Search Results - chemokine

4 Results Sort By:
Transformation of Weak or Non-Immunogenic Antigens to Produce an Immune Response and Therapeutic Polypeptides for the Treatment and Prevention of Cancer
Abstract: A significant challenge in developing therapies for the treatment and prevention of cancer has been the discovery, selection, and exploitation of antigens. Researchers at the National Institute on Aging (NIA) have partially circumvented this issue in their development of novel strategies for rendering weakly or non-immunogenic, shared antigens...
Published: 4/8/2024   |   Inventor(s): Bira Arya, Dan Longo, Igor Espinoza-Delgado
Keywords(s): ANTIGEN, Biragyn, CANCER VACCINE, Chemokine, National Institute on Aging, NIA
Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Oncology, Collaboration Sought > Licensing, Application > Therapeutics
Human CC Chemokine Receptor CX3CR1 / CMKBRL1 cDNA
A plasmid encodes human CC chemokine receptor CX3CR1/CMKBRL1 as described in DNA Cell Biol. 1995 Aug;14(8):673-80, and developed in the laboratory of Philip M. Murphy at the National Institute of Allergy and Infectious Diseases.
Published: 10/28/2024   |   Inventor(s): Philip Murphy
Keywords(s): cc, CC-CMKBRL1, cDNA, Chemokine, Human, PLASMID, RECEPTOR, RM, WIXXXX
Category(s): Collaboration Sought > Licensing, Application > Research Materials
Human CCR2 cDNA
A plasmid encodes human C-C chemokine receptor type 2 (CCR2). CCR2 play important roles in the recruitment of monocytes/macrophages and T cells.
Published: 10/28/2024   |   Inventor(s): Sunil Ahuja, Christophe Combadiere, James Pease, Philip Murphy
Keywords(s): cc, CCR2, cDNA, Cell, Chemokine, Cloning, EOSINOPHIL, Expression, FUNCTIONAL, Human, Including, line., Listed LPM Ano as of 4/15/2015, PLASMID, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, RECEPTOR, RM, WIXXXX
Category(s): Collaboration Sought > Licensing, Application > Research Materials
CC Chemokine Receptor 5 DNA, New Animal Models and Therapeutic Agents for HIV Infection
Chemokine receptors are expressed by many cells, including lymphoid cells, and function to mediate cell trafficking and localization. CC chemokine receptor 5 (CCR5) is a seven-transmembrane, G protein-coupled receptor (GPCR) which regulates trafficking and effector functions of memory/effector T-lymphocytes, macrophages, and immature dendritic cells....
Published: 10/28/2024   |   Inventor(s): Christopher Broder, Philip Murphy, Ghalib Alkhatib, Edward Berger, Yu Feng, Paul Kennedy, Christophe Combadiere
Keywords(s): 5, Agents, AIDS, also designated as CKR5, ANIMAL, antiretroviral, ANTIVIRAL, cc, CC-CKR5 chemokine receptor, CCR5 and CMKBR5, Chemokine, DB4AXX, DB4XXX, DBXXXX, DDXXXX, DNA, DXXXXX, HIV, Hyper IgM syndrome, Immunodeficiency 2, Immunodeficiency 4, Immunodeficiency-3, Infection, MIP-1a & MIP-1b, Models, Patent Category - Biotechnology, Patent Category - Contested Proceedings, RECEPTOR, receptor for RANTES, Severe combined immunodeficiency, x-linked, therapeutic, Wiskott Aldrich syndrome
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Research Materials, TherapeuticArea > Infectious Disease, Application > Therapeutics