2013-428 Methods of Diagnosing Ocular Diseases

SUMMARY

Researchers at UCLA have developed a novel technique to detect ocular diseases.

BACKGROUND

The ophthalmic device market is expected to grow to $58.44 billion by 2023. Diseases of the eye often stem from perturbations in the homeostatic rate of cell turnover, and the process by which cell death occurs may affect cellular response of surrounding cells and induce premature incidence. Current diagnostic practices for these diseases are limited to relying on patient response and technologies with low sensitivity. These detection constraints delay diagnosis and prevent accurate tracking of disease progression.

INNOVATION

Kwong and colleagues have developed an innovative method to diagnose and chart the progression of ocular diseases by live, in vivo imaging. Molecular factors involved in cell death are labeled locally and monitored using state-of-the-art non-invasive imaging techniques. The improved tracking ability enables closer monitoring of response to therapy and increased understanding of disease towards improved therapeutics.

APPLICATIONS

  • Tracking of ocular diseases progression – Glaucoma, Neuropathies
  • Early diagnosis of ocular diseases

 

ADVANTAGES

  • Live, in vivo monitoring
  • Local or topical administration

STATE OF DEVELOPMENT

This technique has been validated in experimental models.

Patent Information: