Search Results - keji+zhao

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Bivalent Tn5 Complex and its Application to Map Enhancer-Promoter Interactions for Use in Diagnostics

This technology includes a new reagent, termed bivalent Tn5 complex, and applied it to mapping genome-wide enhancer-promoter interactions to be utilized for disease diagnostics. Chromatin structure is critical for regulating transcription in normal development and disease states. In particular, the interaction between enhancers and promotes are essential...

Published: 8/12/2024 | Inventor(s): Keji Zhao, Qingsong Tang

Keywords(s):

Category(s): Application > Diagnostics, Collaboration Sought > Licensing, ResearchProducts > Research Equipment

Identification of a Novel Parvovirus for Vaccine Development and Use as a Diagnostic Tool

This technology includes a procedure for novel virus identification in a variety of human specimens by solexa high-throughput sequencing, which allows for the screening a large number of clinical specimens for novel virus discovery in a highly efficient and relatively economical method. By using this technique, we have successfully identified a novel...

Published: 9/5/2024 | Inventor(s): Ning Zhi, Neal Young, Baoyan Xu, Keji Zhao, Gangqing Hu

Keywords(s):

Category(s): Application > Diagnostics, Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease

Single cell profiling of chromatin Occupancy and RNAs Sequencing (scPCOR-seq)

Cell-to-cell heterogeneity in gene expression is a widespread phenomenon, and may play important roles in cellular differentiation, function and disease development. Human Cell Atlas aims to profile gene expression in every single human cells. Recent studies have implicated a potential role of chromatin in the heterogeneity in gene expression. Understanding...

Published: 8/12/2024 | Inventor(s): Keji Zhao

Keywords(s):

Category(s): Application > Research Materials, Collaboration Sought > Licensing, Application > Diagnostics, TherapeuticArea > Oncology

Genome Wide DNase I Hypersensitive Sites Detection in Formalin-Fixed Paraffin-Embedded Single Cells

A method of detecting DNase I hypersensitive sites ((DHS) in a single cell or very small number of cells, including cells recovered from formalin-fixed paraffin-embedded (FFPE) tissue slides of patient samples. DHS has revealed a large number of potential regulatory elements for transcriptional regulation in various cell types. The application of...

Published: 4/8/2024 | Inventor(s): Qingsong Tang, Keji Zhao

Keywords(s): amplification, AMPLIFICATION-BASED, assay, CHROMATIN, DNase-Seq, Listed LPM Contreras as of 4/15/2015, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, Single-cell, TECHNIQUE, VCXXXX, WBXXXX, WIXXXX, XGXXXX, XHXXXX, YAXXXX, YBXXXX

Category(s): Collaboration Sought > Licensing, Application > Consumer Products, Application > Therapeutics, TherapeuticArea > Oncology, ResearchProducts > Research Equipment, Application > Diagnostics, Application > Research Materials

DNA Nanocaged Enzymes

Compartmentalization increases the overall activity and specificity of encapsulated enzymes by protecting the enzymes, maintaining a high concentration of enzymes and substrates, and promoting substrate channeling. While there have been artificial enzymatic particles that have been created using compartmentalization by virus-like proteins, liposomes,...

Published: 2/23/2023 | Inventor(s): Jinglin Fu, Hao Yan, Neal Woodbury, Zhao Zhao

Keywords(s): Bioanalysis, Catalysis, Enzymes

Category(s): Advanced Materials/Nanotechnology, Bioanalytical Assays, Chemistries & Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors

Controlled Vapor-phase ion-gating (VPIG) and ion capping of Nanomaterials

INV-17050 Background The investigation of charged particles is a fundamental aspect of several disciplines including physics, astronomy, atmospheric science, and geophysics, and, in addition to ion gauge based pressure metrology, forms a critical component of numerous advanced applications such as mass spectroscopy, plasma acceleration, oncology,...

Published: 9/10/2024 | Inventor(s): Swastik Kar, Ji Hao, Daniel Rubin, Yung Joon Jung

Keywords(s): Carbon nanotubes, nanoparticles

Category(s): -Materials, -Nanotechnology, Technology Classifications > 2. Physical Science > Electronics/Semiconductors

Vapour-phase gating induced single-ion detection in graphene and single-wall carbon nanotube networks

INV-17012 Background Miniaturized devices having ultrasensitive ion detection capability are useful as ion detectors in diverse applications, including detection of radioactive material or other sources of radiation, electron/ion beam calibration, monitoring of pressure or vacuum, and detection of energetic particles from outer space. Carbon nanotubes...

Published: 9/10/2024 | Inventor(s): Swastik Kar, Ji Hao, Yung Joon Jung

Keywords(s):

Category(s): -Materials, -Sensors tech