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Search Results - calcium
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Tumor Associated
Calcium
Signal Transducer 2 (TACSTD2)-Overexpressing Huh7.5 Cells That Are More Permissive to HCV Cell Entry and Replication Compared to the Model Huh7.5 Cell Line
Worldwide, 130-150 million individuals are chronically infected with hepatitis C virus (HCV), a major cause of liver-associated morbidity and mortality worldwide. Despite recent advances in antiviral drugs that can cure some individuals, a rapid decline of the global disease burden is hampered by remarkably high treatment costs and a high number of...
Published: 7/25/2024
|
Inventor(s):
Vandana Sekhar
,
Patrizia Farci
Keywords(s):
2
,
Associated
,
CALCIUM
,
Cells
,
Huh7.5
,
Signal
,
TACSTD2-overexpressing
,
TRANSDUCER
,
tumor
Category(s):
Collaboration Sought > Licensing
Development of genetically engineered probes for
calcium
sensing and manipulation
Calcium
levels in cells have critical functions. Moreover, calcium signaling plays a crucial role in the control of neuronal function and plasticity. Consequently, calcium sensing dysfunction can lead to a variety of pathological conditions such as Alzheimer’s disease or neuromuscular disorders such as Dystonia. Changes in neuronal Ca2+ concentration...
Published: 3/4/2024
|
Inventor(s):
Venkat Venkataraman
,
Anuradha Krishnan
,
Jeffrey Viviano
,
Jingyi Zhang
Keywords(s):
Alzheimer's
,
Calcium
,
Genetics
,
Neurology
,
Neuromuscular
Category(s):
Human Health Care > Therapeutics