Search Results - guokai+chen

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Improved Culture Medium for Stem Cell Maintenance and Differentiation

A novel low protein culture medium with defined chemical components that allows pluripotent stem cell maintenance and differentiation is disclosed. The present technology also provides for production of high quality cardiac cells from human embryonic and induced pluripotent stem cells in chemically defined medium conditions. Human pluripotent stem...

Published: 10/28/2024 | Inventor(s): Yongshun Lin, Guokai Chen

Keywords(s): AC5XXX, ACXXXX, ADDITIVES, AXXXXX, Cell, Chemically, CM-dextran, CULTURE, DEFINED, DIFFERENTIATION, GLYCOGEN, HEPARIN, Human, IMPROVING, Lipid, Maintenance, Medium, Pluripotent, RXXXXX, Stem, Trehalose

Category(s): Collaboration Sought > Collaboration, Application > Research Materials

Novel Multi-Omics Aging Clock

A multi-omics clock analyzes multiple layers of omics data with machine learning to predict remaining lifespan of mammals, particularly for animal model studies. Large omics data sets may be used from combinations of genomics, proteomics, lipids, etc. available from blood or other simple sample collection. This tool can robustly capture changes...

Published: 3/12/2024 | Inventor(s): George Sutphin, Samuel Freitas, Megha Padi, Chen Chen

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Category(s): Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools > Screening assays, Technology Classifications > Research Tools > Simulators and Modeling Tools

Autonomous Drone for railroad track inspection

Reference #: 01564 The University of South Carolina is offering licensing opportunities for Autonomous Drone for railroad track inspection Background: The current practices suffer from three main drawbacks: 1) Human pilot cost is significant. The schedule of the drone-based track inspection is contingent on the pilot’s availability rather than...

Published: 3/15/2023 | Inventor(s): Yu Qian, Yi Wang, Chen Chen

Keywords(s): autonomous drone, flight control, image processing, railroad track inspection, self-navigation

Category(s): Engineering and Physical Sciences

2015-671 Underground Shafts for Hydrogen Storage

SummaryResearchers at UCLA have developed an underground drilled shaft concept for storage of hydrogen or other gases.BackgroundOne challenge in creating a hydrogen economy is developing hydrogen gas storage solutions. Increased interest has helped the global hydrogen storage market grow to $2.6 billion in 2016, and it is expected to reach over $5...

Published: 7/19/2023 | Inventor(s): Adrienne Lavine, Hossein Kavehpour, Dante Simonetti, Richard Wirz, Chen Chen, Gabriela Bran, Gopinath Warrier, Hamarz Aryafar, Jonathon Kennedy, Joshua Jordan, Keith Lovegrove

Keywords(s): Energy & Water

Category(s): Energy & Environment > Energy Generation > Solar, Energy & Environment > Energy Storage

2013-428 Methods of Diagnosing Ocular Diseases

SUMMARYResearchers at UCLA have developed a novel technique to detect ocular diseases.BACKGROUNDThe ophthalmic device market is expected to grow to $58.44 billion by 2023. Diseases of the eye often stem from perturbations in the homeostatic rate of cell turnover, and the process by which cell death occurs may affect cellular response of surrounding...

Published: 7/19/2023 | Inventor(s): Jacky M.K. Kwong, Chris Koon Pak, Brain Gray, Richard Yee, Kai Chen

Keywords(s): Diagnostic Markers & Platforms, Fluorescence, Life Science Research Tools, Medical Imaging, Microscopy And Imaging, Ophthalmology

Category(s): Life Science Research Tools, Life Science Research Tools > Microscopy And Imaging, Diagnostic Markers, Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > Fluorescence, Therapeutics > Ophthalmology

Small Molecule Inhibitors of Mcl-1 as Anti-Cancer Agent

Application Myeloid cell leukemia 1 (Mcl-1) inhibitor to enhance DNA replication stress sensitivity for cancer therapy. Key Benefits Inhibits DNA repair in cancer cells. Used in combination with existing cancer therapy. Market Summary Chemoresistance occurs when cancer cells develop resistance to chemotherapy drugs, and appearance of chemoresistance...

Published: 10/28/2024 | Inventor(s): Xingming Deng, Guo Chen, Abu Syed Md Anisuzzaman

Keywords(s): Oncology, Small Molecule

Category(s): TechPub Algolia > Therapeutics, TechPub Algolia > Drug Discovery

New Quantitative Method to Apply Tagmentation Technology to ChIP-Seq

Princeton Docket # 16-3268Chromatin immunoprecipitation (ChIP) is an affinity assay for detecting the interaction between a particular protein and DNA in cells. Using a protein-specific antibody, DNA bound by that protein can be isolated and identified using high throughput sequencing (ChIP-seq). One desirable way to prepare a DNA library for sequencing...

Published: 3/30/2022 | Inventor(s): Michael Levine, Kai Chen

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Category(s): Biotechnology/Pharmaceuticals