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Search Results - methods
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Treatment of Polycystic Kidney Disease using Muscarinic Acetylcholine Receptor Modulators
Project ID: TECH2026-01 Background Polycystic Kidney Disease (PKD) affects 1 in 500 people. Half of PKD of patients reach kidney failure by age 50. Annual U.S. healthcare costs exceed $120 billion. There is currently no cure and a few affective treatments. Autosomal dominant polycystic kidney disease (ADPKD) is a genetic disorder characterized by...
Published: 3/13/2026
|
Inventor(s):
Wissam AbouAlaiwi
,
Lubna Alshriem
Keywords(s):
Category(s):
Methods
,
Rare Disease
A Comprehensive Security Orchestration, Automation, and Response System (SOAR) for Connected and Autonomous Vehicles (CAVs)
Connected and autonomous vehicles (CAVs) rely heavily on software, connectivity, and automation—expanding the cyber-attack surface and creating new safety and reliability risks. Key threats include distributed denial of service (DDoS) attacks that can trigger operational failures, man-in-the-middle attacks that can intercept or compromise communications,...
Published: 2/13/2026
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Inventor(s):
Niyomdi Magani
,
Jared Oluoch
Keywords(s):
Category(s):
Methods
Method for Processing Reactive/Nonreactive Materials Using Binder Agent
Novel Binding Agent Removal Process Background Existing binder jetting processes struggle with completely removing the binder, which leads to residual carbon that affects product quality. Residual carbon, originating from the binder, poses significant challenges, particularly for reactive materials such as nickel-titanium ((NiTi) alloys and for other...
Published: 2/12/2026
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Inventor(s):
Mohammad Pourshams
,
Mohammad Elahinia
,
Behrang Poorganji
Keywords(s):
Category(s):
Methods
,
Materials
Fully Automated Fraction Collection Instrument
Project ID: TECH-2023-10 Background Size exclusion chromatography (SEC) is the preferred method to isolate and purify exosomes and extracellular vesicles. However, this technique is labor-intensive, requiring the operator to pipette samples, buffer, and wash into individual columns. Current solutions attempt to automate fraction collection, but still...
Published: 8/28/2024
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Inventor(s):
Shi-He Liu
Keywords(s):
Category(s):
Methods
,
Device
Advanced Driving Assistance System Using Fuzzy Logic
Project Id: D2022-24 Connected autonomous vehicles need an enhanced understanding of driver behavior to address complications and challenges around safety and efficiency of these self-driving vehicles and the driver. The Society of Automotive Engineers (SAE) has classified self-driving vehicles into stages, which range from level 0 to 5. Particularly,...
Published: 5/9/2024
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Inventor(s):
Devinder Kaur
,
Tejaswi Kakarala
Keywords(s):
Category(s):
Methods
LC/MS for Microcystin Separation and Analysis
Project ID: D2016-76 Background When water conditions are favorable for cyanobacteria growth, harmful algae blooms (HABs) can result, causing elevated levels of toxins called microcystins (MCs). There are over 300 microcystin variants. The EPA suggests that MC-LR variant concentration in drinking water should be less than 0.3 µg/L. Trace levels...
Published: 10/2/2025
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Inventor(s):
Dragan Isailovic
,
Dirukshika Palagama
,
Raymond West
Keywords(s):
Category(s):
Methods
Emulsion Formation using corona discharge and electrohydrodynamic pumping
Project ID: D2020-22 Background Making water-in-oil emulsions often requires high pressure, ultrasonication, or sensitive inversion techniques that may still only result in a semi-stable colloid. In addition to emulsion shelf life, these techniques have drawbacks, such as having high-energy consumption and narrow/sensitive production parameters, needing...
Published: 2/18/2026
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Inventor(s):
Hossein Sojoudi
,
Mohcen Shahbaznezhad
,
Amir Dehghanghadikolaei
Keywords(s):
corona discharge
,
Emulsion
,
encapsulation
,
ionic wind
,
Plasma
,
water-in-oil
Category(s):
Manufacturing
,
Materials
,
Methods
,
Tools
Adenovirus Survivin for Detection or Treatment of Uterine Leiomyosarcoma
The Current State of Art Uterine sarcoma, though with very low incidence (4% of uterine cancer), has a high malignant degree and poor prognosis. Leiomyosarcoma is the most common type of uterine sarcoma and usually occurs in women over 40 years. Proper differentiation between benign leiomyoma and malignant uterine leiomyosarcoma can dramatically improve...
Published: 5/25/2021
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Inventor(s):
Ayman Al-Hendy
,
Mostafa Khater
Keywords(s):
Category(s):
Diagnostics
,
Methods
,
Therapeutics
Method for Real-Time, Non-Invasive Intracranial Pressure Monitoring
The current state of the art The market for Brain function monitoring is growing rapidly as a result of the increased incidence of neurological and neurodegenerative disorders. At a CAGR of 6.2%, the market is estimated to grow from USD 6.3 billion to 8.6 billion. Problems with the current art The current
methods
of monitoring brain function have...
Published: 12/10/2025
|
Inventor(s):
Matthew Lyon
Keywords(s):
Category(s):
Medical Devices
,
Methods
Quantification by Ultrafiltration and Immunofixation Electrophoresis Testing (QUIET) for monoclonal serum free light chains
The current state of the art: Plasma cell myelomas is a plasma cell disorder that is associated with the presence of monoclonal immunoglobulin or fragments secreted by a B-cell clone. It can be detected and monitored by the presence of free monoclonal light chains. Currently, the serum free-light-chain (sFLC) assay is the most analytically sensitive...
Published: 4/7/2023
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Inventor(s):
Gurmukh Singh
,
Roni Bollag
Keywords(s):
Category(s):
Diagnostics
,
Methods
,
Research Tools
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