Search Results - yanshu+shi

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Ultrasound-programmable nanoparticles for targeted drug release
Background/problem Ideally, a drug meant to accurately target specific tissues or cells involved in a disease will do so and achieve an optimal dose and treatment duration. These will yield the intended cellular and physiological response without undue off-target and side effects. And yet, we live with the reality and risks of side effects. Novel...
Published: 5/6/2025   |   Inventor(s): Wenliang Wang, Huiliang Wang, Yanshu Shi, Banglin Chen
Keywords(s):  
Category(s): Life sciences > Therapeutics > Drug delivery, Life sciences > Biomaterials
Helical Sulfono-γ-AApeptide Antagonize β-Catenin Signaling
Competitive Advantages Potent, specific, and cell permeable to target intracellular PPIs High stability against enzymatic degradation More effective than other peptides at antagonizing Wnt/β-catenin signaling Summary Protein-protein interactions (PPIs) are vital to the survival of cancer cells and are therefore a good target for anti-cancer...
Published: 7/17/2023   |   Inventor(s): Jianfeng Cai, Peng Sang, Yan Shi, Haitao Ji, Min Zhang
Keywords(s): Cancer, Cancer Treatment Leukemias, Cancer Treatment Lymphomas, Peptides, Therapeutics
Category(s): Technology Classifications > Cancer