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Search Results - technology+classifications+%3e+medical+%3e+infectious+diseases
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Cell Wall Protein 6 (Cwp6) as a Vaccine Component Against Clostridioides difficile Infection
Advantages Broader protection: targets bacterial colonization in addition to toxins A (TcdA) and B (TcdB) Applicability across different C. diff strains: Cwp6 is conserved across various C.diff ribotypes and toxinotypes Dual immune response: administration of Cwp6 with alum adjuvant elicits both systemic and IgG and mucosal IgA antibody responses Summary C.difficile...
Published: 9/29/2025
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Inventor(s):
Xingmin Sun
,
Lubem Agbendeh
Keywords(s):
Category(s):
Technology Classifications > Medical > Biotechnology
,
Technology Classifications > Medical > Infectious Diseases
FLR: A Triple-Target Fusion Vaccine Candidate Against Clostridioides difficile
Advantages Multi-Antigen Targeting for Broad Protection: targets three distinct virulence factors (FliC, LP2, RBD2) simultaneously Targeting Hypervirulent Strain Pathogenesis Significant protection from infection and weight loss Reduced fecal toxin and spore levels Summary Clostridioides difficile (C. difficile) is a bacterium that colonizes...
Published: 9/29/2025
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Inventor(s):
Xingmin Sun
Keywords(s):
Infectious Diseases Treatment
,
Vaccines
Category(s):
Technology Classifications > Medical > Pharmaceuticals
,
Technology Classifications > Medical > Infectious Diseases
,
Technology Classifications > Medical > Biotechnology
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Technology Classifications > Medical > Biomedical Engineering
Novel Anti- Aggregation Therapeutic Targets Against Cystic Fibrosis Caused by Pseudomonas Aeruginosa
Advantages: Therapeutic Targets: Identified essential genes in Pa aggregate formation that can be potentially targeted with therapeutics Improved Infection Model: use of synthetic CF sputum media that closely mimics the physical and nutritional environment of CF sputum Potential for Broader Applications: can be extended to other bacterial species...
Published: 10/14/2025
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Inventor(s):
Sophie Darch
Keywords(s):
Medical Devices
,
Medical Diagnostics
,
Therapeutics
Category(s):
Technology Classifications > Medical > Biotechnology
,
Technology Classifications > Medical > Infectious Diseases
,
Technology Classifications > Medical > Therapeutics
,
Technology Classifications > Medical > Medical Diagnostics
Antibacterial-Modified Comet Assay for the Study of Genome Integrity in Bacterial Pathogenesis
Advantages: The modified comet assay delivers consistent, reproducible results, ensuring reliable data for bacterial pathogenesis and DNA damage/repair studies A cost-effective and user-friendly antimicrobial peptide, making the modified comet assay an economical solution The method is versatile, applicable to bacteria, mammalian cells, microbiome,...
Published: 10/14/2025
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Inventor(s):
Marcus Cooke
,
Haley Lockhart
Keywords(s):
Category(s):
Technology Classifications > Medical > Biotechnology
,
Technology Classifications > Medical > Infectious Diseases
,
Technology Classifications > Medical > Medical Diagnostics
Mecamylamine as a Therapeutic Agent for SARS-CoV-2
Advantages: A new method of treating severe acute respiratory syndrome (SARS-CoV-2) Mecamylamine, a nicotinic receptor antagonist, blocks virus and nAChR receptor binding and decreases SARS-COV-2 replication in virus-infected Calu-3 cells Mecamylamine decreases cytokine expression in MHV4-infected IMG cells and manages inflammatory conditions Mecamylamine...
Published: 9/24/2024
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Inventor(s):
Paul Sanberg
,
Christian Brechot
Keywords(s):
Respiratory Diseases Treatment
Category(s):
Technology Classifications > Medical > Infectious Diseases
Methods for Treating Covid-19 Based on Individual Genomic Profiles
Advantages: A high-throughput method offers a rapid and efficient way to predict severe outcomes in COVID-19 patients, facilitating faster clinical decision-making for pulmonary injury. Can be integrated with clinical variables to improve triage across healthcare settings, potentially reducing hospital stays, and optimizing resource allocation...
Published: 7/16/2024
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Inventor(s):
Jose Herazo-Maya
,
Brenda Juan-Guardela
,
Gaetane Michaud
Keywords(s):
Category(s):
Technology Classifications > Medical > Infectious Diseases
,
Technology Classifications > Medical > Respiratory
,
Technology Classifications > Medical > Therapeutics
An Automatic System of Tagging and Uploading of Mosquito Species from Smartphone Images
Competitive Advantages Cloud-based system Real-time identification and reporting Minimal to zero human intervention is required Time and cost savings Improved accuracy Summary Our inventors have developed a method for automatic identification of mosquito genus, species, and anatomy from smart-phone images. The method involves anyone (including...
Published: 6/26/2024
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Inventor(s):
Sriram Chellappan
,
Pratool Bharti
,
Mona Minakshi
,
Willie McClinton
,
Jamshidbek Mirzakhalov
Keywords(s):
Category(s):
Technology Classifications > Energy & Environment
,
Technology Classifications > Medical > Infectious Diseases
,
Technology Classifications > Software
Methods and Techniques to Classify Stages in the Gonotrophic Cycle of Mosquitoes from Images using Computer Vision Techniques
Advantages: Enables rapid and accurate identification of mosquito gonotrophic stages, enhancing disease surveillance efforts effectively. Reduces the need for extensive entomological expertise, making mosquito monitoring more accessible and efficient. Facilitates integration with citizen-science platforms, empowering community involvement...
Published: 10/14/2025
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Inventor(s):
Sriram Chellappan
,
Farhat Azam
,
Ryan Carney
,
Sherzod Kariev
Keywords(s):
Artificial Intelligence
,
Infectious Diseases
,
Predictive Analytics
Category(s):
Technology Classifications > Medical > Infectious Diseases
,
Technology Classifications > Data/AI > D/AI Imaging
,
Technology Classifications > Computer Science > Algorithms
Regulated Delivery of Antibiotic and Antifungal Drugs Via Controlled Degradable Chondroitin Sulfate Particles
Advantages: Novel synthesis of Chondroitin sulfate (CS) particles for encapsulation of antibiotic and antifungal drugs. Synthesis can be fine-tuned to produced non-degradable, slightly degradable, and completely degradable CS drug carriers, for a variety of therapeutic applications. CS particles were successfully tested for encapsulation...
Published: 10/14/2025
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Inventor(s):
Nurettin SAHINER
,
Ramesh Ayyala
Keywords(s):
Drug Delivery and Nanomedicine
,
Pharmaceuticals
Category(s):
Technology Classifications > Medical > Cell & Tissue Engineering
,
Technology Classifications > Medical > Infectious Diseases
,
Technology Classifications > Medical > Therapeutics
,
Technology Classifications > Medical
Receptor Binding Domain 2 of CDTb Component of the Clostridioides Difficile Binary Toxin CDT as a Vaccine Component Against C. Difficile Infection
Advantages: Enhanced Vaccine Conservation: This technology ensures the conservation of critical vaccine components across diverse C. difficile strains, improving vaccine effectiveness. Immunogenic Potential: RBD2, a key discovery, exhibits exceptional immunogenicity, promising robust immune responses in vaccine recipients. Inhibition of CDT...
Published: 9/3/2024
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Inventor(s):
Xingmin Sun
,
Shaohui Wang
Keywords(s):
Infectious Diseases
,
Vaccines
Category(s):
Technology Classifications > Medical > Infectious Diseases
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