Search Results - immunology%2finflammation

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Total Ankle Arthroplasty Design
Application An intra-articular alignment guide for ankle replacement system to treat ankle arthritis. Key Benefits Less invasive method that does not require drilling a hole through the heel for Inbone II tibial stem placement. More convenient to use compared to Inbone II frame and foot holder to find the correct alignment. Market Summary Approximately...
Published: 7/30/2024   |   Inventor(s): Rishin Kadakia
Keywords(s): Hospital and Surgery, Immunology/Inflammation
Category(s): TechPub Algolia > Medical Device
CIITA Deficient Human B Cell Line
Application Human B cell line deficient in class II transactivator (CIITA). Key Benefits Deficient in CIITA. Useful for expression of tranfected MHC-II genes and alleles. Technical Summary The class II transactivator (CIITA) is essential for the expression of major histocompatibility complex class II (MHC-II) genes. However, the role of CIITA...
Published: 9/26/2024   |   Inventor(s): Jeremy Boss, Christopher (Chris) Scharer
Keywords(s): Cell Line, Immunology/Inflammation
Category(s): TechPub Algolia > Research Tools
Recombinant Respiratory Syncytial Virus (RSV) Firefly Luciferase Reporter Strain
Application Modified recombinant syncytial virus (RSV) strain expressing a bioluminescent reporter protein for high throughput screening and vaccine development. Key Benefits Provides a new high throughput screening tool for RSV vaccine development and drug discovery. Firefly luciferase based assays show better signal-to-noise than fluorescence-based...
Published: 9/26/2024   |   Inventor(s): Richard Plemper, Martin Moore
Keywords(s): Immunology/Inflammation, Microbiology/Infectious Diseases, Respiratory
Category(s): TechPub Algolia > Research Tools, TechPub Algolia > Vaccines
Recombinant RSV Strains Expressing Renilla Luciferase and G & F Proteins
Application Recombinant respiratory syncytial virus (RSV) strains expressing the G and F Proteins from RSV strains as well as renilla luciferase for use in drug and vaccine screening. Key Benefits Provides new and needed tool for screening potential RSV therapies, ensuring they are broadly effective against multiple, distinct strains of the virus....
Published: 9/26/2024   |   Inventor(s): Martin Moore, Jia Meng
Keywords(s): Immunology/Inflammation, Microbiology/Infectious Diseases, Respiratory
Category(s): TechPub Algolia > Research Tools, TechPub Algolia > Vaccines
Respiratory Syncytial Virus (RSV) A/2001/2-20 Strain with Enhanced Pathogenesis
Applications Strain of respiratory syncytial virus (RSV) for use in drug and vaccine development. Key Benefits Exhibits increased mucin expression and early epithelial damage in mouse models. Provides a platform for animal models focused on early airway histopathology. Market Summary RSV is the most common cause of severe respiratory illness...
Published: 9/26/2024   |   Inventor(s): Martin Moore
Keywords(s): Immunology/Inflammation, Microbiology/Infectious Diseases, Respiratory
Category(s): TechPub Algolia > Research Tools, TechPub Algolia > Vaccines
Triptolide Analog as Potent Anti-Inflammatory Drug Candidate
Application Small molecule therapeutics for the treatment of inflammation and autoimmune disorders. Key Benefits Decreased toxicity compared to the natural product triptolide. Improved aqueous solubility compared to triptolide. Market Summary Inflammation is known to be a component in a wide range of disease states including arthritis, asthma,...
Published: 9/26/2024   |   Inventor(s): Hariharan Venkatesan, James Snyder, Dennis Liotta, Susheng Wang
Keywords(s): Immunology/Inflammation, Small Molecule
Category(s): TechPub Algolia > Therapeutics