Search Results - ana+egatz-gomez

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Droplet Injector for Time-Resolved Crystallography with XFELs
Background Protein X-ray crystallography has become one of the most successful structural biology techniques since the first three-dimensional structure of myoglobin, a protein, was revealed. Many important scientific discoveries have been made using X-ray crystallography, including understanding insulin’s mechanism of action, mass production...
Published: 1/19/2024   |   Inventor(s): Alexandra Ros, Diandra Doppler, Mukul Sonker, Ana Egatz-Gomez, Richard Kirian, Sahba Zaare, Abhik Manna, Konstantinos Karpos, Roberto Alvarez
Keywords(s):  
Category(s): Physical Science, Bioanalytical Assays, Chemistries & Devices, Imaging
Laser Capture Microdissection (LCM) Microfluidic Platform for Single-Cell Proteomic Analysis
Single-cell proteomics is an emerging field for proteomic analyses of individual cells. Single-cell genomic analyses have greatly expanded our understanding of cell heterogeneity and disease progression; however, protein identification and quantitative cell-to-cell variation provide a deeper level of understanding of the biological regulators in the...
Published: 6/28/2023   |   Inventor(s): Alexandra Ros, Jorvani Cruz Villarreal, Ana Egatz-Gomez, Todd Sandrin, Paul Coleman
Keywords(s):  
Category(s): Proteomic Assays/Reagents/Tools, Neurodegenerative Disease Technologies, Life Science (All LS Techs), Bioanalytical Assays, Chemistries & Devices
Modular 3D Printed Devices for Sample Delivery
­Background Microfluidic devices are commonly used in serial crystallography applications. In most serial crystallography experiments, the sample molecules are formed into droplets through electrical stimulation, then injected into a focused beam of electrons or X-rays so their structure can be analyzed. The various components of the experiment...
Published: 2/23/2023   |   Inventor(s): Alexandra Ros, John Spence, Diandra Doppler, Garrett Nelson, Richard Kirian, Reza Nazari, Ana Egatz-Gomez, Mukul Sonker, Mohammad Rabbani
Keywords(s):  
Category(s): Physical Science, Bioanalytical Assays, Chemistries & Devices
Scalable Method for Continuous Synthesis of Upconverting Nanoparticles
Background Upconverting nanoparticles (UCNPs) are materials that absorb infrared light and emit in the ultraviolet-visible-near infrared (UV-NIR) range. Thus, there is a large Stokes shift between excitation and emission, with no overlap. UCNPs—which typically include a NaYF4 or NaGdF4 matrix doped with other lanthanides—can be used for...
Published: 2/23/2023   |   Inventor(s): Ana Egatz-Gomez, Alexandra Ros
Keywords(s):  
Category(s): Advanced Materials/Nanotechnology, Imaging, Medical Imaging, Physical Science