Search Results - technology+classifications+%3e+human+health+care+%3e+therapeutics

111 Results Sort By:
Cancer Cell-Targeting Salmonella Strains for Cancer-Specific Treatment
Cancer-Targeting Engineered Bacteria Directly Attacks Tumors and Stimulates Immune Defenses This cancer-targeting Salmonella platform delivers therapeutic proteins directly to cancer tissue, reducing the growth of a tumor or regressing it. Cancer ranks as the second most common cause of death in the United States. Bacteria have been used to target...
Published: 12/5/2025   |   Inventor(s): Roy Curtiss, Shifeng Wang
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Therapeutics
Bruton's Tyrosine Kinase (BTK) Inhibitors as Antiviral Agents via Inflammasome Blockade
Proactively Mitigates and/or Prevents EBV-Driven Malignancies in Immunosuppressed Patients This approach prevents EBV-associated malignancies by inhibiting the Epstein-Barr virus (EBV) lytic phase malignancies. EBV is a ubiquitous oncogenic herpesvirus, causing an estimated 300,000 new cancers and 200,000 deaths each year. EBV commonly causes infectious...
Published: 12/5/2025   |   Inventor(s): Sumita Bhaduri-McIntosh, Michael McIntosh
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Therapeutics
Gene Therapy for Comprehensive Treatment of Degenerative Muscle Diseases
Combines Two Transgenes in a Single AAV Vector to Target Multiple Tissues This adeno-associated virus gene therapy is designed to address both cardiac and skeletal muscle dysfunction in degenerative muscle diseases by combining two transgenes in a single AAV vector, a significant improvement over conventional approaches that require separate viral...
Published: 11/6/2025   |   Inventor(s): Hugh Sweeney, Margaret Sleeper
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Therapeutics, Technology Classifications > Human Health Care > Others
Efficient Genome Editing Tool Using CODE Systems for Precise Modifications
Complements Existing Prime Editors to Expand Toolbox for Genome Manipulations This precision-driven genome editing tool uses chimeric oligonucleotide-directed editing (CODE) to replace, insert, or delete specific genes with exceptional accuracy. The genome editing market, valued at nearly $10 billion in 2024 and anticipated to grow to $25 billion by...
Published: 10/9/2025   |   Inventor(s): Piyush Jain, Noah Rakestraw, Briana Pizzano, Cameron Myhrvold, Long Nguyen
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Therapeutics, Technology Classifications > Research Tools > Therapeutics
Gene Therapy Cargo Delivery System Across Multinucleated Cells
A Nucleic Acid Delivery Platform Enables Expression of Fusion Proteins Across Multinucleated Cells This delivery platform enables the shuttling of engineered proteins throughout all nuclei in multinucleated cells with direct application to gene therapy. Gene therapy has emerged as one of the most promising frontiers in modern medicine, offering potential...
Published: 10/9/2025   |   Inventor(s): Eric Wang, Keril Poukalov, Zane Zeier
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Therapeutics, Technology Classifications > Research Tools > Therapeutics
Synthetic Mucus to Reduce Inflammation in Inflammatory Bowel Disease (IBD)
Reinforcing the Gut’s Natural Defenses to Reduce Inflammation and Improve Gastrointestinal Health This synthetic mucin mimics the natural mucus barrier in the gut, reinforcing the protective layer and improving gut health. Mucins are the key proteins that form the protective mucus layer in the gut and other mucosal tissues. In disorders such...
Published: 10/2/2025   |   Inventor(s): Luiz Roesch, Brent Sumerlin, Greg Sawyer
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Therapeutics
SPLICER: Small Molecule-Inducible Gene Expression Switches
Enables Ligand-Inducible Regulation of Gene Expression or Knockdown This small molecule-inducible gene expression based on riboswitches (SPLICER) enables precise, drug-responsive control of gene expression for safer and more flexible gene and cell therapies. In mammalian cells, alternative splicing greatly expands the diversity of RNA sequences. These...
Published: 9/2/2025   |   Inventor(s): Eric Wang, Yu Zhou
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Therapeutics, Technology Classifications > Research Tools > Therapeutics
Autoregulated MBNL Gene Therapy for Myotonic Dystrophy
Next-Generation Gene Therapy Vectors with Tunable, Tissue-Specific, and Auto-Regulated Expression for Superior Safety and Efficacy This technology introduces recombinant adeno-associated virus (rAAV) vectors engineered to enable precise, regulated expression of therapeutic genes. Recombinant viruses can deliver therapeutic gene expression constructs...
Published: 9/2/2025   |   Inventor(s): Eric Wang, Andy Berglund, Elizabeth Delgado, Jana Jenquin, Derek Muscato, Ona McConnell, Leanne Adams, Maria Valero Quiros
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Therapeutics, Technology Classifications > Research Tools > Therapeutics
Alternative Splicing Cassettes for AAV Gene Therapy Regulation
Uses Tissue-Specific Exons for Precise Control Therapeutic Cargo Delivery These alternative splicing cassettes use tissue specific exons to precisely deliver adeno-associated virus (AAV) cargo. AAVs are a commonly used gene therapy vector for delivering genetic material into cells. Current technology relies upon tissue specific promoters to guide and...
Published: 9/30/2025   |   Inventor(s): Eric Wang, Keril Poukalov
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Therapeutics, Technology Classifications > Research Tools > Therapeutics
Silk Fibroin from Plodia Interpunctella and Methods for Creating Biomaterial Scaffolds
A Tunable Biomaterial Platform for Biomaterial Fabrication and Regenerative Applications Silk fibroin is a well-established biomaterial known for its strength, biocompatibility, and biodegradability. Biopolymers are investigated for biomaterial fabrication as an alternative to synthetic polymers, reducing the production of environmental pollutants...
Published: 7/14/2025   |   Inventor(s): Whitney Stoppel, Lauren Eccles, Bryce Shirk, Marisa Pacheco, Elizabeth Aikman, Jasmine McTyer
Keywords(s):  
Category(s): Technology Classifications > Engineering > Materials, Technology Classifications > Medical Devices > Others, Technology Classifications > Human Health Care > Therapeutics
1 2 3 4 5 6 7 8 9 10 ...