Search Results - vincent+rotello

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Polymeric Nanoparticle-Based Antibiofilm Therapy
PRODUCT OPPORTUNITIES • Antimicrobial ointment for topical treatments • Antimicrobial injectable for in vivo treatments • Antibiofilm therapy ADVANTAGES • Non-antibiotic based • High efficacy against both planktonic bacteria and more drug-resistant bacterial biofilms •...
Published: 6/7/2024   |   Inventor(s): Vincent Rotello, Ryan Landis, Akash Gupta
Keywords(s):  
Category(s): Healthcare, Life Sciences, Biotechnology, Therapeutics & prevention
A Simple Method for Making Biocompatible Protein Films as Antimicrobial Coatings
PRODUCT OPPORTUNITIES• Antimicrobial coatings• Antifouling coatings for implantable medical devices• Drug-releasing antimicrobial films or coatings for wound healing or in-dwelling devices• Protein films or coatings for directed cell adhesion and growth and for tissue engineeringADVANTAGES • Simple...
Published: 9/11/2023   |   Inventor(s): Vincent Rotello, Li-Sheng Wang, Sanjana Gopalakrishnan
Keywords(s):  
Category(s): Healthcare, Life Sciences, Engineering, Biotechnology
Nanoparticle-Stabilized Microcapsules for Effective Treatment of Bacterial Biofilms
PRODUCT OPPORTUNITIES• Antimicrobial ointments and creams for treatments of infected wounds• Antimicrobial toothpaste, mouthwash and dental floss• Disinfectants for biomedical surfacesADVANTAGES• Stable and biocompatible microcapsules • Highly potent in biofilm inhibition and eradication •...
Published: 8/10/2023   |   Inventor(s): Vincent Rotello, Bradley Duncan, Xiaoning A/k/a Sharlene Li
Keywords(s):  
Category(s): Healthcare, Life Sciences, Nanotechnology, Therapeutics & prevention
Polymeric Nanocapsules for the Treatment of Biofilms
PRODUCT OPPORTUNITIES• Antimicrobial injectables for in vivo treatments of pathogenic biofilms• Antimicrobial ointments and creams for topical treatments of pathogenic biofilms• Antimicrobial toothpaste, mouthwash and dental flossADVANTAGES• Stable and potent antimicrobial polymeric nanocapsules containing...
Published: 8/10/2023   |   Inventor(s): Vincent Rotello, Ryan Landis, Akash Gupta, Yiwei Lee
Keywords(s):  
Category(s): Biotechnology, Healthcare, Life Sciences, Nanotechnology, Therapeutics & prevention
Efficient Cytosolic Delivery of siRNA Using Nanoparticle-Stabilized Nanocapsules
PRODUCT OPPORTUNITIES• Novel delivery vehicle for the development and delivery of RNAi-based therapeutics• Advanced tool for life science, drug discovery or biomedical research• Efficient intracellular nucleic acid delivery systemADVANTAGES• New mechanism of siRNA delivery that allows for efficient and rapid...
Published: 8/10/2023   |   Inventor(s): Vincent Rotello, Ying Jiang, Rui Tang
Keywords(s):  
Category(s): Biotechnology, Life Sciences, Healthcare, Research tools, Therapeutics & prevention
Stable, Biocompatible and “Green” Protein Films for Antifouling, Antimicrobial and Tissue Engineering Applications
PRODUCT OPPORTUNITIES • Antimicrobial catheters • Implantable biomedical devices having antifouling coatings • Antifouling coatings for marine equipment • Drug-releasing antimicrobial films or coatings for wound healing or in-dwelling devices • Protein films or coatings for directed cell...
Published: 8/10/2023   |   Inventor(s): Vincent Rotello, Bradley Duncan, Li-Sheng Wang, Eunhee Jeoung, Chandramouleeswaran Subramani, Krishnendu Saha
Keywords(s):  
Category(s): Biotechnology, Environmental, Engineering, Healthcare, Life Sciences
An Efficient Intracellular Delivery Vehicle for the CRISPR/Cas9 Gene Editing System and Other Proteins
PRODUCT OPPORTUNITIES • Novel delivery vehicle for the development of revolutionary CRISPR/Cas9-based therapeutic methods to treat genetic diseases • Advanced tool for life science, drug discovery or biomedical research • Efficient intracellular protein delivery system ADVANTAGES • A general...
Published: 8/10/2023   |   Inventor(s): Vincent Rotello, Rubul Mout
Keywords(s):  
Category(s): Biotechnology, Healthcare, Life Sciences, Research tools, Nanotechnology, Therapeutics & prevention
Nanoparticle-Textured Surfaces for Highly Selective Adhesion, Sensing and Separation
This technology provides novel, engineered surfaces containing functionalized nanoparticle adhesive elements whose surface arrangements are optimized for highly selective adhesion, sensing and separation of biological or nonbiological analyte particles in a broad range of sizes, from submicron to tens of microns. The nanoparticle- textured surfaces...
Published: 8/3/2023   |   Inventor(s): Maria Santore, Jun Zhang*, Vincent Rotello
Keywords(s):  
Category(s): Material science, Devices & sensors, Nanotechnology, Research tools