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17515
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ID
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nsP2 Inhibitors: Tar
g
eting the Alphavirus nsP2 Protease
This invention relates to antiviral compounds tar
g
eting the alphavirus nsP2 protease, pharmaceutical compositions, and methods of use for the prevention, treatment, or mitigation of the Chikungunya virus. This compound selectively interferes with the essential proteolytic processing activity of nsP2, a critical step in the viral life cycle. By blocking...
Published: 4/29/2026
|
Updated: 4/29/2026
|
Inventor(s):
Hon
g
min Li
,
Rui Xion
g
,
Subodh Samrat
,
Malla Reddy
G
annarapu
,
Ran Zhan
g
,
Ke Chen
,
Men
g
jiao Ma
,
Omar Alejandro Lozano Ramos
,
Divakar Indukuri
,
Renu Bhardwaj
Keywords(s):
Category(s):
Technolo
g
y Classifications > Healthcare Portfolios > Infectious Diseases
,
Technolo
g
y Classifications > Life Sciences > Therapeutics
,
Technolo
g
y Classifications > Life Sciences > Small Molecules
Northwestern Startup: Actinia
Founded: 2020 Northwestern Inventor: Mercouri Kanatzidis Weinber
g
College of Arts and Sciences Department of Chemistry Actinia’s mission is to increase the resolution and decrease the dose used in radiological imaging techniques such as SPECT, CT, and even plain X-rays. Actinia develops cutting-edge radiation detector materials...
Published: 4/29/2026
|
Updated: 4/29/2026
|
Inventor(s):
Keywords(s):
Startup with Northwestern IP
Category(s):
Physical Sciences > Ener
g
y & Sustainability
,
Life Sciences > Healthcare Devices, Tools & IT
,
Life Sciences > Healthcare Devices, Tools & IT > Radiolo
g
y
,
Physical Sciences > En
g
ineering & Technology
,
Physical Sciences > Materials and Industrial Processes
Dual-Action Inhibition Strate
g
y for KRAS and LKB1 Mutant NSCLC
NU 2023-113 INVENTORS Lillian Eichner (Feinber
g
School of Medicine, Department of Biochemistry and Molecular Genetics)* Reuben Shaw (Salk Institute) SHORT DESCRIPTION A dual drug combination to target KRAS and LKB1 mutant non–small cell lung cancer that results in superior efficacy by enhancing T cell recruitment and reducing tumor burden. BACKGROUND Lung...
Published: 4/29/2026
|
Updated: 4/29/2026
|
Inventor(s):
Reuben Shaw
Keywords(s):
Cancer/Oncolo
g
y
,
Lun
g
cancer
,
Repurposed Dru
g
s
,
Small molecule
,
Therapeutics
Category(s):
Life Sciences > Therapeutics
Inhibitors of MNK Kinase for Tar
g
eted Cancer and CNS Therapeutics.
NU 2015-098 (NU 2015-098, NU 2018-036, NU 2025-036) INVENTORS
G
ary Schiltz (Weinberg College of Arts and Sciences, Department of Chemistry)* SHORT DESCRIPTION MNK kinase inhibitors that reduce cancer cell viability and proliferation and penetrates the brain for potential treatment of glioblastoma and CNS disorders. BACKGROUND Leukemia and brain...
Published: 4/29/2026
|
Updated: 4/29/2026
|
Inventor(s):
Keywords(s):
AD - Alzheimer’s Disease
,
AML - Acute myeloid leukemia
,
ASD - Autism Spectrum Disorder
,
Bladder cancer
,
Brain cancer
,
Breast cancer
,
Cancer/Oncolo
g
y
,
CNS - Central Nervous System
,
Colon cancer
,
Lun
g
cancer
,
Neurode
g
enerative disease
,
Pancreatic cancer
,
Prostate cancer
,
Small molecule
,
Tar
g
eted protein degradation
,
Tar
g
eted therapy
,
Therapeutics
Category(s):
Life Sciences > Therapeutics
Use of nucleotide synthesis inhibitors for tar
g
eted therapy in MLL3/4 COMPASS mutant cancer
NU 2022-053 INVENTORS Ali Shilatifard (Feinber
g
School of Medicine, Department of Biochemistry and Molecular Genetics)* Zibo Zhao (Feinberg School of Medicine, Department of Biochemistry and Molecular Genetics)* SHORT DESCRIPTION A therapeutic platform that targets MLL3/4 COMPASS mutant cancers by using nucleotide synthesis inhibitors to disrupt...
Published: 4/29/2026
|
Updated: 4/29/2026
|
Inventor(s):
Keywords(s):
Bladder cancer
,
Breast cancer
,
Cancer/Oncolo
g
y
,
Colon cancer
,
G
astric cancer
,
Leukemia
,
Lun
g
cancer
,
Lymphoma
,
Prostate cancer
,
Tar
g
eted therapy
,
Therapeutics
Category(s):
Life Sciences > Therapeutics
Molecular Ruler for Quantifyin
g
Steady-State and Population Distribution of Photo-Generated Charge Carriers
Provides Quantitative Information on the Steady-State Hot Carriers in Semiconductor and Metal Nanocrystals This DNA-based molecular ruler quantitatively measures the steady-state ener
g
y and population distribution of plasmon-generated hot carriers in metal nanocrystals. Photo-generated charge carriers, such as plasmon-generated hot electrons and holes,...
Published: 4/29/2026
|
Updated: 4/29/2026
|
Inventor(s):
Wei Wei
,
Yue Hu
Keywords(s):
Category(s):
Technolo
g
y Classifications
,
Technolo
g
y Classifications > Engineering > Instrumentation-Sensors-Photonics
Conversational Artificial Intelli
g
ence for Real-Time, Personalized Health Monitoring
A conversational lar
g
e language model (LLM) that analyzes health data and communicates with patients to provide actionable insights. Problem: Wearable devices and implantable sensors generate a deluge of continuous data, but clinicians and patients lack efficient tools to translate this information into timely, actionable insights. Existing monitoring...
Published: 4/29/2026
|
Updated: 4/29/2026
|
Inventor(s):
Brian Litt
,
Zack
G
oldblum
,
Haoer Shi
Keywords(s):
Artificial Intelli
g
ence (AI) & Machine Learning
,
Neurolo
g
y
,
Software
Category(s):
Technolo
g
y Classifications > Digital Health
Tool to Reduce Intrauterine Device Expulsion in Postpartum Women
Placement device for insertin
g
intrauterine devices (IUD) into the postpartum uterus. Problem: An IUD is a small T-shaped device that is placed into the uterus and provides a highly effective method of long-acting reversible contraception. IUDs can be conveniently placed immediately after delivery to prevent unintended pregnancies. A challenge associated...
Published: 4/29/2026
|
Updated: 4/29/2026
|
Inventor(s):
Eileen Wan
g
,
G
abriel Arenas
Keywords(s):
Bioen
g
ineering
,
Women's Health
Category(s):
Technolo
g
y Classifications > Materials
,
Technolo
g
y Classifications > Medical Devices
UWB-Posture
G
uard: A Privacy-Preserving RF Sensing System for Continuous Ergonomic Sitting Posture Monitoring
UWB-Posture
G
uard is an ergonomic posture monitoring technology that continuously detects sitting posture without cameras or wearable devices, while preserving user privacy. The technology is designed for real-time use in everyday desk and seated work environments, providing posture awareness and enabling timely feedback when sustained or potentially...
Published: 4/28/2026
|
Updated: 4/28/2026
|
Inventor(s):
Haotan
g
Li
,
Zhenyu Qi
,
Sen He
,
Kebin Pen
g
,
Shen
g
Tan
,
Yili Ren
,
Tomas Cerny
,
Jiyue Zhao
,
Zi Wan
g
Keywords(s):
Category(s):
Technolo
g
y Classifications > Software & Information Technology > Health IT
,
Technolo
g
y Classifications > Software & Information Technology > Human Machine Interface
,
Technolo
g
y Classifications > Healthcare Portfolios
,
Technolo
g
y Classifications > Imaging & Optics > Sensors and Detection > Remote Sensing
Inte
g
rated Planning for Safer, Smarter Autonomous Urban Driving
This technolo
g
y enables autonomous vehicles to plan high-level tasks and low-level motions in a unified, adaptive framework. By continuously sharing safety and efficiency information between planning layers, vehicles can make smarter decisions in complex, unpredictable urban environments. The result is safer navigation without sacrificing operational...
Published: 4/28/2026
|
Updated: 4/28/2026
|
Inventor(s):
Shiqi Zhan
g
,
Yan Din
g
Keywords(s):
CleanTech
Category(s):
Campus > Bin
g
hamton University
,
Technolo
g
y Classifications > Engineering
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