Search Results - yaning+li

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Summary The National Cancer Institute (NCI) seeks research co-development partners and/or licensees for a class of novel aplithianine-derived small molecule analogs that compete with ATP for binding on a range of clinically relevant kinases including: Oncogenic gene fusion DNAJB1-PRKACA (PKADJ) Wild type protein kinase A (PKA) Protein kinase...

Published: 12/20/2024 | Inventor(s): Barry O'Keefe, Lin Du, Brice Wilson, Ping Zhang, William Moore, Dongdong Wang, Juliana Martinez Fiesco, Ning Li

Keywords(s):

Category(s): Application, Application > Therapeutics, Collaboration Sought > Collaboration, TherapeuticArea > Oncology, TherapeuticArea > Rare / Neglected Diseases, TherapeuticArea > Infectious Disease, Collaboration Sought > Licensing

Reverse Thiazine Kinase Inhibitors

Published: 12/19/2024 | Inventor(s): Barry O'Keefe, Lin Du, Brice Wilson, Ping Zhang, William Moore, Dongdong Wang, Juliana Martinez Fiesco, Ning Li

Keywords(s):

Category(s): Application > Therapeutics, Collaboration Sought > Collaboration, TherapeuticArea > Oncology, TherapeuticArea > Infectious Disease, TherapeuticArea > Rare / Neglected Diseases, Collaboration Sought > Licensing

Novel Kinase Inhibitory Aplithianines

Published: 12/20/2024 | Inventor(s): Barry O'Keefe, Lin Du, Brice Wilson, Ping Zhang, William Moore, Dongdong Wang, Juliana Martinez Fiesco, Ning Li

Keywords(s):

Category(s): Application > Therapeutics, TherapeuticArea > Oncology, TherapeuticArea > Infectious Disease, TherapeuticArea > Rare / Neglected Diseases, Collaboration Sought > Collaboration, Collaboration Sought > Licensing

Bi-modulus Adaptive Mechanical Metamaterials (AMM) towards Infinity-D Printing

INV-23086 Background: Mechanical metamaterials are designed to have unique properties like flexibility and toughness, making them essential in industries such as aerospace, automotive, and civil engineering. These materials need to withstand extreme conditions and improve the safety and durability of structures. However, current materials often fail...

Published: 9/10/2024 | Inventor(s): Yaning Li

Keywords(s): Mechanical Metamaterials

Category(s): Technology Classifications > 2. Physical Science

New Fiber-Matrix Composites with Negative Poisson's Ratio

INV-23063 Background Materials with a negative Poisson's ratio, known as auxetics, have been studied for use in applications that can resist in-plane or out-of-plane loads. When stretched these materials uniquely expand perpendicular to the applied force. However, their widespread adoption faces significant hurdles due to their typical foam-like,...

Published: 10/15/2024 | Inventor(s): Yaning Li

Keywords(s):

Category(s): Technology Classifications > 1. Life Science

An OCT method to improve scleral lens fitting

Summary The current technology allows for accurate and objective 3-dimensional (3D) mapping of the external limbus, which could ultimately improve the process of scleral lens fitting. Technology Overview Rigid scleral lenses are difficult to fit to patients because they must rest on the eye but vault over the cornea and the limbus, which is the transition...

Published: 1/5/2024 | Inventor(s): David Huang, Yan Li, Clara Llorens Quintana

Keywords(s): Imaging, Imaging - Other, Software, Software - Diagnostic/Detection

Category(s): Imaging, Software

PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids

The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...

Published: 7/30/2024 | Inventor(s): Payman Dehghanian, Shiyuan Wang, Li Li

Keywords(s):

Category(s): Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment

New smart mechanical metamaterials with tunable stimuli-responsive expansion coefficients

INV-21073 Background Smart Materials are materials with one or more properties that can be significantly changed in a controlled fashion by externally applied stimuli such as stress, temperature, and electric/magnetic fields. The response can be reversible and demonstrated by changes in physical properties such as shape, stiffness, and viscosity...

Published: 9/10/2024 | Inventor(s): Yaning Li

Keywords(s): 3D printing, 4D Printing, Expansion coefficient, Mechanical Metamaterials

Category(s): Technology Classifications > 2. Physical Science > Advanced materials/Nanomaterials

Three Dimensional Auxetic Tiled Composites

New auxetic materials with higher stiffness, strength, and adaptability through large mechanical load and shear https://nu.technologypublisher.com/files/sites/adobestock_988355353.jpeg https://nu.technologypublisher.com/files/sites/mark-saulich-1280x1600.jpg Source: Author Irina/ Adobe Stock # 988355353 INV-21121 Background Auxetic materials...

Published: 10/16/2024 | Inventor(s): Yaning Li

Keywords(s): Mechanical Metamaterials

Category(s): -Biomedical Materials, Technology Classifications > 2. Physical Science > Advanced materials/Nanomaterials

Control Plane System to Safely and Accurately Transfer Large Amounts of Data

Establishes Dedicated Bandwidths and Reserves Specific Channels to Efficiently Convey InformationThis device is designed to control access to a network which can be utilized by a variety of industries to safely and accurately transfer large amounts of data. High Bandwidth Systems are increasingly using control plane for managing the traffic on the network....

Published: 4/21/2023 | Inventor(s): Sartaj Sahni, Sanjay Ranka, Yan Li, Eun-Sung Jung, Nara Kamath, Nageshwara Rao

Keywords(s): Backend Signaling, Bandwidth Scheduling, broadband technologies, data processing/data interchange, middleware, data protection, storage technology, cryptogr, Dedicated Bandwidth Channels, Future Resource Scheduling, GMPLS, In-Advance Circuit Provisioning, internet technologies/communication (wireless

Category(s): Technology Classifications > Engineering > Computer Science

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