Search Results - hal+alper

5 Results Sort By:
Engineered sugar uptake in yeast cells
The technology focuses on engineered transporter proteins that enhance the uptake of specific monosaccharides like xylose and arabinose into yeast cells, improving their efficiency and selectivity for biofuel and biochemical production. Background The efficient conversion of lignocellulosic biomass into biofuels and bio­chemicals is a critical...
Published: 8/15/2024   |   Inventor(s): Hal Alper, Eric Young
Keywords(s):  
Category(s): Life sciences > Metabolic engineering, Life sciences > Research tools, Physical sciences > Energy > Renewable
Metabolic engineering of Yarrowia lipolytica for high‑level polyketide production
Background The field of biotechnology has seen significant advancements in the use of genetically modified organisms to produce valuable compounds. Polyketides, a diverse class of secondary metabolites, are of particular interest due to their wide-ranging applications in pharmaceuticals, bioactive compounds, and renewable chemicals. Traditional methods...
Published: 7/11/2024   |   Inventor(s): Hal Alper, Kelly Markham, Claire Palmer
Keywords(s):  
Category(s): Life sciences > Metabolic engineering, Life sciences > Biomaterials, Life sciences > Therapeutics > Synthetic biology
Revolutionizing plastic recycling: FAST-PETase enzyme variant
Background Plastic waste is a pressing ecological challenge, with a staggering 8.3 billion metric tons produced, of which 6 billion tons become waste. Traditional methods of plastic degradation, such as chemical processes, are costly and generate harmful byproducts. Enzymatic degradation presents a sustainable alternative, with poly (ethylene terephthalate)...
Published: 3/4/2024   |   Inventor(s): Hal Alper, Andrew Ellington, Daniel Diaz, Hongyuan Lu
Keywords(s):  
Category(s): Life sciences > Agriculture, Life sciences > Metabolic engineering
Plastic-degrading enzymes
Able to break down PET plastics in as little as 24 hours Overview Plastic waste poses an ecological challenge. There have been 8.3 billion metric tons of plastics produced—6 billion tons are waste. What do we do with this waste? The long-term, sustainable solution is to find effective ways to break down the plastic into smaller parts and then...
Published: 2/28/2024   |   Inventor(s): Hal Alper, Andrew Ellington, Hongyuan Lu
Keywords(s):  
Category(s): Physical sciences > Green tech, Life sciences > Agriculture, Life sciences > Research tools > Reagent
BioPod: A platform for increasing efficiency and reducing costs of biomanufacturing
Problem statement Biology can be harnessed to produce a large share of the global economy’s physical materials, potentially with improved performance and sustainability. Fermentation, for centuries used to brew beer and make bread, is now being used to create high-value ingredients such as collagen and spider silk. According to McKinsey, biologically...
Published: 11/1/2023   |   Inventor(s): Hal Alper, Shuo-Fu Yuan, James Wagner, Trevor Johnston, Alshakim Nelson
Keywords(s): 3D printing, Biologics, Industrial manufacturing, Manufacturing, Pharmaceuticals, Synthesis methods
Category(s): Life sciences > Biomaterials, Life sciences > Therapeutics > Manufacturing platform