Search Results - elaine+jaffe

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Molecular Classification of Primary Mediastinal Large B Cell Lymphoma Using Formalin-Fixed, Paraffin-Embedded Tissue Specimens

Abstract: Primary mediastinal B-cell lymphoma (PMBCL) is an aggressive type of non-Hodgkin lymphoma that mostly occurs in people between the ages of 30-40. It accounts for 5-7% of all aggressive lymphomas. The diagnosis of PMBCL is challenging as the histological features of PMBCL overlap with diffuse large B-cell lymphoma (DLBCL), another most common...

Published: 4/8/2024 | Inventor(s): Louis Staudt, Lisa Rimsza, David Scott, George Wright, Anja Mottok, Christian Steid, Elaine Jaffe, Randy Gascoyne, Elias Guerri, Elias Guerri, Elias Guerri, Andreas Rosenwald, Kai Fu, Timothy Greiner, Erlend Smeland, Jan Delabie, Rita Braziel, Wing Chan, Joo Song, Dennis Weisenburger, German Ott, James Cook

Keywords(s): assay, Diffuse Large B Cell Lymphoma, DLBCL, FFPE, Formalin-fixed, GENE EXPRESSION, paraffin-embedded biopsies, PMBCL, Primary Mediastinal Large B Cell Lymphoma, Staudt

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Diagnostics

Clinical Outcome Predictors for Mantle Cell Lymphoma

Abstract: Mantle cell lymphoma (MCL) is a group of aggressive B-cell lymphomas displaying heterogeneous outcomes after treatment. Some patients have the slowly progressing disease that does not require immediate treatment, while others have a disease that rapidly progresses despite highly aggressive treatment. A number of prognostic tools have been...

Published: 8/14/2024 | Inventor(s): Louis Staudt, David Scott, George Wright, Andreas Rosenwald, Pau Abrisqueta, Rita Braziel, Elias Guerri, Wing Chan, Joseph Connors, Diego Villa, Kai Fu, Randy Gascoyne, Timothy Greiner, Elaine Jaffe, Graham Slack, James Cook, Jan Delabie, German Ott, Lisa Rimsza, Dennis Weisenburger, Anja Mottok, Pedro Jares

Keywords(s): B-cell lymphomas, Gene expression profile, Mantle cell lymphoma, Prognostic tool

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Diagnostics, TherapeuticArea > Oncology

Methods for Identifying, Diagnosing, and Predicting Survival of Lymphomas

The present invention discloses methods for identifying, diagnosing, and predicting survival in a lymphoma or lymphoproliferative disorder on the basis of gene expression patterns. The invention discloses a novel microarray, the Lymph Dx microarray, for obtaining gene expression data from a lymphoma sample. The invention also discloses a variety of...

Published: 5/7/2024 | Inventor(s): Richard Fisher, George Wright, Sandeep Dave, Bruce Tan, Louis Staudt, John Powell, Wyndham Wilson, Elaine Jaffe, Wing Chan, Timothy Greiner, Dennis Weisenburger, James Armitage, Kai Fu, Lisa Rimza, Thomas Miller, Thomas Grogan, Elias Campo Guerri, Silvia Bea, Itziar Salaverria, Armando Lopez-Guillermo, Emilio Montserrat Costa, Victor Moreno, Andreas Zettl, German Ott, Hans-Konrad Muller-Hermelink, Andreas Rosenwald, Julie Vose, Randy Gascoyne, Joseph Connors, Erlend Smeland, Stein Kvaloy, Harald Holte, Jan Delabie, Andrew Lister

Keywords(s):

Category(s): Diagnostic

Survival Predictor For Diffuse Large B Cell Lymphoma

This invention provides methods and arrays related to a gene expression-based survival predictor for DLBCL patients, including patients treated with the current standard of care, which includes chemotherapy and the administration of Rituximab. The invention provides a method of predicting the survival outcome of a subject suffering from diffuse large...

Published: 5/7/2024 | Inventor(s): Richard Fisher, Lisa Rimza, Andrew Lister, Dennis Weisenburger, Jan Delabie, Erlend Smeland, Harald Holte, Stein Kvaloy, Rita Braziel, Pedro Jares, Armando Lopez-Guillermo, Elias Campo Guerri, Elaine Jaffe, Georg Lenz, Wyndham Wilson, George Wright, Sandeep Dave, Randy Gascoyne, Joseph Connors, Hans-Konrad Muller-Hermelink, Andreas Rosenwald, German Ott

Keywords(s):

Category(s): Diagnostic