Search Results - pradeep+kumar

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JSF-3285, A Novel KasA Inhibitor for Tuberculosis
Figure 1. Summary profile of JSF-3285: A) In vitro profile. B) X-ray crystal structure and binding constant for complex with KasA. C) In vivo profile in mouse chronic infection model. Invention Summary: New antibacterial drugs that treat multidrug resistant mycobacterium tuberculosis (MDR TB) represent an area of high medical need. The current tuberculosis...
Published: 7/26/2024   |   Inventor(s): Joel Freundlich, David Alland, Matthew Neiditch, Glenn Capodagli, Sean Ekins, Pradeep Kumar, Divya Awasthi, Daigo Inoyama
Keywords(s): Antibacterial
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics
Therapeutic Target for Hepatic Fibrosis
ApplicationPeriostin as a therapeutic target for liver disease.Key BenefitsNew therapeutic target for preventing fibrosis from entering cirrhosis stage.Therapeutic target may be used for identifying new therapy for fibrosis.Market SummaryCirrhosis is a condition in which the liver is unable to function normally due to chronic, or long lasting, injury....
Published: 7/30/2024   |   Inventor(s): Frank Anania, Pradeep Kumar
Keywords(s): Enzyme/Protein, Hepatology, Immunology/Inflammation, Target
Category(s): TechPub Algolia > Therapeutics, TechPub Algolia > Drug Discovery