Search Results - jianrong+wang

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VITRUALGENOME, A VIRTUAL REALITY IMMERSIVE SYSTEM
VAlue proposition A virtual reality immersive system that enables users to visualize, explore, and analyze 3D genomes and their associated biochemical features. Combining VirtualGenome with Tensor-FLAMINGO and 3DVarientVision creates a technology that provides a high-resolution image of the altered 3D structure resulting from a genetic variant, decodes...
Published: 4/9/2025   |   Inventor(s): Jianrong Wang, Andre Popovitch, Hao Wang
Keywords(s):  
Category(s): Biotechnology, Computer Software, Education & Training
HIGH-RESOLUTION RECONSTRUCTION OF SINGLE-CELL 3D CHROMOSOMAL STRUCTURES
VAlue proposition The dynamic 3D spatial structure of chromosomes has variations across cells of different types and between cells of the same type. This structural variation between single cells plays an important role in regulating single-cell specific transcription and epigenetic landscapes. Computationally reconstructing chromosomal 3D structure...
Published: 4/9/2025   |   Inventor(s): Jianrong Wang, Jianliang Qian, Hao Wang
Keywords(s):  
Category(s): Biotechnology, Computer Software
3DVARIENTVISION: DECODE FUNCTIONAL IMPACTS OF GENETIC VARIANTS BASED ON 3D CHROMATIN
VAlue proposition Deciphering the effects and mechanisms of genetic variants is essential to understand human genetics and further precision medicine. A genetic variant is a permanent change in the nucleotide sequence that makes up a gene, also known as a gene mutation. Mutations can cause diseases or phenotypic changes. Typically, Genome Wide Association...
Published: 4/9/2025   |   Inventor(s): Jianrong Wang, Jiaxin Yang
Keywords(s):  
Category(s): Medical, Biotechnology, Computer Software
PSM Peptides as Vaccine Targets Against Methicillin-Resistant Staphylococcus aureus
Available for licensing and commercial development are compositions and methods for the treatment and inhibition of Methicillin-resistant Staphylococcus aureus (MRSA), a dangerous human pathogen. The invention concerns immunogenic peptides that can be used to induce protective immunity against MRSA, including phenol-soluble modulin (PSM) peptides. In...
Published: 10/28/2024   |   Inventor(s): Rong Wang, Michael Otto
Keywords(s): Against, ANTIBIOTIC, AUREUS, CA-MRSA, DB3XXX, DBXXXX, DC4XXX, DCXXXX, DXXXXX, fasciitis, Gene, GenePeptides, Immunity, Immunogenic, Methicillin-resistant, MRSA, necrotizing, necrotizing fasciitis, Peptides, PMS, PSM, Staphloccus, STAPHYLOCOCCAL, Staphylococcus, Targets, Vaccine
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Vaccines, Application > Therapeutics, TherapeuticArea > Infectious Disease
2020-945 Epitaxy-Enabled Substrate Transfer
SUMMARYUCLA researchers in the Department of Materials Science and Engineering have developed a cost-effective and damage-free method to transfer a selective-area doping structure from one substrate to another via epitaxy.BACKGROUNDDoping is ubiquitous throughout consumer electronics. Doped GaN (Gallium Nitride) is particularly useful owing to the ultra-high...
Published: 2/14/2025   |   Inventor(s): Ya-Hong Xie, Jia Wang, Hiroshi Amano
Keywords(s):  
Category(s): Materials > Functional Materials, Materials > Semiconducting Materials, Materials > Nanotechnology, Electrical > Electronics & Semiconductors, Electrical > Sensors
2017-380 DEVICE AND METHOD FOR MICROSCALE CHEMICAL REACTIONS
Device and Method for Microscale Chemical ReactionsTech ID: 30291 / UC Case 2017-380-0SUMMARYUCLA researchers in the Departments of Bioengineering and Molecular and Medical Pharmacology have developed a passive microfluidic reactor chip with a simplified design that is less costly than existing microfluidic chips.BACKGROUNDAlthough positron emission...
Published: 2/14/2025   |   Inventor(s): Michael van Dam, Jia Wang
Keywords(s): Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Medical Imaging, PET
Category(s): Diagnostic Markers, Medical Devices > Medical Imaging, Platforms > Diagnostic Platform Technologies, Medical Devices > Medical Imaging > PET
Bi-Functional RGD Peptide and a Co-Signaling Mechanism to Promote Therapeutic Angiogenesis
Bi-Functional RGD Peptide to Promote Therapeutic Angiogenesis, Treat Ischemic Diseases Technology: While previous studies have focused on the identification of biological ligands to improve the functions of endothelial cells, MUSC and Clemson University researchers have combined modern bioinformatics and a newly established peptide functionalized...
Published: 3/23/2023   |   Inventor(s): Chung-Jen (James) Chou, Ying Mei, Jia Jia
Keywords(s):  
Category(s): BioPharma
Advanced Engineered Formulations of TMP/Ligustrazine and Microparticle/Nanoparticle Formulations for Inhalation Drug Delivery for Lung Vascular, Interstitial and Airway Diseases
This invention formulates Tetramethylpyrazine (TMP) in a readily deliverable aerosol to treat pulmonary hypertension and other lung diseases. Background: Pulmonary hypertension (PH) is a condition that involves high blood pressure in the arteries of the lungs. Veins stiffen and narrow, making blood flow more difficult and thus, increased pressure...
Published: 11/16/2023   |   Inventor(s): Heidi Mansour, Jason Yuan, Jian Wang, Alexan Gomez, Priyadarshini Muralidharan, Yali Gu
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary, Technology Classifications > Life Sciences > Drug Delivery, Technology Classifications > Life Sciences > Therapeutics