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Search Results - liuqing+wen
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Microneedle array coating technology for enhanced stability and targeted delivery of mRNA and biologics
A microneedle-based system uses cryogenically pre-cooled needles coated via thin-film freeze-coating to preserve mRNA stability, enabling efficient, multi-therapeutic intradermal delivery of temperature-sensitive drugs. Background The field of advanced drug delivery systems has grown substantially as the biomedical industry grapples with the complexities...
Published: 1/27/2026
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Inventor(s):
Zhengrong Cui
,
Michael Sandoval
,
Robert Williams
,
Drew Weissman
,
Qin Li
Keywords(s):
Category(s):
Life sciences > Therapeutics > Drug discovery
Transgenic Mouse Model for Marfan Syndrome Research
Description: A genetically modified mouse model carrying the FBN1Q2469X mutation enables advanced study of systemic Marfan Syndrome manifestations and therapeutic development. This innovative transgenic mouse model incorporates a mutation analogous to the human FBN1Q2467X gene mutation linked to Marfan Syndrome, resulting in fibrillin-1 deficiency...
Published: 12/23/2025
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Inventor(s):
Li Li
,
Shichao Wu
,
Jiawei Zhao
Keywords(s):
Category(s):
Technology Category > Research tools
,
Technology Category > Animal models
,
Technology Category > Biology
,
Technology Category > Diagnostic
Low-Cost High-Performance 3D LiDAR Imaging System
Description: This innovative 3D imaging system uses time-of-flight measurement of photons with a conventional global shutter CMOS camera to generate accurate distance data converted into brightness levels. It includes a laser source, camera, delay generator, master trigger, and electronic control unit (ECU) which together capture and average multiple...
Published: 12/16/2025
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Inventor(s):
Wen Li
,
Suk Kyoung Lee
,
Blessed Oguh
,
Sulaiman Abubakar
Keywords(s):
Category(s):
Technology Category > Automotive & Transportation
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Technology Category > Physical Sciences
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Technology Category > Image Analysis (Cameras & Software)
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Technology Category > Revolutionizing Mobility
Bioplatform to Identify and Characterize Pathogens and Therapies against Tuberculosis and Other Granulomatous Diseases.
Treatment for human tuberculosis (TB) and other granulomatous diseases would benefit from high- throughput screening (HTS)-compatible platform replicating physiological conditions in hallmark granuloma lesions. However, currently available screening platforms and 2-D and 3-D cell culture systems lack throughput and key features, and relevant microenvironments...
Published: 5/9/2025
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Inventor(s):
Suraj Sable
,
James Posey
,
Wen Li
,
Allison Kline
Keywords(s):
Category(s):
Application > Therapeutics
,
Application > Research Materials
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TherapeuticArea > Infectious Disease
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Collaboration Sought > Collaboration
,
Collaboration Sought > Licensing
Glycan Binding HTS Platform for Drug Development
Description This technology is an innovative glycan library platform for drug development. This is a DNA-encoded glycan library (DEGL) platform demonstrating higher content and throughput potential. Scientists can utilize this platform to identify and study specific glycan structures through unique DNA barcodes, facilitating drug screening and lead...
Published: 7/15/2025
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Inventor(s):
Peng Wang
,
Mohammed Kondengadan
,
Aishwarya Parameswaran
,
Jing Song
,
Liuqing Wen
,
Huajie Zhang
Keywords(s):
Category(s):
Assay
,
Research Tool
Heavy Metal Sensing
VALUE PROPOSITION Heavy metal pollution in soils is widespread in the world, resulting from both natural sources and human activities (e.g., mining and smelting, industrial emission, fossil fuel combustion, etc.). Due to their toxicity, bioaccumulation, and environmental persistence, elevated levels of heavy metals in the environment pose major threats...
Published: 10/21/2025
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Inventor(s):
Wen Li
,
Hasan Banna
,
James Siegenthaler
,
Mohammad Kafi Kangi
,
Tumi Olason
Keywords(s):
Category(s):
Agriculture
,
Analytical Instruments
,
Environment
,
Test and Measurement
DNA Methylation Barriers
In normal differentiated cells, most of the genome is densely methylated, except CpG islands near promoters of actively transcribed genes. Maintaining this boundary between unmethylated promoter-associated and adjacent methylated regions is crucial as loss of segregation can lead to disease. Unfortunately, it is not clear where these boundaries are,...
Published: 2/13/2025
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Inventor(s):
Li Liu
,
Jingmin Shu
Keywords(s):
Category(s):
Applied Technologies
,
Genomic Assays/Reagents/Tools
,
Life Science (All LS Techs)
,
Diagnostic Assays/Devices
Recovering Critical Elements from Acid Mine Drainage
THE CHALLENGE The demand for certain elements, such as Manganese (Mn), Cobalt (Co), and Nickel (Ni), has surged in recent years due to the rapid growth of battery production for electric vehicles and utility-scale energy storage. The United States government has deemed Co, Ni, and Mn critical elements, primarily because of the country’s high...
Published: 10/17/2025
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Inventor(s):
Wencai Zhang
,
Qi Li
,
Rick Honaker
Keywords(s):
Category(s):
Technology Classifications > Energy
,
Technology Classifications > Mining and Recycling
,
Technology Classifications
,
Technology Classifications > Chemicals/Materials
PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids
The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...
Published: 1/9/2026
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Inventor(s):
Payman Dehghanian
,
Shiyuan Wang
,
Li Li
Keywords(s):
Category(s):
Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment
Automatic Retinal Image Analysis System
[Licensing negotiation in progress] [Invitation for Expression of Interest - Deadline: 19 August 2016] Invention Ref. 11/MED/405 We are inviting expression of interest in commercializing the technology “Automatic Retinal Image Analysis System”, which has been developed by the Division of Biostatistics of the School of Public Health...
Published: 9/16/2024
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Inventor(s):
Chung Ying Benny ZEE
,
Jock-Wai Jack LEE
,
Qing Li
Keywords(s):
Category(s):
Diagnostics
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