Search Results - jorvani+cruz+villarreal

3 Results Sort By:
Laser Capture Microdissection (LCM) Microfluidic Platform for Single-Cell Proteomic Analysis
Single-cell proteomics is an emerging field for proteomic analyses of individual cells. Single-cell genomic analyses have greatly expanded our understanding of cell heterogeneity and disease progression; however, protein identification and quantitative cell-to-cell variation provide a deeper level of understanding of the biological regulators in the...
Published: 6/28/2023   |   Inventor(s): Alexandra Ros, Jorvani Cruz Villarreal, Ana Egatz-Gomez, Todd Sandrin, Paul Coleman
Keywords(s):  
Category(s): Proteomic Assays/Reagents/Tools, Neurodegenerative Disease Technologies, Life Science (All LS Techs), Bioanalytical Assays, Chemistries & Devices
3D-Printed Microfluidic Device Featuring Electronically Triggered Droplet Generation and Injection for Serial Crystallography
Background Serial femtosecond crystallography (SFX) with recent advances in X-ray free electron lasers (XFELs) is a revolutionary technique for determining the structure of macromolecules at ambient temperature. It has enabled the study of large membrane protein complexes at atomic resolution and their reaction dynamics, previously considered impossible...
Published: 2/23/2023   |   Inventor(s): Alexandra Ros, Daihyun Kim, Diandra Doppler, Jorvani Cruz Villarreal, Richard Kirian, Reza Nazari, Sahir Gandhi
Keywords(s):  
Category(s): Chemical/Biological Sensors, Bioanalytical Assays, Chemistries & Devices, Physical Science, Manufacturing/Construction/Mechanical
Co-Flow Injection for Serial Crystallography Using a 3D-Printed Hybrid Nozzle/T-Junction Device
Background Serial femtosecond crystallography (SFX) with X-ray free electron lasers (XFELs) has enabled crystal structure determination of reaction intermediates at ambient temperatures. Unlike traditional crystallography, where a single crystal is irradiated as it rotates, SFX usually involves the injection of a continuous stream of randomly oriented...
Published: 2/23/2023   |   Inventor(s): Alexandra Ros, Daihyun Kim, Austin Echelmeier, Jorvani Cruz Villarreal, Diandra Doppler, Richard Kirian, Reza Nazari
Keywords(s):  
Category(s): Physical Science, Bioanalytical Assays, Chemistries & Devices, Manufacturing/Construction/Mechanical, Chemical/Biological Sensors