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Luminescent biosensor for detection of nucleotide sequences, small molecules, and proteins at the point-of-care
This technology is a modular, luminescent biosensor that rapidly detects DNA, RNA, small molecules, and proteins at the point of care, using a visible color change measurable by a smartphone, enabling fast, sensitive, and equipment-free diagnostics. Background: Molecular diagnostics is a rapidly evolving field that plays a critical role in the detection...
Published: 7/27/2026   |   Updated: 7/27/2026   |   Inventor(s): Harsimranjit Sekhon, Stewart Loh
Keywords(s): bio/chemical sensors, bioluminescence, biomarker diagnostics, biosensor, nanoluciferase, Technologies, therapeutic drug monitoring, Virus Detection
Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Diagnostics
Ostomy leak detection system
The Ostomy Leak Detection System is an innovative technology designed to provide early and reliable detection of ostomy pouch leaks through an electrochemical sensor, enhancing patient comfort and health outcomes. Background: Ostomy pouch leakage is a common and challenging issue faced by individuals with ostomies. Leaks can cause extended skin exposure...
Published: 7/23/2026   |   Updated: 7/23/2026   |   Inventor(s): Fnu Alvina
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Healthcare
Single Use Minimally Invasive Orthopedic Bone Biopsy and Graft Introduction Tray
The Single Use Minimally Invasive Orthopedic Bone Biopsy and Graft Introduction Tool Tray is an all-inclusive, innovative tool tray designed to improve the efficiency and effectiveness of orthopedic macro biopsies through a safe, secure, controlled minimally invasive approach even through normal intact cortical bone. Background: Orthopedic surgeons...
Published: 6/29/2026   |   Updated: 6/25/2026   |   Inventor(s): Timothy Damron
Keywords(s): biopsy, bone, bone filler, bone graft, minimally invasive, orthopedic oncology, orthopedic surgery, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering
Customizable implantable testicular prosthetics
This innovation introduces a customizable implantable testicular prosthesis with an adjustable size, enabling precise fit and improved surgical outcomes. Background: Existing testicular prosthetics are typically available as either pre-sized balloon-type implants or solid silicone models. These fixed-size options often present challenges during surgery,...
Published: 6/29/2026   |   Updated: 6/24/2026   |   Inventor(s): Dmitriy Nikolavsky, Gennady Bratslavsky
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Assistive Technology
Kcnh2 Mutant Rabbit
Genetic animal model of Long QT Syndrome Type-2 (LQT2) reproduces the neuro-cardiac pathologies and high risk of sudden death seen in people with LQT2, and provides a platform for advanced research and drug testing. Background: Long QT Syndrome Type-2 (LQT2) is due to genetic variants in the Kcnh2 gene, which encodes a potassium channel protein that...
Published: 6/29/2026   |   Updated: 6/24/2026   |   Inventor(s): David Auerbach
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Research Tools and Reagents
Procedure for Pre-Clinical Continuous EEG/ECG Monitoring
This technology introduces a novel surgical procedure, custom implant, and wiring harness for continuous electroencephalogram (EEG) and electrocardiogram (ECG) monitoring in conscious unrestrained animals. The animal is chronically implanted with subdermal electrodes and connected to a durable wiring system to capture high-quality physiological data....
Published: 6/29/2026   |   Updated: 6/24/2026   |   Inventor(s): David Auerbach, Kyle Wagner, Laura Williams
Keywords(s): animal models, animal studies, bioengineering, biomedical science, biosensor, electrocardiogram, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Diagnostics
Development of an Out-of-Hospital ECG-Based Diagnostic Biomarker to Distinguish Epileptic vs. Functional/Dissociative Seizures
This innovation presents a machine learning-based diagnostic tool that uses an electrocardiogram (ECG) signal to accurately distinguish between convulsive epileptic seizures and functional/dissociative seizures. Background: Diagnosing epileptic seizures (ES) versus functional/dissociative seizures (FDS) is complex and traditionally depends on long-term...
Published: 6/29/2026   |   Updated: 6/24/2026   |   Inventor(s): David Auerbach, Justin Ryan, Kyle Wagner
Keywords(s): biomarkers, epilepsy, seizures, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Diagnostics
A novel SHIP1-selective inhibitor to induce blood cell recovery and stem cell engraftment
A32 is a highly selective small molecule that inhibits the SHIP1 enzyme, boosting blood cell growth factors and potentially improving recovery and immunity after chemotherapy, radiation, or stem cell transplantation, without affecting the related SHIP2 enzyme. Background: Hematopoiesis, the process by which blood cells are formed, is critical for...
Published: 6/29/2026   |   Updated: 6/24/2026   |   Inventor(s): William Kerr, Chiara Pedicone, Denzil Bernard
Keywords(s): bleeding disorders, Blood cell recovery, fungal infection, neutrophils, platelets, stem cell transplants, Technologies
Category(s): Technology Classifications > Therapeutics and Vaccines, Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering
Bi-Directional mTOR Blockade and Companion Biomarkers of Flare and Predictors of Therapeutic Efficacy in SLE
Novel therapeutic intervention targeting mTOR pathways combined with companion biomarkers enables personalized treatment of SLE and its liver complications. Background: Systemic lupus erythematosus (SLE) is a chronic, heterogeneous autoimmune disorder marked by dysregulated immune activity, systemic inflammation, and progressive damage across multiple...
Published: 6/29/2026   |   Updated: 6/23/2026   |   Inventor(s): Andras Perl
Keywords(s): biomarker diagnostics, biomarkers, drug efficacy, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering
Utilize lipid nanoparticle-based CRISPR/Cas9 genome editing to delete the Pfkp gene for the treatment of head and neck cancer
This technology introduces a novel lipid nanoparticle-based CRISPR/Cas9 system designed to target the Pfkp gene for the effective treatment of head and neck cancer. Background: Head and neck cancer continues to pose a significant clinical challenge due to its aggressive nature and poor patient prognosis. A primary contributing factor is the overexpression...
Published: 6/22/2026   |   Updated: 6/21/2026   |   Inventor(s): Yamin Li
Keywords(s): cancer, cancer therapy, lipids, nanoparticle, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Gene Therapy, Technology Classifications > Therapeutics and Vaccines
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