright > Animal Models
,
Technolo
g
y Classifications > Medical > Neuroscience
,
Technolo
g
y Classifications > Medical > Biotechnology
Method for Co-Localizin
g
Two Proteins on the Inside of the Cell Membrane in Yeast
Advanta
g
es Localization of protein interactions at the cell membrane offers a more physiologically relevant model Improved screening by minimizing off-target interactions Broadly applicable and accessible tools Summary Protein-protein interactions involving membrane proteins are notoriously difficult to study under physiologically relevant conditions....
Published: 5/30/2025
|
Inventor(s):
Lawrence Stern
,
Michael Nelson
Keywords(s):
Dru
g
Discovery
Category(s):
Technolo
g
y Classifications > Medical > Cell & Tissue Engineering
,
Technolo
g
y Classifications > Medical > Medical Diagnostics
,
Technolo
g
y Classifications > Medical > Biomaterials
Trans
g
enic Foxc2-tdTomato Overexpressing Mouse Model for Study and Screening of Lymphatic Valve Development
Advanta
g
es Tissue specific Foxc2 expression with integrated tdTomato fluorescent reporter enables precise spatiotemporal visualization Enables monitoring of lymphatic valve development 1:1 co-expression of Foxc2 and tdTomato, overcoming expression variability characteristic associated with of IRES-based or viral delivery systems Single-vector...
Published: 5/30/2025
|
Inventor(s):
Joshua Scallan
Keywords(s):
Animal Models
Category(s):
Technolo
g
y Classifications > Research Tools/Copyright > Animal Models
1
2
3
4
5
6
7
8
9
10
...