Search Results - technology+classifications+%3e+1.+life+science+%3e+drug+delivery

13 Results

Sort By:

METHODS OF MAKING GELS AND FILMS USING CURLI NANOFIBERS

INV-21044 Background The curli system is the primary structural component of bacterial biofilm that promotes bacterial adhesion. This system is composed of highly robust amyloid nanofibers that have self-assembly properties and high resistance to harsh environmental conditions. Such unique properties make these nanofibers attractive for the production...

Published: 9/10/2024 | Inventor(s): Neel Joshi

Keywords(s):

Category(s): Technology Classifications > 2. Physical Science > Environmental/Clean tech, Technology Classifications > 1. Life Science > Bioengineering/Tissue Engineering, Technology Classifications > 1. Life Science > Drug Delivery

Injectable, Bioadhesive Cryogel Scaffolds for Biomedical Uses

INV-19031 Background In the US, over 27 million hospital visits include invasive, therapeutic surgeries. However, despite substantial advances in gelatin, fibrin, and cyanoacrylate-based biomaterial adhesives, a robust solution with tissue integration, biomechanical integration, and wet-tissue adhesion remains a significant challenge. Hydrogels and...

Published: 9/10/2024 | Inventor(s): Devyesh Rana, Sidi Bencherif, Nasim Annabi

Keywords(s):

Category(s): Technology Classifications > 1. Life Science > Therapeutics, Chemistry, Technology Classifications > 1. Life Science > Drug Delivery

Oxygen as an immunological adjuvant or co-adjuvant to reinforce vaccines and immunotherapies

INV-21019 Background Vaccines are crucial to fight infections, cancer, and autoimmune conditions as they aid in generating immune response before the onset of the disease. Vaccines developed with purified molecules often do not stimulate an effective immune response as compared to the immune response generated against natural infection. Hence, adjuvants...

Published: 9/10/2024 | Inventor(s): Sidi Bencherif, Thibault Colombani

Keywords(s): Adjuvant, Biomaterials, Co-adjuvant, Oxygen, Vaccines

Category(s): -Pharmaceutical Composition, Technology Classifications > 1. Life Science > Therapeutics, Technology Classifications > 1. Life Science > Drug Delivery

Cationic Polymers as Co-Drugs for chemotherapeutic Agents

Normal;border-collapse: collapse; } INV-17100 Background There are numerous anticancer chemotherapies available in the market that show cytotoxic effects along with unwanted various side effects. Researchers are trying to induce desired clinical effects at lower concentrations without much success as lowering the drug concentration has led to...

Published: 9/10/2024 | Inventor(s): Debra Auguste, Daxing Liu

Keywords(s):

Category(s): -Health, -Pharmaceutical Composition, Technology Classifications > 1. Life Science > Therapeutics, Chemistry, Technology Classifications > 1. Life Science > Drug Delivery

Hygroscopic Molecules Inhibit Collagen Nucleation

INV-20080 Background Collagen serves as the premier, load-bearing molecule in humans and animals, and is one of the major building blocks of bones, skin, muscles, tendons, and ligaments. This abundant protein helps to support and repair damaged tissue. However, the medical community has struggled to fully leverage the power of collagen for use...

Published: 10/15/2024 | Inventor(s): Jeffrey Paten

Keywords(s): Hygroscopic molecule, Nucleation Inhibitor, Proteoglycan - Glycosaminoglycan - Saccharide, Regeneration, Threshold concentration

Category(s): -Biomedical Materials, -Pharmaceutical Composition, Technology Classifications > 2. Physical Science > Advanced materials/Nanomaterials, Technology Classifications > 1. Life Science > Drug Delivery

Nanopreparation for Co-Delivery of Drugs and siRNA

INV-13004 Background Overexpression of p‑glycoprotein (encoded by MDR1 gene) is often associated with multidrug-resistant cancer. This protein leads to drug resistance by the efflux of chemotherapeutic drugs from the cancerous cells. Small interfering RNA (siRNA), also known as post-transcriptional gene silencer, can suppress the expression of specific...

Published: 9/10/2024 | Inventor(s): Vladimir Torchilin, Swati Biswas

Keywords(s): Delivery, Drug Delivery, Healthcare Innovation, Medical, Nanomedicine, Nanotechnology, Pharmaceutical Composition, Therapeutic

Category(s): -Nanotechnology, -Nanomedicine, -Pharmaceutical Composition, -Health, Technology Classifications > 1. Life Science > Therapeutics, Technology Classifications > 1. Life Science > Drug Delivery

Making Oligonucleotides Better Biopharmaceuticals with Brush Polymer-Assisted Compaction

INV-16006 Background Oligonucleotide-based gene therapy holds tremendous promise for treating a variety of disorders with a genetic basis, including cancers, neurological diseases, and metabolic conditions. However, due to difficulties including poor accumulation at target sites, removal by immune responses, nuclease degradation, and low biochemical...

Published: 10/15/2024 | Inventor(s): Ke Zhang, Xueguang Lu

Keywords(s):

Category(s): -Chemistry, -Cancer, Technology Classifications > 1. Life Science, Technology Classifications > 1. Life Science > Biotechnology, Technology Classifications > 1. Life Science > Drug Delivery

Biodegradable Implant for Sustained Trans-Nasal Delivery to the Brain

INV-20104 Background Central Nervous System (CNS) diseases refer to those groups of neurological disorders particularly affecting the central nervous system comprised of the brain and spinal cord. They arise due to multiple factors such as neurodegeneration, infections leading to potential damage, trauma, metabolic disorders, tumor, stroke etc....

Published: 11/6/2024 | Inventor(s): Mansoor Amiji, Smrithi Padmakumar, Benjamin Bleier

Keywords(s): Biomedical implants, Neurological Disease, Pharmaceutical Composition, Therapeutic

Category(s): -Materials, Technology Classifications > 1. Life Science > Therapeutics, Technology Classifications > 1. Life Science, Technology Classifications > 1. Life Science > Bioengineering/Tissue Engineering, Technology Classifications > 1. Life Science > Drug Delivery

Green-synthesized tellurium nanowires for the growth of metallic nanoparticles on top

INV-18120 Background Traditional physicochemical approaches for the synthesis of compounds, drugs, and nanostructures are developed either as potential solutions for antimicrobial resistance or to fight against cancer. Nevertheless, these approaches have several limitations, such as the use of toxic chemicals and the production of toxic by‑products...

Published: 9/10/2024 | Inventor(s): Thomas Webster, Ada Crua, David Medina Cruz

Keywords(s):

Category(s): -Cancer, Diagnostics, Technology Classifications > 1. Life Science > Drug Delivery

Oxygen Releasing Cryogels

INV-18108 Background Hydrogels have been used for several biomedical applications because of their three dimensional nature, high water content, and wide range of polymers that can be used for their fabrication. Hydrogels as 3D scaffolds have recently gained momentum because they can mimic key features of the extracellular matrix, which is mainly...

Published: 9/10/2024 | Inventor(s): Sidi Bencherif, Thibault Colombani, Michail Sitkovsky, Adnan Memic, Stephen Hatfield

Keywords(s):

Category(s): Technology Classifications > 1. Life Science, Antimicrobial, Technology Classifications > 1. Life Science > Bioengineering/Tissue Engineering, Technology Classifications > 1. Life Science > Drug Delivery

1 2