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RPI ID: 2022-059-201 Innovation Summary: This cranial fixation technology introduces a specialized bone fixation system designed for use after craniectomy procedures. The device enhances mechanical stability and promotes better healing outcomes by securely anchoring cranial bone segments. It incorporates features that accommodate anatomical variability...

Published: 3/10/2026 | Inventor(s): Max Phoenix, John Lurie, Akanksha Singh, Mousa Hamad, Luke Kaiser

Keywords(s): BME Capstone, Craniectomy, Cranioplasty, expansion, ICP, intercranial pressure, reconstruction, support, surgical optimization, titanium

Category(s): Biotechnology and the Life Sciences

A Human Progenitor Mast Cell Line for Allergic and Fibrotic Research and Therapeutic Screening

Hermansky-Pudlak Syndrome type-1 (HPS-1) is a rare genetic disorder that affects around 1 in 500,000 people worldwide and 1 in 1,800 Puerto Ricans. Patients with HPS-1 display oculocutaneous albinism, bleeding due to platelet abnormality, and pulmonary fibrosis. Those that develop pulmonary fibrosis often succumb and live no more than a decade after...

Published: 8/13/2025 | Inventor(s): Dean Metcalfe, Arnold Kirshenbaum

Keywords(s): 16bp, c.1470-1486dup16, Cell, Cells, Cloning, Defect, DUPLICATION, EXPANSION, Expressing, FceRI, Hermansky, HPM, HPS1, Human, Immature, KNOWN, Line, Promastocyte, Pudlak, RECEPTORS, Syndrome-1

Category(s): Collaboration Sought > Collaboration

Cell Based Immunotherapy

The invention hereby offered for licensing is in the field of Immunotherapy and more specifically in therapy of autoimmune diseases such as Type I diabetes, multiple sclerosis, rheumatoid arthritis and systemic lupus erythematosis and immune mediated allergies such as asthma as well as in transplantation-related disorders, such as graft acceptance...

Published: 10/28/2024 | Inventor(s): Ethan Shevach, Dat Tran

Keywords(s): 2, ACTIVATED, ALLOWS, Aplastic anemia, Aplastic anemia, idiopathic; Aplastic anemia, Associated, CD121b, CELL-BASED, Cells, CULTURES, EXPANSION, Expression, FOXP3+, Generate, Graft versus host disease, Human, IB3XXX, IBXXXX, Idiopathic thrombocytopenic purpura, IL-l, Immunotherapy, IXXXXX, LAP, Latency, NUMBERS, Patent Category - Biotechnology, Peptide, purification, RECEPTOR, Regulatory, SELECTIVE, Sufficient, Systemic lupus erythematosus, T, Their, Thrombocytopenic purpura, autoimmune, TYPE

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Therapeutics, TherapeuticArea > Immunology, Application > Diagnostics, Application > Research Materials