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High-Throughput, Multi-Well Spatiotemporal Illumination Microscope (UCLA Case No. 2024-100)
UCLA researchers from the Department in Neurology have developed a spatiotemporal illumination microscope system. The system includes a multi-well plate configured to receive live cells and a DMD (Digital Micromirror Device) configured to deliver targeted illumination to selectively illuminate a plurality of the wells. The system further includes a...
Published: 9/15/2025   |   Inventor(s): Daniel Aharoni
Keywords(s):  
Category(s): Life Science Research Tools > Microscopy And Imaging
Metal Chalcogenides for Pseudocapacitive Applications (Case No. 2016-178)
Summary Researchers at UCLA have developed nanocrystalline, defect-rich metal dichalcogenide materials with expanded interlayer spacing that enable pseudocapacitive charge storage for Li⁺, Na⁺, Mg²⁺, and Ca²⁺ ion systems. These materials deliver high rate performance, suppress deleterious phase transformations, and enable fast charging/discharging...
Published: 9/15/2025   |   Inventor(s): Sarah Tolbert, Bruce Dunn, John Cook, Hyungseok Kim
Keywords(s):  
Category(s): Materials, Materials > Functional Materials, Materials > Nanotechnology, Materials > Metals, Energy & Environment, Energy & Environment > Energy Efficiency, Energy & Environment > Energy Storage > Batteries, Energy & Environment > Energy Storage
TYRP-1 Chimeric Antigen Receptor to Treat Melanoma (UCLA Case No. 2020-106)
UCLA researchers in the Departments of Surgical Oncology and Microbiology, Immunology, & Molecular Genetics. have developed a CAR-T therapy that targets TYRP-1 for the treatment of melanoma. BACKGROUND: Immune checkpoint blockade (ICB) is a rapidly emerging immunotherapy approach that uses patients’ immune cells to treat cancer. In contrast...
Published: 9/15/2025   |   Inventor(s): Cristina Puig Saus, Antoni Ribas, Yvonne Chen
Keywords(s): Gene Therapy, Hematology, Immunotherapy, Research Methods
Category(s): Therapeutics > Hematology
Pioneering Cell-Based Solutions for Vascular Aging
This invention is a mechanism-based cell therapy for treating aortic stiffening, particularly in cases of old hypertension patients that do not respond to current treatments. It is also intended to help prevent cardiovascular disease and promote healthy aging in older populations. Background: Aortic stiffening is a critical age-related risk factor...
Published: 9/15/2025   |   Inventor(s): Hongyu Qiu, Liwu Li
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Life Sciences > Therapeutics
Low-Latency Decoder for the Bahl, Cocke, Jelinek, Raviv Algorithm (Case No. 2025-114)
Summary UCLA researchers have developed a low-latency, high-throughput GPU-based implementation of the BCJR (Bahl-Cocke-Jelinek-Raviv) algorithm for decoding the CCSDS Serially-Concatenated Convolutionally-Coded Pulse-Position Modulation (SCPPM) code. The innovation reduces decoding latency from linear in the number of trellis stages to logarithmic...
Published: 9/15/2025   |   Inventor(s): Richard Wesel, Amaael Antonini, Egor Glukhov, Dariush Divsalar
Keywords(s):  
Category(s): Software & Algorithms, Software & Algorithms > Security & Privacy, Software & Algorithms > Communication & Networking, Mechanical, Mechanical > Aeronautics & Aerospace
Bottom-Up Low-Temperature Synthesis of Graphene Interconnects for GAAFETs
This invention introduces a method for creating ultra-thin, highly conductive carbon-based wiring, called graphene interconnects, on metal surfaces at low temperatures. These interconnects are intended to replace traditional copper wiring used in advanced semiconductor devices, particularly those based on Gate-All-Around Field-Effect Transistors (GAAFETs)....
Published: 9/15/2025   |   Inventor(s): Zafer Mutlu
Keywords(s):  
Category(s): Technology Classifications > Engineering & Physical Sciences > Semiconductors, Technology Classifications > Engineering & Physical Sciences > MEMS & Nanotechnology
Development of Single-Crystalline 2D Gate Dielectrics for GAAFET Technologies
This invention introduces a new class of materials designed to improve how next-generation chips manage electrical signals at extremely small scales, particularly those based on Gate-All Around Field-Effect Transistors (GAAFETs). These single-crystalline 2D dielectrics offer high dielectric strength and stability, helping to reduce power loss and signal...
Published: 9/15/2025   |   Inventor(s): Zafer Mutlu
Keywords(s):  
Category(s): Technology Classifications > Engineering & Physical Sciences > Communications & Networking, Technology Classifications > Engineering & Physical Sciences > Electronics
Altering Legume Phenotypes with Seedborne Microbes for Nutrition and Resilience of Pulses as Climate-Proof Crops
This technology leverages seed-associated bacterial endophytes to enhance the traits of tepary beans and other legumes. The inventors developed a novel workflow to isolate and screen beneficial microbes from seeds, allowing for predictive assessment of plant growth benefits such as phosphate solubilization, ammonium production, and siderophore activity....
Published: 9/15/2025   |   Inventor(s): Anne Arnold, Caroline Maro, William Duke Pauli, Erica Cortez, Jimaree Legins, Michael Dake
Keywords(s):  
Category(s): Technology Classifications > Agriculture & Horticulture > Crop Improvement
Ultrafast Doping in Polycrystalline Chalcogenides
Background Cadmium telluride (CdTe) photovoltaic technology is considered one of the most successful commercial thin film solar cell technologies, boasting a power conversion efficiency of approximately 23%. Despite this achievement, the current power conversion efficiency for CdTe modules is still far from the theoretical power conversion efficiency...
Published: 9/15/2025   |   Inventor(s): Feng Yan
Keywords(s): PS-Advanced Materials and Nanotechnology, PS-Energy and Power, PS-Environmental, Solar cells, Solar Energy, Thin Films
Category(s): Advanced Materials/Nanotechnology, Alternative Energy, Energy & Power, Environmental, Physical Science
Nanocomposite Scintillators (Case No. 2024-203)
Summary UCLA researchers have developed a nanocomposite scintillator material combining high-atomic-number (high-Z) nanoparticles embedded in a plastic (polymer) matrix, with tunable nanoparticle loading, that delivers higher light output and ultrafast emission (nanosecond-scale) while maintaining low background radiation and environmental stability,...
Published: 9/15/2025   |   Inventor(s): Qibing Pei, Ziqing Han, Isabelle Winardi
Keywords(s):  
Category(s): Electrical, Electrical > Electronics & Semiconductors, Materials, Materials > Nanotechnology, Materials > Functional Materials, Optics & Photonics, Optics & Photonics > Spectroscopy
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