Search Results - multiplex

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MULTI-MODAL, SAME-CELL ASSAY FOR SEQUENCING AND PROTEIN DETECTION

Researchers at UC Berkeley have developed a platform that enables unified proteomic and nucleic acid-based omics analysis from the same cell. Current multiplex assays, such as those relying on commercial systems like 10XGenomics, are limited in their ability to detect surface or intra-nuclear proteins and they require prior knowledge of target proteins...

Published: 10/23/2025 | Inventor(s): Amy Herr, Thi Thao Lam

Keywords(s): Multiplex, Nucleic Acid, Protein, Sequencing, Single Cell

Category(s): Technology Classifications > Biology

KINASE/PHOSPHATASTE SUBSTRATE ANALYSIS AND COMPOSITIONS USING SPECTRALLY ENCODED MICROBEADS

KINASE/PHOSPHATASTE SUBSTRATE ANALYSIS AND COMPOSITIONS USING SPECTRALLY ENCODED MICROBEADS Researchers at Stanford have developed a multiplexed bead-based dephosphorylation assay to allow for the measurement of multiple dephosphorylation reactions in one experiment. Post-translational modification involves the modification of proteins after...

Published: 9/14/2023 | Inventor(s): Polly Fordyce, Jamin Hein

Keywords(s): Lanthanide, Multiplex, Spectrally Encoded Beads

Category(s): Technology Classifications > Biology

MICROBEADS WITH RADIOMETRIC LANTHANIDE ENCODING FOR DRUG SCREENING

MICROBEADS WITH RADIOMETRIC LANTHANIDE ENCODING FOR DRUG SCREENING Researchers at Stanford have developed a new method of drug screening using lanthanide-encoded beads. Protein-protein interactions are one of the most fundamental biological processes which biomedical science has sought to engineer. Many currently available medications selectively...

Published: 12/19/2023 | Inventor(s): Polly Fordyce, Jamin Hein

Keywords(s): High Throughput Screening, Lanthanide, Multiplex, Spectrally Encoded Beads

Category(s): Technology Classifications > Biology

MASSIVELY SCALABLE VIRAL TESTING AND ASYMPTOMATIC SURVEILLANCE

MASSIVELY SCALABLE VIRAL TESTING AND ASYMPTOMATIC SURVEILLANCE Researchers at Stanford have developed a method called Identity Preserving Sample Multiplexing (IPSM) for the scaled up and rapid identification of SARS-CoV-2 positive subjects. At the beginning of the 2020 COVID-19 pandemic, reliably tracking SARS-CoV-2 among patients was a critical...

Published: 1/31/2025 | Inventor(s): Sandy Klemm

Keywords(s): Barcode, Ligation, Multiplex, Patients, qPCR, SARS-CoV-2 Testing, Viral RNA

Category(s): Technology Classifications > Biology

Real-time PCR Multiplex Assay for Detection of Bacterial Respiratory Pathogens in Clinical Specimens

CDC researchers have developed a single-tube, real-time PCR assay for the simultaneous detection of three bacterial respiratory pathogens (Mycoplasma pneumoniae, Chlamydiophila pneumoniae and Legionella spp.). The assay has an internal control testing for presence of human DNA. This four-plex real-time PCR assay could potentially become a routine screening...

Published: 10/28/2024 | Inventor(s): Agnes Warner, Kathleen Thurman, Jonas Winchell

Keywords(s): AA5XXX, AAXXXX, assay, AXXXXX, Bacterial, CDC Docket Import, CDC Docket Import CDC Prosecuting, DA3XXX, DAXXXX, Detection, DXXXXX, Multiplex, OID-NCIRD-DBD, PATHOGENS, PCR, REAL, respiratory, TIME

Category(s): Collaboration Sought > Licensing, Application > Diagnostics, TherapeuticArea > Infectious Disease

Methods and Composition for Identification of Variants of JC Virus DNA; An Etiologic Agent for Progressive Multifocal Leukoencephalopathy (PML)

JC Virus causes a fatal disease in the brain called progressive multifocal leukoencephalopathy (PML) that occurs in many patients with immunocompromised conditions. The finding of JCV DNA in the patients with neurological symptoms of PML is a diagnostic criterion and is needed to confirm the diagnosis of PML to rule out other neurological conditions....

Published: 10/28/2024 | Inventor(s): Caroline Ryschkewitsch, Eugene Major

Keywords(s): Chain, DA4BXX, DA4XXX, DAXXXX, DD1XXX, DDXXXX, DETECTS, DEXXXX, Distinguishes, DNA, DXXXXX, GENOTYPES, Multiplex, NON-PATHOGENIC, PATHOGENIC, polymerase, PRESENCE, REACTION, That, viral

Category(s): Collaboration Sought > Collaboration, Application > Diagnostics, Application > Research Materials, TherapeuticArea > Infectious Disease