Search Results - will+wright

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Small molecules hits, and companion diagnostic, selective for the ATP generating activity of NUDT5. We are developing lead compounds that eventually could be used to complement poly ADP-ribose polymerase therapy or as a treatment on itself as an alternative treatment option to treat primary and metastatic cancers. Technology: Recurrence and metastasis...

Published: 10/4/2024 | Inventor(s): Miguel Beato, Roni Wright

Keywords(s): Metastasis, Oncology

Category(s): Drug Targets & Mechanisms, Therapeutics (Biologics & Compounds)

Methods of Treating Diffuse Large B Cell Lymphoma Based on Particular Genetic Subtype (LymphGen) - A Genetic Classifier to Aid in the Molecular Diagnosis and Treatment of Diffuse Large B-cell Lymphoma

Abstract: The development of precision medicine approaches for DLBCL (Diffuse Large B Cell Lymphoma) is complicated by its genetic, phenotypic and clinical heterogeneity. Current classification methods do not fully explain the observed differences in clinical outcomes to current chemotherapy and targeted therapy. Therefore, better analytical methods...

Published: 8/14/2024 | Inventor(s): George Wright, Louis Staudt, Calvin Johnson, Da Wei Huang

Keywords(s): Diffuse Large B Cell Lymphoma, DLBCL, LymphGen, Precision Medicine, PREDICTIVE, Staudt

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Diagnostics

Molecular Classification of Primary Mediastinal Large B Cell Lymphoma Using Formalin-Fixed, Paraffin-Embedded Tissue Specimens

Abstract: Primary mediastinal B-cell lymphoma (PMBCL) is an aggressive type of non-Hodgkin lymphoma that mostly occurs in people between the ages of 30-40. It accounts for 5-7% of all aggressive lymphomas. The diagnosis of PMBCL is challenging as the histological features of PMBCL overlap with diffuse large B-cell lymphoma (DLBCL), another most common...

Published: 4/8/2024 | Inventor(s): Louis Staudt, Lisa Rimsza, David Scott, George Wright, Anja Mottok, Christian Steid, Elaine Jaffe, Randy Gascoyne, Elias Guerri, Elias Guerri, Elias Guerri, Andreas Rosenwald, Kai Fu, Timothy Greiner, Erlend Smeland, Jan Delabie, Rita Braziel, Wing Chan, Joo Song, Dennis Weisenburger, German Ott, James Cook

Keywords(s): assay, Diffuse Large B Cell Lymphoma, DLBCL, FFPE, Formalin-fixed, GENE EXPRESSION, paraffin-embedded biopsies, PMBCL, Primary Mediastinal Large B Cell Lymphoma, Staudt

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Diagnostics

Clinical Outcome Predictors for Mantle Cell Lymphoma

Abstract: Mantle cell lymphoma (MCL) is a group of aggressive B-cell lymphomas displaying heterogeneous outcomes after treatment. Some patients have the slowly progressing disease that does not require immediate treatment, while others have a disease that rapidly progresses despite highly aggressive treatment. A number of prognostic tools have been...

Published: 8/14/2024 | Inventor(s): Louis Staudt, David Scott, George Wright, Andreas Rosenwald, Pau Abrisqueta, Rita Braziel, Elias Guerri, Wing Chan, Joseph Connors, Diego Villa, Kai Fu, Randy Gascoyne, Timothy Greiner, Elaine Jaffe, Graham Slack, James Cook, Jan Delabie, German Ott, Lisa Rimsza, Dennis Weisenburger, Anja Mottok, Pedro Jares

Keywords(s): B-cell lymphomas, Gene expression profile, Mantle cell lymphoma, Prognostic tool

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Diagnostics, TherapeuticArea > Oncology

Carbonate-Infused Activated Carbon for Direct Air Capture Sorbents

Background Removal of carbon dioxide (CO2) from the atmosphere by direct air capture (DAC) can be accomplished using two chief approaches, liquid and solid. Liquid systems pass air through chemical solutions containing basic ions (e.g., hydroxide ions or bicarbonate ions), heat the resulting mixture to release the captured CO2, and then reuse the...

Published: 2/13/2025 | Inventor(s): Matthew Green, Meng Wang, Jae Sang Lee, Klaus Lackner, Mani Modayil Korah, Husain Mithaiwala, Allen Wright

Keywords(s): Environmental, Fuel Cells, Energy

Category(s): Physical Science, Environmental Remediation/Wastewater Treatment, Environmental, Manufacturing/Construction/Mechanical

Electrospun K₂CO₃/Activated-Carbon Composites for Carbon Dioxide Capture

Background Direct air capture (DAC) is a process of capturing carbon dioxide (CO2) directly from air. The CO2 can be captured when the air contacts a chemical medium or functionalized sorbent, and then removed from the chemical medium or functionalized sorbent to yield a CO2 stream. Invention Description Researchers at Arizona State University...

Published: 2/13/2025 | Inventor(s): Matthew Green, Mani Modayil Korah, Husain Mithaiwala, Allen Wright, Klaus Lackner

Keywords(s): Environmental, Fuel Cells, Energy

Category(s): Physical Science, Environmental, Environmental Remediation/Wastewater Treatment, Manufacturing/Construction/Mechanical

Spotter-Free Weightlifting System

A Safer Way To Exercise Alone At Home & In The Gym THE PROBLEM Due to busy lifestyles and external forces such as pandemics, an increasing number of people are choosing to exercise at home or in 24-hour gyms. As such, there is a growing desire among weightlifters to perform bench-press exercises at their leisure without a spotter; however, the...

Published: 10/2/2024 | Inventor(s): Michael Esco, Will Wright

Keywords(s):

Category(s): Technology Classifications > Lifestyle & Leisure

Infection Control System for Resuscitation and Airway Management

Application Collapsible, single-use ‘pop-up tent’ system to prevent transmission of infectious disease during resuscitation and airway management. Key Benefits Provides protective barrier to prevent transmission of infectious disease. Allows adequate access to the patient for airway management procedures. Single-use to minimize infection...

Published: 7/30/2024 | Inventor(s): Adam Klein, Russell Gore, David Wright

Keywords(s): COVID19, Hospital and Surgery, Microbiology/Infectious Diseases

Category(s): TechPub Algolia > Medical Device

Self-Repairing Metal Matrix Composite

Composite Alloy Capable of Self-Repairing Large-Scale Cracks That Have Propagated During the Component’s Service LifeThis metal matrix composite is a heat-respondent, self-repairing alloy that repairs stress and fatigue cracks without needing skilled technicians and direct access. Metallic materials, such as aluminum alloys, are used in both the...

Published: 6/27/2021 | Inventor(s): Michele Manuel, Charles Fisher, Clara Wright

Keywords(s): liquid assisted, self-healing alloy, Shape memory alloy

Category(s): Technology Classifications > Engineering > Materials

Advanced Electrospray Emitter

UC Case No. 2019-862SUMMARYUCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a novel electrospray emitter with improved emitter geometry, extended operational stability, and improved thrust efficiencies.BACKGROUNDElectrospray devices use electricity to disperse charged molecules for a variety of applications including...

Published: 2/14/2025 | Inventor(s): Richard Wirz, Peter Wright

Keywords(s):

Category(s): Electrical > Electronics & Semiconductors, Materials > Fabrication Technologies, Mechanical > Aeronautics & Aerospace

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