Search Results - jingbi+you

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Piperlongumine-Based PROTAC As Potent Anticancer Agent With Reduced Toxicity
Uses Piperlongumine as an E3 Ligase Ligand to Facilitate the Degradation of Cancer-Associated Proteins of Interest This naturally occurring compound with anti-cancer properties has the potential to revolutionize cancer treatment by providing tailored therapies with reduced side effects. Cancer remains a significant health issue in the United States,...
Published: 2/26/2025   |   Inventor(s): Guangrong Zheng, Daohong Zhou, Dongwen Lyu, Yaxia Yuan, Xingui Liu, Yufeng Xiao, Wanyi Hu, Jing Pei
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Therapeutics
Glycan Binding HTS Platform for Drug Development
Description This technology is an innovative glycan library platform for drug development. This is a DNA-encoded glycan library (DEGL) platform demonstrating higher content and throughput potential. Scientists can utilize this platform to identify and study specific glycan structures through unique DNA barcodes, facilitating drug screening and lead...
Published: 2/21/2025   |   Inventor(s): George Peng Wang, Muhammed Kondengaden, Aishwarya Parameswaran, Jing Song, Liuqing Wen, Huajie Zhang
Keywords(s):  
Category(s): Assay, Research Tool
Fabrication Method for Hexagonal Boron Nitride Layers
Computer memory devices may employ any of various mechanisms for storing data, e.g., using memory cells each of which may be programmed to be in any of two or more states. Non-volatile memory includes memory cells each of which operates by changing the resistance across an active switching layer, e.g., an insulator, through the formation of conductive...
Published: 2/13/2025   |   Inventor(s): Ivan Sanchez Esqueda, Jing Xie, Robert Nemanich, Ali Yekta
Keywords(s): Electronics, Fabrication, Materials and Electronics, Memory, Nanofabrication, Nanostructure, PS-Advanced Materials and Nanotechnology, Resistive Memory
Category(s): Advanced Materials/Nanotechnology, Physical Science, Semiconductors, Materials & Processes
COLD SINTERED MXENE CERAMICS
PAGE SUMMARY This technology introduces a novel method for integrating 2D materials into ceramics without high-temperature degradation, enhancing their electrical and mechanical properties. It was jointly developed by leading researchers Yury Gogotsi at Drexel University and Clive Randall at Penn State University and is available for licensing. Nanocomposites...
Published: 2/20/2025   |   Inventor(s): Yury Gogotsi, Babak Anasori, Benjamin Legum, Pavel Lelyukh, Jing Guo, Ke Wang, Clive Randall
Keywords(s):  
Category(s): Advanced Materials & Chemicals, MXenes
Rare-Earth-Element Free Yellow Phosphors for White Light-Emitting Diodes
​ Yellow phosphor emits white light when excited with the 460 nm blue lighting. The blue LED (left half; top) when coated with dispersed yellow phosphor (right half; top) emits white light. Invention Summary: Despite their low energy consumption and higher efficiency, white light-emitting diodes made of blue chip coupled with yellow phosphor...
Published: 12/4/2024   |   Inventor(s): Jing Li, Zhichao Hu, Qihan Gong
Keywords(s): Electronics, LEDs
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Polymers/Composites/Materials, Technology Classifications > Electronics/Semiconductor
Hybrid Lighting Phosphors with High Quantum Efficiency, and Enhanced Thermal and Photostability
​ This rare-earth element-free invention can be used in LEDs to generate the entire visible spectrum​ Invention Summary: The use of rare earth elements in the phosphor coating of light-emitting diodes (LEDs) and compact fluorescent lamps (CFLs) raises environmental...
Published: 12/4/2024   |   Inventor(s): Jing Li, Yang Fang, Wei Liu
Keywords(s): LEDs, Photonics and photovoltaics
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Polymers/Composites/Materials, Technology Classifications > Electronics/Semiconductor
Controlled Tunnel Gap Device for Sequencing Polymers
To reduce costs and increase the availability of personalized genomics new approaches to DNA sequencing are required. Nanopore sequencing is one proposed technique. In nanopore sequencing, DNA molecules are forced through a tiny aperture by electrophoresis. As the individual bases transit the nanopore, their identity can be determined, in theory, by...
Published: 2/13/2025   |   Inventor(s): Stuart Lindsay, Shuai Chang, Jin He, Peiming Zhang, Shuo Huang
Keywords(s): Bio-Technology
Category(s): Life Science (All LS Techs)
DNA Sequencing by Molecular Recognition and Nanoscale Manipulation of Single Molecules
The US Government’s pursuit of the “Thousand Dollar Genome” and the “X Prize” goal of even lower cost DNA sequencing are striking examples of the importance being assigned to advances in methods for the DNA sequencing of the human genome. The first technology that finally allows for truly routine genome sequencing will...
Published: 2/13/2025   |   Inventor(s): Stuart Lindsay, Colin Nuckolls, Jinyao Tang, Jin He, Peiming Zhang, Kevin Reinhart
Keywords(s):  
Category(s): Life Science (All LS Techs), Bioanalytical Assays, Chemistries & Devices, Proteomic Assays/Reagents/Tools
DNA Sequencing by Molecular Recognition and Nanoscale Manipulation of Single Molecules
The US Government's pursuit of the "Thousand Dollar Genome" and the "X Prize" goal of even lower cost DNA sequencing are striking examples of the importance being assigned to advances in methods for the DNA sequencing of the human genome. The first technology that finally allows for truly routine genome sequencing will open a new...
Published: 2/13/2025   |   Inventor(s): Stuart Lindsay, Jin He, Peiming Zhang, Kevin Reinhart
Keywords(s):  
Category(s): Life Science (All LS Techs), Bioanalytical Assays, Chemistries & Devices, Genomic Assays/Reagents/Tools
Interleukin-27 Producing B-Cell Population and Uses Thereof
Summary: The National Eye Institute (NEI) seeks research co-development partners and/or licensees to advance the production and uses of interleukin-27 (IL-27) producing B-regulatory cell (i27-Breg) therapy for immune related autoimmune disorders. These disorders include but are not limited, to age-related macular degeneration (AMD), graft-versus-host...
Published: 12/20/2024   |   Inventor(s): Charles Egwuagu, Jin Choi
Keywords(s):  
Category(s): Application > Therapeutics, Collaboration Sought > Collaboration, TherapeuticArea > Neurology, TherapeuticArea > Immunology, TherapeuticArea > Ear, Nose, & Throat, Collaboration Sought > Licensing
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