Search Results - cloning

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Human CCR2 cDNA
A plasmid encodes human C-C chemokine receptor type 2 (CCR2). CCR2 play important roles in the recruitment of monocytes/macrophages and T cells.
Published: 10/28/2024   |   Inventor(s): Sunil Ahuja, Christophe Combadiere, James Pease, Philip Murphy
Keywords(s): cc, CCR2, cDNA, Cell, Chemokine, Cloning, EOSINOPHIL, Expression, FUNCTIONAL, Human, Including, line., Listed LPM Ano as of 4/15/2015, PLASMID, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, RECEPTOR, RM, WIXXXX
Category(s): Collaboration Sought > Licensing, Application > Research Materials
A Human Progenitor Mast Cell Line for Allergic and Fibrotic Research and Therapeutic Screening
Hermansky-Pudlak Syndrome type-1 (HPS-1) is a rare genetic disorder that affects around 1 in 500,000 people worldwide and 1 in 1,800 Puerto Ricans. Patients with HPS-1 display oculocutaneous albinism, bleeding due to platelet abnormality, and pulmonary fibrosis. Those that develop pulmonary fibrosis often succumb and live no more than a decade after...
Published: 10/28/2024   |   Inventor(s): Dean Metcalfe, Arnold Kirshenbaum
Keywords(s): 16bp, c.1470-1486dup16, Cell, Cells, Cloning, Defect, DUPLICATION, EXPANSION, Expressing, FceRI, Hermansky, HPM, HPS1, Human, Immature, KNOWN, Line, Promastocyte, Pudlak, RECEPTORS, Syndrome-1
Category(s): Collaboration Sought > Collaboration
Myosin-Based Protein-Protein Interaction Assay
Investigators at the National Institute on Deafness and Other Communication Disorders (NIDCD) have developed an assay for the detection of protein-protein interactions in living cells. This assay uses readily-available reagents and straightforward techniques that avoid the difficulty of purifying proteins or generating antibodies required for other...
Published: 10/28/2024   |   Inventor(s): Thomas Friedman, Inna Belyantseva, Erich Boger
Keywords(s): [DC-023], [DC-024], [DC-025], [DC-026], [DC-027], [DC-028], [DC-029], 10, AC4XXX, AC5XXX, ACXXXX, assay, AXXXXX, cDNA, cDNAS, chimeric, Cloning, DsRed-tagged, ELEVEN, Flourescent, fluorescent, Fluorescent probe, Fourteen, Fusion, GFP, GFP-Myo, GFP-Myo10, GFP-MyolO, GFP-myosin, GFp-whirlin, GREEN, HEAVY, HMM, INTERACTION, KINESIN, Meromyosin, Mouse, MYOSIN, ONE, Patent Category - Biotechnology, Plasmic, PLASMID, Protein, PROTEIN-PROTEIN, PROTEIN-PROTEIN interactions, SIX, Sixteen, TAGGED, Twenty, Twenty-two, whirlin, X, XVa
Category(s): Collaboration Sought > Licensing, Collaboration Sought > Materials Available
Molecular Cloning and Characterization of SNAPIN: A Synaptic Vesicle Protein Implicated in Neurotransmitter
Neurotransmitter release is dependent on a binding complex (designated as SNAR) of three proteins, synaptic-vesicle-associated protein synaptobrevin/VAMP, syntaxin and SNAP-25 (snaptosome-associated protein-25) with results in a calcium dependent fusion between synaptic vesicles and the presynaptic terminal. SNAPIN, a neuron specific protein found...
Published: 4/8/2024   |   Inventor(s): Jeffrey Ilardi, Zu-hang Sheng
Keywords(s): ac5AXX, AC5XXX, ACXXXX, AXXXXX, CHARACTERIZATION, Cloning, implicated, Listed LPM Maddox as of 4/15/2015, Molecular, NEUROTRANSMITTER, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, Protein, Snapin:, SYNAPTIC, VESICLE
Category(s): Collaboration Sought > Licensing
Isolation, Cloning and Characterization of New Adeno-Associated Virus (AAV) Serotypes
Adeno-associated viruses (AAV) are used in gene delivery, but with limited success due to toxicity. The novel AAVs described in this technology may be more effective and useful in gene therapy applications. This invention relates to new adeno-associated viruses (AAV), vectors and particles derived therefrom and also provides methods for delivering...
Published: 10/28/2024   |   Inventor(s): John (Jay) Chiorini, Michael Schmidt
Keywords(s): Adeno-associated, CHARACTERIZATION, Cloning, GB2A2X, GB2AXX, GB2XXX, GBXXXX, GXXXXX, Isolation, Novel, Serotypes, virus
Category(s): Application > Therapeutics