Search Results - pharmaceuticals+%26+therapeutics

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Glutamate Modulators to Treat Neurological and Psychiatric Disorders
PAGE TITLE Overview PAGE SUMMARY Prof. Sandhya Kortagere of Drexel University has developed glutamate transport modulators for treating neurological disorders caused by glutamate dysregulation. These small molecule drugs are a platform technology that increase clearance of the neurotransmitter glutamate by cells containing GLT-1, an important modulator...
Published: 2/19/2025   |   Inventor(s): Sandhya Kortagere
Keywords(s):  
Category(s): Pharmaceuticals & Therapeutics
The Power of Food Scale: A Tool to Evaluate the Psychological impact of the Food Environment Factors that Affect Appetite
PAGE TITLE Overview PAGE SUMMARY Executive Statement: Hunger in humans is driven by basic internal factors like nutritional or caloric deficit but also by external factors like the food environment. as well as more complex behaviors driven by pleasure or desire. The Power of Food Scale (PFS) is a validated measure of hedonic hunger, the...
Published: 2/19/2025   |   Inventor(s): Michael Lowe
Keywords(s):  
Category(s): Pharmaceuticals & Therapeutics, Research Tools & Materials
Dosing algorithm for continuous infusion anti-infectives administered as continuous infusions via CRRT solutions
PAGE TITLE Overview PAGE SUMMARY Researchers at Drexel University and NYU have developed an innovative method for preparing and delivering medications for patients undergoing dialysis, hemodialysis, or Continuous Renal Replacement Therapy (CRRT). Specifically, this algorithm for adding antibiotics or other drugs to dialysate solutions adjusts their...
Published: 2/18/2025   |   Inventor(s): Jeffrey Cies, Arun Chopra
Keywords(s):  
Category(s): Pharmaceuticals & Therapeutics, Digital Health & Healthcare IT, Medical Devices, Diagnostics & Biosensors, Biomaterials & Drug Delivery
Cyclic Peptide Triazole Dual Site Inhibitors of HIV-1 Envelope gp120 Glycoproteins
Cyclic Peptide Triazole Dual Site Inhibitors of HIV-1 Envelope gp120 Glycoproteins16-1930*, 14-1731*, and 09-1100PFaculty Inventors: Irwin Chaiken, Professor of Biochemistry & Molecular Biology and Adel Ahmed Rashad, Research Assistant Professor of Biochemistry & Molecular BiologyPAGE TITLECyclic Peptide Triazole Dual Site Inhibitors of HIV-1...
Published: 2/19/2025   |   Inventor(s): Irwin Chaiken
Keywords(s):  
Category(s): Pharmaceuticals & Therapeutics
Geometrically Dynamic Hydrogel-Based Chemically-Eluting Shunt Prosthesis
­ PAGE TITLE Geometrically Dynamic Hydrogel-Based Chemically-Eluting Shunt Prosthesis PAGE SUMMARY Congenital heart abnormalities such as hypoplastic left heart syndromereduce the flow of blood from the heart to the lungs, such that it does not carry sufficient levels of oxygen through the body. Complex surgeries shortly after birth are typically...
Published: 2/20/2025   |   Inventor(s): Randy Stevens, Kara Spiller, Samantha Cassel, Krianthan Govender, Steven Chopski, Amy Throckmorton
Keywords(s):  
Category(s): Pharmaceuticals & Therapeutics, Medical Devices, Diagnostics & Biosensors, Biomaterials & Drug Delivery
A Chimeric MSP-based Malaria Vaccine
PAGE TITLE A chimeric MSP-based malaria vaccine PAGE SUMMARY There are an estimated 200 million people infected with malaria annually, with an estimated 400,000-500,000 deaths, and 40% of the world’s population at risk of contracting the disease. While artemisinin and mosquito reduction are the current treatments, there are artemisinin-resistant...
Published: 2/19/2025   |   Inventor(s): James Burns
Keywords(s):  
Category(s): Pharmaceuticals & Therapeutics
Echogenic Polymer microcapsules and nanocapsules and methods for production and use thereof
PAGE TITLEOverviewPAGE SUMMARY Methods for producing echogenic polymer microcapsules and nanocapsules for use in diagnostic imaging and delivery of bioactive compounds as well as targeted imaging and delivery to selected tissues and cells are provided. Compositions containing these echogenic polymer microcapsules and nanocapsules for use in diagnostic...
Published: 2/18/2025   |   Inventor(s): Margaret Wheatley, Dalia El-Sherif
Keywords(s): Cancer therapeutic
Category(s): Pharmaceuticals & Therapeutics, Medical Devices, Diagnostics & Biosensors, Biomaterials & Drug Delivery
Magnetic Gradient Targeting And Sequestering Of Therapeutic Formulations And Therapeutic Systems Thereof
PAGE TITLEOverviewPAGE SUMMARY A therapeutic system and a method that uses stents, and/or other implantable devices (104) for local delivery of a therapeutic agent is disclosed. A therapeutic formulation (102) may include particles of a biocompatible magnetic or magnetizable material that carry the therapeutic agent, or magnetically responsive cells....
Published: 2/19/2025   |   Inventor(s): Gennady (gary) Friedman, Robert Levy, Ivan Alferiev, Michael Chorny, Ilia Fishbein, Boris Polyak, Darryl Williams
Keywords(s):  
Category(s): Pharmaceuticals & Therapeutics, Medical Devices, Diagnostics & Biosensors, Biomaterials & Drug Delivery
NOVEL GLUTAMATE TRANSPORTER ACTIVATORS AND METHODS USING SAME
PAGE TITLE Neuroprotective agent for Parkinson’s Disease PAGE SUMMARY Parkinson’s Disease (PD) is a progressive neurological disorder whose prevalence increases with age and certain genetic predispositions. It is estimated that 7-10 million people are affected by Parkinson’s Disease worldwide, with 1 million in the United States....
Published: 2/19/2025   |   Inventor(s): Sandhya Kortagere, Ole Mortensen, Andreia Mortensen, Joseph Salvino
Keywords(s):  
Category(s): Pharmaceuticals & Therapeutics
A new method to study and manipulate APP processing and amyloidogenesis
PAGE TITLE A new method to alter amyloid precursor protein processing and amyloidogenesis PAGE SUMMARY Altered Amyloid Precursor Protein (APP) processing and Aβ production have long been recognized as major factors in the cognitive decline associated with both Alzheimer’s Disease (AD) and HIV-Associated Neurocognitive Disorders (HAND)....
Published: 2/18/2025   |   Inventor(s): Olimpia Meucci, Renato Brandimarti
Keywords(s):  
Category(s): Research Tools & Materials, Pharmaceuticals & Therapeutics
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