Search Results - tijay+chung

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Method and Apparatus for Efficient TLS Revocation Mechanism
THE CHALLENGE: The widespread adoption of Transport Layer Security (TLS) is crucial for ensuring secure communication over the internet. TLS secures the connection between users and online services, protecting sensitive information during transmission. A vital aspect of TLS security is certificate revocation, which invalidates compromised or untrusted...
Published: 11/12/2024   |   Inventor(s): Tijay Chung
Keywords(s):  
Category(s): Technology Classifications > Software
Use of VDAC inhibitor, VBIT4, as a Treatment for Lupus
This technology includes a small molecule drug (VDAC inhibitor, also known as VBIT4) that may be useful for inhibiting lupus disease. To test lupus animal model, VBIT4 was continuously administered for 5 weeks to mice and there was no mortality or clinical symptoms in these animals. Additionally, VBIT4 treatment blocked the development of skin lesions...
Published: 1/8/2025   |   Inventor(s): Jeonghan Kim, Jay Chung, Varda Shoshan-Barmatz
Keywords(s):  
Category(s): Application > Therapeutics, Collaboration Sought > Licensing, TherapeuticArea > Immunology
Novel Roles of a DNA Repair Protein, DNA-PKcs, in Obesity, Neurological Function, and Aging
The catalytic subunit of the DNA-dependent protein kinase complex (DNA-PKcs) has been shown to be important in DNA repair and VDJ recombination in lymphocytes. The inventors have discovered that DNA-PKcs also plays novel, important roles in energy regulation and neurological function. The inventors observed that mature DNA-PKcs-deficient mice (also...
Published: 10/28/2024   |   Inventor(s): Jay Chung
Keywords(s): Aging, ANXIETY, Cardiovascular, depression, DIABETES, DNA-Dependent, DNA-PKcs, Endurance, Energy, HEART, IB1XXX, IB3XXX, IB6XXX, IBXXXX, Inflammation, insulin, INSULIN-DEPENDENT, IXXXXX, LEARNING, MEMORY, METABOLIC, Metabolism, Mitochondria, Neurological, OBESITY, REGULATION, TYPE-2, Weight
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Diagnostics, Application > Research Materials, Application > Vaccines, Application > Therapeutics, TherapeuticArea > Cardiology, TherapeuticArea > Reproductive Health, TherapeuticArea > Immunology
Chromatin Insulator Protecting Expressed Genes of Interest for Human Gene Therapy or Other Mammalian Transgenic Systems
The technology provides the isolation of a functional DNA sequence comprising a chromatin insulating element from a vertebrate system and provides the first employment of the pure insulator element as a functional insulator in mammalian cells. The technology further relates to a method for insulating the expression of a gene from the activity of cis-acting...
Published: 10/28/2024   |   Inventor(s): Jay Chung, Gary Felsenfeld
Keywords(s): CB2XXX, CBXXXX, CXXXXX
Category(s): Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Therapeutics