Search Results - campus+%3e+upstate+medical+university

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Diabetic Foot Examiner
This technology enables diabetic patients to detect foot ulcers easily and effectively at home. Background: Diabetic foot ulcers are a significant health problem (15% baseline probability) in the growing diabetic population. Foot ulcers can become infected and lead to hospitalization or even amputation. The best way to address this disease is through...
Published: 3/13/2026   |   Inventor(s): Ronald Miller
Keywords(s): artificial intelligence, diabetes, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Healthcare
3D-Printed Theranostic Dose Caddy
This technology enables safer administration of radioligand therapies, allowing for healthier, lower radiation doses to both patients and administering staff. Background: At present, there are two FDA-approved radioligand therapies for broad use in cancer treatment: Lutathera (177Lutetium DOTATATE) and Pluvicto (177Lutetium Vipivotide Tetraxetan)....
Published: 3/13/2026   |   Inventor(s): David Lubin, David Feiglin, Kurtis Wilson, Leen Alkukhun, Garrett Depalma, Kent Ogden, Mary McGrath, Paul Depew, Zohaib Khan, Meghan Stanton
Keywords(s): 3D printing, cancer therapy, radiology, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Healthcare
Netrin-4–Mediated Disruption of Basement Membranes for Targeted Therapeutic Delivery
Novel tools that promote the delivery of therapeutics to treat inner retinal diseases such as diabetic retinopathy, retinal vein occlusion, and retinitis pigmentosa. Background: Non-surgical access to tissues for direct biological manipulation, e.g. gene transfer, stem cell transplantation, and drug delivery, can be difficult because many tissues...
Published: 3/9/2026   |   Inventor(s): Dale Hunter, William Brunken, Peter Yurchenco, Karen Mckee
Keywords(s): biologic therapies, drug delivery component, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Drug Delivery, Technology Classifications > Therapeutics and Vaccines
Modular Hybrid Simulator (Endovascular Flow model with embedded sensors for operative feedback) powered by 3D auto segmentation software for Endovascular Modeling and Flow Model additions.
The Modular Hybrid Simulator is an advanced training platform for endovascular procedures, combining patient-specific 3D modeling with real-time operative feedback to enhance learning and procedural planning. Background: Endovascular training currently faces challenges such as inconsistent learning curves among trainees and the limitations of existing...
Published: 3/3/2026   |   Inventor(s): Hesham Masoud
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Healthcare
Ultrasonic Transmission System with Modular Cavitation-Enhancing Wire
This device uses ultrasonic vibrations delivered through a specialized wire to safely and efficiently clear blockages or remove implants from medical tubes, offering a non-invasive, customizable solution for maintaining and treating tube obstructions in healthcare settings. Background: Nephrostomy tubes and other indwelling medical devices are critical...
Published: 3/3/2026   |   Inventor(s): Alexander Collins, Scott Wiener
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Healthcare
Targeting RNA Polymerase I Protein–Protein Interfaces Using Peptide Inhibitors: A Computational Strategy Powered by PepTelligence, a Comprehensive Peptide Scoring System
PepTelligence is an innovative computational tool designed to evaluate and optimize therapeutic peptides by integrating multiple biochemical and pharmacological factors into a unified scoring system. Background: The development of PepTelligence addresses a significant challenge in peptide drug discovery: the absence of a comprehensive evaluation...
Published: 2/25/2026   |   Inventor(s): Maryam Kabiri, Bruce Knutson
Keywords(s): multi-parameter scoring, peptide design, peptide drug discovery, peptide scoring system, structural bioinformatics, Technologies, therapeutic peptides
Category(s): Technology Classifications > Computer Software, Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering
A novel synthetic constitutive-active glucocorticoid receptor
Introducing "superGR," a novel synthetic glucocorticoid receptor fusion protein designed to enhance glucocorticoid therapy by providing ligand-independent activation and improved gene regulation for inflammatory diseases. Background: Glucocorticoids are widely used to treat inflammatory conditions like severe alcoholic hepatitis and sepsis,...
Published: 3/9/2026   |   Inventor(s): Hong Lu, Conor Fahy
Keywords(s): gene therapy, glucocorticoid, inflammatory liver disease, lung injury, sepsis, synthetic materials, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering
Luminescent biosensor for detection of nucleotide sequences, small molecules, and proteins at the point-of-care
This technology is a modular, luminescent biosensor that rapidly detects DNA, RNA, small molecules, and proteins at the point of care, using a visible color change measurable by a smartphone, enabling fast, sensitive, and equipment-free diagnostics. Background: Molecular diagnostics is a rapidly evolving field that plays a critical role in the detection...
Published: 3/9/2026   |   Inventor(s): Harsimranjit Sekhon, Stewart Loh
Keywords(s): bio/chemical sensors, bioluminescence, biomarker diagnostics, biosensor, nanoluciferase, Technologies, therapeutic drug monitoring, Virus Detection
Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Diagnostics
Dual Inhibition of RNA Polymerase I and III as a Novel Strategy for Targeting Ribosome Biogenesis in Cancer
A specially designed peptide blocks two key enzymes needed for ribosome production in cancer cells, shutting down their protein-making machinery and offering a new, more effective way to treat cancer and prevent drug resistance. Background: Ribosome biogenesis is a fundamental cellular process involving the coordinated synthesis of ribosomal RNA...
Published: 3/13/2026   |   Inventor(s): Haleigh Pascual, Bruce Knutson
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Therapeutics and Vaccines
Generation of a single-chain recombinant IgA1 isotype antibody compatible with in vivo nucleic acid delivery for the treatment and prevention of flavivirus infection
This technology uses a single-chain IgA1 antibody delivered by DNA or RNA to enable the body to produce its own protection against dengue and Zika viruses, offering rapid, safe, and scalable prevention and treatment without risk of antibody-dependent enhancement. Background: Flavivirus infections, including those caused by dengue and Zika viruses,...
Published: 2/17/2026   |   Inventor(s): Adam Waickman, Stephen Thomas
Keywords(s): antibody therapy, infectious diseases, nucleic acid, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Antibodies, Technology Classifications > Healthcare
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