Search Results - microbiology%2finfectious+diseases

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Frog Skin Peptides for Treatment of Human Influenza Viruses
Application A therapeutic peptide that treats Influenza A virus Key Benefits New method of action compared to antiviral drugs currently in use. Therapeutic peptide is virucidal against drug resistant strains. Market Summary Worldwide seasonal influenza epidemics can impact 5 – 15% of the population. The occurrence of vaccine mismatch...
Published: 7/30/2024   |   Inventor(s): Joshy Jacob, David Holthausen, Song Lee, Sanil George
Keywords(s): Biologic, Microbiology/Infectious Diseases
Category(s): TechPub Algolia > Therapeutics
Frog Skin Peptides for Treatment of Zika Viruses
Application A therapeutic peptide that treats Zika Virus. Key Benefits Potential therapeutic to fight against the growing threat of the Zika virus. Peptide is fast acting and destroys Zika virions within 5 minutes of exposure. Market Summary Zika is an infectious disease spread primarily by Aedes mosquitoes and results in symptoms similar to...
Published: 11/20/2024   |   Inventor(s): Joshy Jacob, Song Lee, David Holthausen, Sanil George
Keywords(s): Biologic, Microbiology/Infectious Diseases
Category(s): TechPub Algolia > Therapeutics
Infection Control System for Resuscitation and Airway Management
Application Collapsible, single-use ‘pop-up tent’ system to prevent transmission of infectious disease during resuscitation and airway management. Key Benefits Provides protective barrier to prevent transmission of infectious disease. Allows adequate access to the patient for airway management procedures. Single-use to minimize infection...
Published: 7/30/2024   |   Inventor(s): Adam Klein, Russell Gore, David Wright
Keywords(s): COVID19, Hospital and Surgery, Microbiology/Infectious Diseases
Category(s): TechPub Algolia > Medical Device
ADGRB3/BAI3 Knockout Mouse
ApplicationKnockout mouse models for adhesion G protein-coupled receptors B3, brain-specific angiogenesis inhibitor-3 (ADGRB3/BAI3) gene study.Technical SummaryEmory University researchers have developed a knockout mouse model for the ADGRB3/BAI3 gene. Mice were generated by CRISP/cas9 technology on C57Bl6 background. These mice can be used to study...
Published: 10/28/2024   |   Inventor(s): Erwin Van Meir
Keywords(s): Animal Model, COVID19, Microbiology/Infectious Diseases, Musculoskeletal, Neuroscience/Pain, Oncology
Category(s): TechPub Algolia > Research Tools
Antibodies for Zika and Dengue Viruses
Applications ELISA Western Blot Immunohistochemistry Specificity Human monoclonal Technical Summary Zika Virus (ZIKV) is a mosquito borne filovirus responsible for a 2016-2017 epidemic in North and South America. ZIKV nonstructural protein 1 (NS1) is a pathogenicity factor implicated in virus replication, host interaction and immune invasion....
Published: 7/30/2024   |   Inventor(s): Jens Wrammert, Mark Mulligan
Keywords(s): Antibody, Microbiology/Infectious Diseases
Category(s): TechPub Algolia > Diagnostics, TechPub Algolia > Research Tools
Respiratory Syncytial Virus Strain A2-2-20F
Application Strain of respiratory syncytial virus (RSV) for vaccine and therapeutic research and development. Key Benefits Higher early viral load. Induces greater necrotic airway damage and neurophil infiltration. Market Summary RSV is a highly contagious and ubiquitous virus that causes respiratory tract infections in individuals of all ages,...
Published: 9/26/2024   |   Inventor(s): Martin Moore
Keywords(s): Microbiology/Infectious Diseases, Respiratory
Category(s): TechPub Algolia > Research Tools
TaqMan Array Cards for Pneumococcal Detection and Serotyping
ApplicationDiagnostic for identifying Streptococcus pneumonia serotypes.Key BenefitsAllows for rapid detection and serotype identification of Streptococcus pneumonia infections.Market SummaryStreptococcus pneumonia (Spn) is a gram-positive bacteria and significant human pathogen responsible for most pneumonia cases. Typically, Spn resides asymptomatically...
Published: 7/30/2024   |   Inventor(s): Jorge Vidal Graniel, Fuminori Sakai, Lesley McGee, Velusamy Srinivasan
Keywords(s): Enzyme/Protein, Microbiology/Infectious Diseases
Category(s): TechPub Algolia > Diagnostics
Transgenic Mice for Studying Cell-Type Specific Immunity
ApplicationTransgenic mice expressing floxed mitochondrial antiviral-signaling protein (MAVS) for study of cell-type and tissue-specific immunity.Key BenefitsStudy cell-type and tissue-specific immunity.Can be crossed using CRE-recombinase system.Technical SummaryMitochondrial antiviral-signaling protein (MAVS) is a protein in humans that is encoded...
Published: 11/20/2024   |   Inventor(s): Mehul Suthar
Keywords(s): Animal Model, Immunology/Inflammation, Microbiology/Infectious Diseases
Category(s): TechPub Algolia > Research Tools
Repurposed Kinase Inhibitor for Treatment of Multidrug Resistant Tuberculosis
ApplicationProtein tyrosine kinase inhibitor (imatinib) used as a treatment to prevent multiple drug-resistant tuberculosis lethality and latent reactivation.Key BenefitsEffective against drug resistant strains of tuberculosis.May be used in combination with current first-line treatments of TB.Market SummaryTuberculosis (TB) is a chronic infectious...
Published: 10/28/2024   |   Inventor(s): Daniel Kalman
Keywords(s): Biologic, Microbiology/Infectious Diseases, Repurposed Drug
Category(s): TechPub Algolia > Drug Discovery, TechPub Algolia > Therapeutics
CXCR4 Antagonists for the Treatment of Cancer
Application Small molecules containing either the piperidine or piperazine core which act as antagonists to C-X-C chemokine receptor type 4 (CXCR4) and may be orally administered. Key Benefits Orally administered CXCR4 antagonists with diverse clinical applications in oncology. Mobilize white blood cells in mice in a dose-dependent manner. Cause...
Published: 11/20/2024   |   Inventor(s): Lawrence (larry) Wilson, Dennis Liotta, John Wiseman, Michael Natchus
Keywords(s): Microbiology/Infectious Diseases, Oncology, Small Molecule
Category(s): TechPub Algolia > Therapeutics, TechPub Algolia > Drug Discovery
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