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Search Results - biomaterials+%26+drug+delivery
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Dosing algorithm for continuous infusion anti-infectives administered as continuous infusions via CRRT solutions
PAGE TITLE Overview PAGE SUMMARY Researchers at Drexel University and NYU have developed an innovative method for preparing and delivering medications for patients undergoing dialysis, hemodialysis, or Continuous Renal Replacement Therapy (CRRT). Specifically, this algorithm for adding antibiotics or other drugs to dialysate solutions adjusts their...
Published: 2/18/2025
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Inventor(s):
Jeffrey Cies
,
Arun Chopra
Keywords(s):
Category(s):
Pharmaceuticals & Therapeutics
,
Digital Health & Healthcare IT
,
Medical Devices, Diagnostics & Biosensors
,
Biomaterials & Drug Delivery
Geometrically Dynamic Hydrogel-Based Chemically-Eluting Shunt Prosthesis
PAGE TITLE Geometrically Dynamic Hydrogel-Based Chemically-Eluting Shunt Prosthesis PAGE SUMMARY Congenital heart abnormalities such as hypoplastic left heart syndromereduce the flow of blood from the heart to the lungs, such that it does not carry sufficient levels of oxygen through the body. Complex surgeries shortly after birth are typically...
Published: 2/20/2025
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Inventor(s):
Randy Stevens
,
Kara Spiller
,
Samantha Cassel
,
Krianthan Govender
,
Steven Chopski
,
Amy Throckmorton
Keywords(s):
Category(s):
Pharmaceuticals & Therapeutics
,
Medical Devices, Diagnostics & Biosensors
,
Biomaterials & Drug Delivery
Echogenic Polymer microcapsules and nanocapsules and methods for production and use thereof
PAGE TITLEOverviewPAGE SUMMARY Methods for producing echogenic polymer microcapsules and nanocapsules for use in diagnostic imaging and delivery of bioactive compounds as well as targeted imaging and delivery to selected tissues and cells are provided. Compositions containing these echogenic polymer microcapsules and nanocapsules for use in diagnostic...
Published: 2/18/2025
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Inventor(s):
Margaret Wheatley
,
Dalia El-Sherif
Keywords(s):
Cancer therapeutic
Category(s):
Pharmaceuticals & Therapeutics
,
Medical Devices, Diagnostics & Biosensors
,
Biomaterials & Drug Delivery
Magnetic Gradient Targeting And Sequestering Of Therapeutic Formulations And Therapeutic Systems Thereof
PAGE TITLEOverviewPAGE SUMMARY A therapeutic system and a method that uses stents, and/or other implantable devices (104) for local delivery of a therapeutic agent is disclosed. A therapeutic formulation (102) may include particles of a biocompatible magnetic or magnetizable material that carry the therapeutic agent, or magnetically responsive cells....
Published: 2/19/2025
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Inventor(s):
Gennady (gary) Friedman
,
Robert Levy
,
Ivan Alferiev
,
Michael Chorny
,
Ilia Fishbein
,
Boris Polyak
,
Darryl Williams
Keywords(s):
Category(s):
Pharmaceuticals & Therapeutics
,
Medical Devices, Diagnostics & Biosensors
,
Biomaterials & Drug Delivery
Method to repair a damaged intervertebral disc through the use of a bioadhesive, thermogelling hydrogel
PAGE TITLE Overview PAGE SUMMARY The present invention is directed to a bioadhesive thermogelling hydrogel composition for repairing and/or augmenting an intervertebral disc. The bioadhesive thermogelling hydrogel composition can be cross linked with the surrounding tissue so as to potentially serve as a nucleus pulposus replacement or augmentation...
Published: 2/18/2025
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Inventor(s):
Anthony Lowman
,
Andrea Jennifer Vernengo
,
Meredith Hans
,
Nigel Smith
,
Garland Fussell
Keywords(s):
Category(s):
Medical Devices, Diagnostics & Biosensors
,
Biomaterials & Drug Delivery
Multifunctional nanoparticles for prevention and treatment of atherosclerosis
PAGE TITLE Overview PAGE SUMMARY Atherosclerosis is a chronic inflammatory disease of the artery wall and a major cause of cardiovascular disease, the leading cause of death in the US and many developed economies. The inflamed cells release free radicals that produce a strong local oxidative environment where low density lipoproteins (LDLs) are...
Published: 2/19/2025
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Inventor(s):
Yinghui Zhong
,
Jia Nong
,
Zhicheng Wang
Keywords(s):
Category(s):
Pharmaceuticals & Therapeutics
,
Medical Devices, Diagnostics & Biosensors
,
Biomaterials & Drug Delivery
Magnetically-controllable delivery system for therapeutic agents
PAGE TITLEOverviewPAGE SUMMARY A magnetic delivery system for delivering a magnetizable particle to a location in a body, the device includes a magnetizable object implanted in the body, wherein the magnetizable object includes a plurality of segments distributed throughout the magnetizable object and wherein the segments are configured to provide a...
Published: 2/19/2025
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Inventor(s):
Gennady (gary) Friedman
,
Benjamin Yellen
,
Kenneth Barbee
,
Zachary Forbes
Keywords(s):
Category(s):
Pharmaceuticals & Therapeutics
,
Medical Devices, Diagnostics & Biosensors
,
Biomaterials & Drug Delivery
Biocompatible, biodegradable polymer-based, lighter-than-water scaffold for bone tissue engineering
PAGE TITLEOverviewPAGE SUMMARY Successful clinical repair and regeneration of bone remain a significant challenge in orthopedic surgery. Currently, autografts are the clinically preferred grafting material for osseous repair and replacement. They are, however, limited in supply, restricted by anatomical incompatibilities and are often associated with...
Published: 2/18/2025
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Inventor(s):
Cato Laurencin
,
Helen Lu
,
Mohammed Yusuf Khan
,
Edward Botchwey
,
Elliot Levine
,
Solomon Pollack
Keywords(s):
Bone Tissue engineering
,
Orthopedic
Category(s):
Medical Devices, Diagnostics & Biosensors
,
Biomaterials & Drug Delivery
BIOTIN-AVIDIN CONTROLLED DELIVERY SYSTEMS
PAGE TITLEOverviewPAGE SUMMARY The application relates to the delivery of immunomodulatory molecules, including cytokines, to the situs of tissue scaffolds, and wounds including injuries.Commercialization Opportunities ---------------------------------------------- IP STATUSIntellectual Property and Development StatusUnited States Patent Filed-15/299,084...
Published: 2/19/2025
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Inventor(s):
Kara Spiller
Keywords(s):
Category(s):
Pharmaceuticals & Therapeutics
,
Biomaterials & Drug Delivery
Stabilized Ultrasound Contrast Agent
PAGE TITLE Overview PAGE SUMMARY Provided is a particle-stabilized ultrasound contrast agentn (UCA) and methods of preparing same. Also provided is a method for preparing a lyoprotected UCA, a freeze-dried lyoprotected UCA, and a reconstituted freeze-dried lyoprotected UCA. IP STATUS Intellectual Property and Development Status United States...
Published: 2/18/2025
|
Inventor(s):
Margaret Wheatley
,
Boriphat Methachan
,
Carl Solis
Keywords(s):
Category(s):
Pharmaceuticals & Therapeutics
,
Medical Devices, Diagnostics & Biosensors
,
Biomaterials & Drug Delivery
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