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Novel Helical Peptodomimetics that Prevent the Formation of Aβ Oligomerization in Alzheimer’s Disease (AD)

Advantages: Developed sulfonyl-γ-AA peptide helical peptidomimetics that can prevent the formation of neurotoxic Aβ oligomerization. High Specificity: The lead sulfonyl-γ-AApeptide helical foldamer, Ab-6, exhibits precise targeting to the central region of Aβ42 and induces α-helix conformation in Aβ. Sequence-Specific...

Published: 9/12/2024 | Inventor(s): Jianfeng Cai, Heng Liu

Keywords(s): Alzheimer's Disease, Biotechnology, Neurodegenerative Diseases

Category(s): Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Medical > Biotechnology, Technology Classifications > Medical > Neuroscience

Microbial Electrosynthesis of Single Cell Protein

This technology uses a microbial electrolysis cell to consume organic waste and produce high quality single cell protein Background As population growth continues, the world is increasingly deficient in high quality protein. Most protein is produced from an inefficient industrial agriculture system that depletes natural resources and stresses arable...

Published: 5/30/2024 | Inventor(s): Hong Liu, Luguang Wang, Kevin Linowski

Keywords(s): animal feed, microbial electrolysis cell, single cell protein

Category(s): Biological Materials, Chemistry

DNA Methylation Barriers

In normal differentiated cells, most of the genome is densely methylated, except CpG islands near promoters of actively transcribed genes. Maintaining this boundary between unmethylated promoter-associated and adjacent methylated regions is crucial as loss of segregation can lead to disease. Unfortunately, it is not clear where these boundaries are,...

Published: 6/5/2024 | Inventor(s): Li Liu, Jingmin Shu

Keywords(s):

Category(s): Applied Technologies, Genomic Assays/Reagents/Tools, Life Science (All LS Techs), Diagnostic Assays/Devices

ONE GRAM PENNY-SIZED WIRELESS EEG RECORDING PATCH FOR LONG-TERM MENTAL HEALTH MONITORING

ONE GRAM PENNY-SIZED WIRELESS EEG RECORDING PATCH FOR LONG-TERM MENTAL HEALTH MONITORING Researchers at Stanford have developed a wearable patch that allows for continuous mental health monitoring via electroencephalogram (EEG) recording. EEG technology was developed during the advent of neuroscience nearly a century and a half ago. EEG technology...

Published: 8/17/2023 | Inventor(s): Ada Poon, Cheng Chen, Joonseok Yang, Hui Wang

Keywords(s): EEG, Neurology, Wearable

Category(s): Technology Classifications > Engineering

Thermal Drift Calibration of Whispering Gallery Mode Microcavities using Optical Frequency Domain Reflectometry

This technology utilizes optical frequency domain reflectometry (OFDR) to collect high resolution temperature measurements in biochemical applications. More specifically, accuracy of measurements is increased in the spatial domain via the OFDR technology being studied in conjunction with whispering gallery mode biochemical sensing. While temperature...

Published: 6/6/2024 | Inventor(s): Tsu-Te Su, Cheng Li

Keywords(s):

Category(s): Technology Classifications, Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Telecommunications > Electro-Optic Devices

Novel Multi-Omics Aging Clock

A multi-omics clock analyzes multiple layers of omics data with machine learning to predict remaining lifespan of mammals, particularly for animal model studies. Large omics data sets may be used from combinations of genomics, proteomics, lipids, etc. available from blood or other simple sample collection. This tool can robustly capture changes...

Published: 3/12/2024 | Inventor(s): George Sutphin, Samuel Freitas, Megha Padi, Chen Chen

Keywords(s):

Category(s): Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools > Screening assays, Technology Classifications > Research Tools > Simulators and Modeling Tools

Autonomous Drone for railroad track inspection

Reference #: 01564 The University of South Carolina is offering licensing opportunities for Autonomous Drone for railroad track inspection Background: The current practices suffer from three main drawbacks: 1) Human pilot cost is significant. The schedule of the drone-based track inspection is contingent on the pilot’s availability rather than...

Published: 3/15/2023 | Inventor(s): Yu Qian, Yi Wang, Chen Chen

Keywords(s): autonomous drone, flight control, image processing, railroad track inspection, self-navigation

Category(s): Engineering and Physical Sciences

Scalable two-phase cooling plates

Reference #: 01575 The University of South Carolina is offering licensing opportunities for Scalable two-phase cooling plates Background: Two-phase cooling usually fails at relatively low heat loads due to the loss of liquid supply. For real applications, two-phase cooling technologies need to match the size of electronic components. However, the...

Published: 11/7/2022 | Inventor(s): Chen Li, Wei Chang, Enrico Santi, Bo Tian

Keywords(s): cold plate, high power device, Thermal management, Two-phase cooling

Category(s): Engineering and Physical Sciences, Software and Computing

PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids

The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...

Published: 7/30/2024 | Inventor(s): Payman Dehghanian, Shiyuan Wang, Li Li

Keywords(s):

Category(s): Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment

JobViz: User Interface for Visualization of Majors & Jobs

Invention Summary: University (and industry) career search portals and web-based job search engines allow users to search on many items (e.g., education, location, level, etc.) and then present a text based list of potential job opportunities. University career portals are not as conductive to exploration by job and career searchers as they could...

Published: 9/8/2022 | Inventor(s): Deborah Silver, Li Liu

Keywords(s):

Category(s): Technology Classifications > Software & Copyright, Technology Classifications > Software & Algorithms

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