Search Results - women%e2%80%99s+health

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New Potential Therapeutic Method for Leiomyoma: Co-Inhibition of FKBP51 and HSD11B1
Advantages: Novel approach for leiomyoma treatment: Direct disruption of the FKBP51-GR-HSD11B1 signaling loop Stronger GR suppression than single-target hormone therapies Targeted leiomyoma treatment: Modulates GR activity, control cortisol production and ECM generation Minimizes hormonal side effects, offering a fertility-friendly alternative...
Published: 3/12/2025   |   Inventor(s): Charles Lockwood, Ozlem Guzeloglu-Kayisli, Carrie Malcom, Umit Kayisli
Keywords(s): Women’s Health
Category(s): Technology Classifications > Medical > Womens Health
Early Screening Method for Fetal Growth Restriction (FGR)
Advantages: Earlier diagnosis than traditional FGR screening: can detect risk as early as the 1st or 2nd trimester Non-invasive testing with maternal blood Superior sensitivity and specificity compared to ultrasound-based detection Can be potentially further developed into a commercial product/ standard prenatal screening test for DNA methylation...
Published: 3/4/2025   |   Inventor(s): Umit Kayisli, Anthony Odibo, Charles Lockwood, Ozlem Guzeloglu-Kayisli
Keywords(s): Women’s Health
Category(s): Technology Classifications > Medical > Medical Diagnostics, Technology Classifications > Medical > Womens Health
Prevention of Abnormal Uterine Bleeding Caused by Progestin-Only Long-Acting Reversible Contraceptives
Advantages: 15dPGJ2 blocks the proliferation of human endometrial endothelial cells, thereby preventing pLARC-induced aberrant endometrial angiogenesis, a major cause of unexpected uterine bleeding 15dPGJ2 enhances progestin responsiveness and prevents pLARC-induced inflammation, another contributor to uterine vascular instability, effectively reducing...
Published: 2/19/2025   |   Inventor(s): Charles Lockwood, Ozlem Guzeloglu-Kayisli, Umit Kayisli
Keywords(s): Women’s Health
Category(s): Technology Classifications > Medical, Technology Classifications > Chemistry, Technology Classifications > Medical > Pharmaceuticals
Comprehensive and Individualized Menopause Care Delivery Protocol With Technological Decision Support Aid (Case No. 2024-193)
Summary: Researchers in the UCLA Department of Obstetrics and Gynecology have developed a new clinical decision support system for improved menopause care. Background: Each year, approximately 1.3 million women in the United States enter menopause. This is often accompanied by symptoms such as hot flashes, mood changes, and sleep issues. In addition,...
Published: 2/14/2025   |   Inventor(s): Rajita Patil, Erica Oberman, Brittany Davis, Rhonda Voskuhl, Kathleen Van Dyk, Ravi Aysola, Louise Dixon De Silva, Karol Watson, Lua Jafari, Julie Bernthal, Rashmi Mullur, Albert Shieh, Elizabeth Ko, Katie Hu, Aashini Master, Kelly Mccann, Kelsey Collins, Katherine Unverferth, Tamara Grisales, Amy Rosenman, Andrea Rapkin
Keywords(s): clinical care methodology, clinical decision support, EHR, EHR integration, electronic health records (EHR), FemTech, femtech medical device, lab results analysis, medical bias reduction, Menopause, menopause management, patient questionnaire, period, personalized medicine, predictive analytics, specialist referral, women’s health
Category(s): Software & Algorithms, Software & Algorithms > Programs, Software & Algorithms > Digital Health, Software & Algorithms > Artificial Intelligence & Machine Learning, Medical Devices, Medical Devices > FemTech
Short Nuclear Repeat Element (SINE) RNA of Imprinted MicroRNA Clusters Mediate the Intrinsic, Type III Interferon-driven Viral Resistance of Hemochorial Placentas
­Advantages: Enhanced understanding of improved prenatal protection: Discovered a novel mechanism by which SINE RNA mediate intrinsic antiviral resistance in the placenta Opens the door to therapeutic intervention Summary: Addressing a fundamental challenge in prenatal health, this research investigates how the placenta at the maternal-fetal...
Published: 9/26/2023   |   Inventor(s): Hana Totary-Jain
Keywords(s): Medical Therapeutics Gene Therapy, Women’s Health
Category(s): Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Medical > Womens Health
Novel target to treat the growth of uterine leiomyomas
Advantages: Our investigators have identified restricted patterns of CD73 expression that broadly implicate extracellular adenosine as a key mediator for the growth of uterine leiomyomas. Targeting activity at Type2B adenosine receptors could be potentially used as a strategy to shrink leiomyomas while avoiding potential limitation and systemic...
Published: 9/3/2024   |   Inventor(s): Matthew Anderson, Xiaofang Guo, Umit Kayisli
Keywords(s): Cancer Diagnostics, Cancer Treatment, Women’s Health
Category(s): Technology Classifications > Cancer > Cancer Diagnostics
Preventing Alu SINEs-Mediated Immune Pathologies
Advantages: Discovered a novel mechanism of anti-viral defense during pregnancy Developed a novel method to predict susceptibility for viral infections during pregnancy Developed a novel method to treat interferon-related pathologies with maladaptive immune responses Business Summary: Viral infections during pregnancy cause devastating effects...
Published: 8/21/2024   |   Inventor(s): Hana Totary-Jain
Keywords(s): Antiviral Therapeutics, Therapeutics, Women’s Health
Category(s): Technology Classifications > Medical, Technology Classifications > Medical > Medical Diagnostics, Technology Classifications > Medical > Womens Health, Technology Classifications > Medical > Therapeutics, Technology Classifications > Medical > Infectious Diseases, Technology Classifications > Medical > Biotechnology
Cistron Mediated Intrinsic Interferon and Antiviral Response in Human Placenta
Competitive Advantages Predict susceptibility for infection or severity of infection in pregnant women Reduced viral infections during pregnancy Protection of both maternal and fetal health against infections Uses the placenta at the maternal-fetal interfaces for antiviral response Summary Viral infections during pregnancy have often caused...
Published: 2/6/2025   |   Inventor(s): Hana Totary-Jain
Keywords(s): Infectious Diseases Treatment, Women’s Health
Category(s): Technology Classifications > Medical > Infectious Diseases, Technology Classifications > Medical > Womens Health