Search Results - jianyang+liu

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Transgenic Mouse Model for Marfan Syndrome Research
Description: A genetically modified mouse model carrying the FBN1Q2469X mutation enables advanced study of systemic Marfan Syndrome manifestations and therapeutic development. This innovative transgenic mouse model incorporates a mutation analogous to the human FBN1Q2467X gene mutation linked to Marfan Syndrome, resulting in fibrillin-1 deficiency...
Published: 12/23/2025   |   Inventor(s): Li Li, Shichao Wu, Jiawei Zhao
Keywords(s):  
Category(s): Technology Category > Research tools, Technology Category > Animal models, Technology Category > Biology, Technology Category > Diagnostic
Hyperbranched Polyglycerol Encapsulated Proteins for Oral Protein Delivery (Case No. 2012-425)
Patent Abstract: Methods for modifying therapeutic agents such as therapeutic biomolecules, such as proteins for improved oral, rectal or transmucosal delivery, as well as compositions made using such methods and methods of administering such compositions to a subject, are disclosed. Specifically, the therapeutic agents are conjugated to hyperbranched...
Published: 12/1/2025   |   Inventor(s): Yunfeng Lu, Juanjuan Du, Jie Li, Yang Liu
Keywords(s):  
Category(s): Platforms > Drug Delivery
Enhancing Luminescent Properties of Vapor-Deposited Perovskite Films Through Vapor Exposure
The industry of perovskite materials has been highly sought out for next generation technology and devices. Perovskite thin films have been used in a large array of applications including light-emitting diodes (LEDs), solar cells, lasers and photodetectors. However, within recent years the widely existing defects (from significant intrinsic point defects...
Published: 10/1/2025   |   Inventor(s): Jian Li
Keywords(s):  
Category(s): Advanced Materials/Nanotechnology, Physical Science, Semiconductor Devices, Semiconductors, Materials & Processes
Multi-parametric Acoustic, Optical and Mechanical Imaging of Cervical Tissue Insufficiencies to Predict Preterm Birth
An enhanced image-guidance system that integrates ultrasound and photoacoustic into existing ablation systems to provide an enhanced image-guidance system for identification of cervical tissue changes during pregnancy and postpartum. Technology Summary Preterm delivery is a main cause of perinatal morbidity and mortality worldwide, which is associated...
Published: 10/1/2025   |   Inventor(s): Mohammad Mehrmohammadi, Sonia Hassan, Edgar Hernandez-Andrade, Yan Yan, Maryam Basij
Keywords(s): Driving Lifelong Health
Category(s): Technology Category > Women's Health, Technology Category > Medical Devices, Technology Category > Life Science, Technology Category > Imaging, Technology Category > Acoustics
Delaying Bloom in Crops via Jasmonic Acid Inhibitors
THE CHALLENGE The challenge of protecting deciduous fruit crops from spring frost lies in the lack of cost-effective, scalable, and environmentally sustainable solutions that align with both biological timing and unpredictable weather patterns. Traditional methods like frost fans, heaters, and sprinklers are not only expensive and energy-intensive...
Published: 6/25/2025   |   Inventor(s): Sherif Sherif, Jianyang Liu, Tabibul Islam
Keywords(s):  
Category(s): Technology Classifications > Agriculture
Revolutionizing surgical interventions: the steerable flexible curved-drilling robot (SFCR)
­The Steerable Flexible Curved-Drilling Robot (SFCR) is an innovative medical device designed to enhance precision in surgical drilling through complex bone structures. This cutting-edge technology features a dual-tube system with a flexible drive shaft, enabling controlled, curved drilling paths that navigate around obstacles like nerves and low-density...
Published: 1/13/2026   |   Inventor(s): Farshid Alambeigi, Yang Liu
Keywords(s):  
Category(s): Life sciences > Medical technology > Medical devices
DROPLET-ELECTROPHORESIS DEVICES AND RELATED METHODS
­DROPLET-ELECTROPHORESIS DEVICES AND RELATED METHODS Researchers at UC Berkeley have developed a novel method for comprehensively profiling the proteomes of single cells. Genomics (DNA) and transcriptomics (RNA) sequencing is one of the cornerstones of our modern-day understanding of the genetic blueprint of life. Furthermore, sequencing and...
Published: 4/22/2024   |   Inventor(s): Amy Herr, Yang Liu
Keywords(s): Microfluidics, Protein, Single Cell Analysis
Category(s): Technology Classifications > Engineering
DNA Methylation Barriers
In normal differentiated cells, most of the genome is densely methylated, except CpG islands near promoters of actively transcribed genes. Maintaining this boundary between unmethylated promoter-associated and adjacent methylated regions is crucial as loss of segregation can lead to disease. Unfortunately, it is not clear where these boundaries are,...
Published: 2/13/2025   |   Inventor(s): Li Liu, Jingmin Shu
Keywords(s):  
Category(s): Applied Technologies, Genomic Assays/Reagents/Tools, Life Science (All LS Techs), Diagnostic Assays/Devices
An OCT method to improve scleral lens fitting
Summary The current technology allows for accurate and objective 3-dimensional (3D) mapping of the external limbus, which could ultimately improve the process of scleral lens fitting. Technology Overview Rigid scleral lenses are difficult to fit to patients because they must rest on the eye but vault over the cornea and the limbus, which is the transition...
Published: 9/4/2025   |   Inventor(s): David Huang, Yan Li, Clara Llorens Quintana
Keywords(s): Imaging, Imaging - Other, Software, Software - Diagnostic/Detection
Category(s): Imaging, Software
High-Throughput Direct-Measurement of Telomere Length
Telomeres are linear chromosome end-capping repetitive DNA sequences. They serve to protect the ends of chromosomes from undesirable fusion events, thus integrity and length are crucial for stability. Natural attrition as well as mutations can affect telomere integrity and length resulting in chromosome instability, senescence, cell death and human...
Published: 2/13/2025   |   Inventor(s): Julian Chen, Yang Li, Dhenugen Logeswaran
Keywords(s):  
Category(s): Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Genomic Assays/Reagents/Tools, Life Science (All LS Techs), Medical Diagnostics/Sensors
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