Search Results - shaolei+wang

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Blocking Necroptosis in Kidney Transplantation: PPP1R3G Targeting to Improve Graft Function and Survival
Advantages Novel Mechanism: Identifies PPP1R3G as a previously unexplored regulatory node in necroptosis during kidney transplantation. Demonstrated Preclinical Efficacy: In animal models, inhibition of PPP1R3G signaling resulted in a ~65% reduction in plasma creatinine and a ~55% improvement in glomerular filtration rate (GFR). Peptidomimetic...
Published: 1/13/2026   |   Inventor(s): Lei Wang, Zhigao Wang, Jianfeng Cai
Keywords(s): Organ Transplantation, Renal / Kidney
Category(s): Technology Classifications > Medical > Biotechnology, Technology Classifications > Chemistry, Technology Classifications > Medical > Therapeutics
A ligand-assisted mineral dissolution process for accelerating and optimizing CO2 mineralization in alkaline rocks
This technology uses formate-based ligands to speed up the extraction of calcium and magnesium from rocks, enabling faster, more energy-efficient carbon capture and storage by turning CO2 into stable minerals without harsh chemicals or intensive grinding. Background The field of carbon capture and storage (CCS) is critical in the global effort to...
Published: 1/13/2026   |   Inventor(s): Ryosuke Okuno, Hao Wang, Omar Carrasco Jaim, Upali Weerasooriya
Keywords(s):  
Category(s): Physical sciences > Environmental & sustainable solutions > Carbon capture, utilization & storage
A methodology for efficient CO2 capture using organic carbonates
Background The field of carbon capture technology is crucial in addressing the growing concerns over climate change and the increasing concentration of carbon dioxide (CO2) in the atmosphere. Traditional energy production methods, particularly those reliant on fossil fuels, release significant amounts of CO2, contributing to global warming. As industries...
Published: 1/13/2026   |   Inventor(s): Ryosuke Okuno, Upali Weerasooriya, Omar Carrasco Jaim, Hao Wang, Hassan Amer
Keywords(s):  
Category(s): Physical sciences > Environmental & sustainable solutions > Carbon capture, utilization & storage
VITRUALGENOME, A VIRTUAL REALITY IMMERSIVE SYSTEM
VAlue proposition A virtual reality immersive system that enables users to visualize, explore, and analyze 3D genomes and their associated biochemical features. Combining VirtualGenome with Tensor-FLAMINGO and 3DVarientVision creates a technology that provides a high-resolution image of the altered 3D structure resulting from a genetic variant, decodes...
Published: 4/9/2025   |   Inventor(s): Jianrong Wang, Andre Popovitch, Hao Wang
Keywords(s):  
Category(s): Biotechnology, Computer Software, Education & Training
HIGH-RESOLUTION RECONSTRUCTION OF SINGLE-CELL 3D CHROMOSOMAL STRUCTURES
VAlue proposition The dynamic 3D spatial structure of chromosomes has variations across cells of different types and between cells of the same type. This structural variation between single cells plays an important role in regulating single-cell specific transcription and epigenetic landscapes. Computationally reconstructing chromosomal 3D structure...
Published: 12/22/2025   |   Inventor(s): Jianrong Wang, Jianliang Qian, Hao Wang
Keywords(s):  
Category(s): Biotechnology, Computer Software
A Self-Assembled Implantable Microtubular Pacemaker for Wireless Cardiac Electrotherapy (Case No. 2024-059)
Summary: UCLA researchers in the Department of Bioengineering have developed a novel implantable microtubular pacemaker for reliable and comfortable pacing for patients with arrythmias. Background: Cardiac pacemakers are essential devices used to manage abnormal heart rhythms, or arrythmias, by sending electrical pulses to prompt the heart to beat...
Published: 3/26/2025   |   Inventor(s): Tzung Hsiai, Shaolei Wang
Keywords(s): arrhythmia, Cardiac Electrophysiology, cardiovascular monitoring, central venous pressure (CVP), Continuous blood pressure monitoring, critical care, heart failure, hemodynamic monitoring, image signal processing, implantable sensors, medical device cardiac monitoring, non-invasive monitoring, pulmonary arterial pressure (PAP), wearable
Category(s): Medical Devices, Medical Devices > Monitoring And Recording Systems, Electrical, Electrical > Flexible Electronics, Medical Devices > Hospital Systems, Medical Devices > Cardiac
Cryogenic Propellant Storage Tank Chill-Down and Filling for Refueling in Microgravity and Reduced Gravity Environments
Uses Spray Cooling with Flow Pulsing to Prevent the Unnecessary Boiling of Cryogenic Propellant Film in Microgravity and Reduced Gravity Environments This storage tank and propellant transfer apparatus conserves valuable cryogenic propellants in reduced gravity and microgravity environments. The extension of human space exploration is NASA’s...
Published: 1/20/2026   |   Inventor(s): Jacob Chung, Jason Hartwig, Hao Wang, Bo-Han Huang, Jun Dong
Keywords(s):  
Category(s): Technology Classifications > Engineering > Mechanical, Technology Classifications > Engineering > Chemical
Wireless power transfer via partially magnetized pavement
Design concept of partially magnetized pavement layer​ Invention Summary: Lack of access to charging infrastructure and longer charging time have limited electric vehicle (EV) adoption. One promising solution is to utilize inductively coupled power transfer (ICPT)-based wireless charging modules embedded in the pavement for dynamic charging....
Published: 8/12/2025   |   Inventor(s): Hao Wang, Lukai Guo
Keywords(s):  
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Energy & Battery
Multiple-DOF energy harvester from vibrations
Cantilevers with 1, 2 and 3 degrees of freedom​ Invention Summary: Piezoelectric energy harvesters mounted on bridges, pavements and other transportation infrastructure can potentially replace batteries for powering autonomous sensors by converting ambient kinetic energy into electric energy. Due to complications and uncertainties of vibration...
Published: 9/12/2024   |   Inventor(s): Hao Wang, Lukai Guo
Keywords(s):  
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Sensors, Technology Classifications > Energy & Battery
Cell-permeant and water-soluble rhodamine dyes for quantitative imaging applications
Summary Rhodamines are a class of fluorescent proteins (FP) that stand out for their higher photostability and brightness as well as easier synthesis compared to other FPs; however, classic rhodamines generally have poor water solubility and tend to aggregate in an aqueous environment. Oregon Health & Science University researchers have developed...
Published: 9/21/2023   |   Inventor(s): Summer Dowell (Gibbs), Lei Wang, Antonio Montano
Keywords(s): Imaging, Imaging - Other, Research Tools, Research Tools - Reagents
Category(s): Imaging, Research Tools
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