Search Results - guangyu+xu

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Production of cyclopeptibodies with high target affinity and specificity that can be used as a replacement for antibodies
Background Antibodies find widespread use as therapeutic agents and for diagnostic, imaging, and immunodetection applications. Major limitations of antibodies, however, are their complex structure, limited stability, poor tissue penetration, complex manufacturing process, and associated high costs of production. Despite their numerous and important...
Published: 5/7/2024   |   Inventor(s): Rudi Fasan, Yu Gu
Keywords(s):  
Category(s): Therapeutic
Miniaturized, Cost-Effective Biosensing Devices for Point-of-Care and Therapeutic Screening Applications
PRODUCT OPPORTUNITIES• Miniaturized point-of-care (POC) cytokine sensing devices• Miniaturized point-of-care (POC) devices for rapid and real-time detection of biomarkers• Spectrally-filtered photodiode pairs for ratiometric sensing of biomolecules• Miniaturized biosensing devices for therapeutic screening...
Published: 8/3/2023   |   Inventor(s): Guangyu Xu
Keywords(s):  
Category(s): Biotechnology, Devices, Devices & sensors, Diagnostic technology, Healthcare, Life Sciences, Engineering, Research tools
Novel Selective Activators of Neuronal GIRK Heteromeric Channels Effective in Animal Models of Post-Traumatic Stress Disorder
-collapse: collapse; } INV-18111 Background G protein-gated inwardly rectifying potassium (GIRK) channels, are channels distributed throughout the central nervous system as well as the heart. Pharmacological investigations of GIRK channels, along with studies in animal models, suggest that GIRK activity has an important role in physiological...
Published: 11/25/2024   |   Inventor(s): Ganeshsingh Thakur, Diomedes Logothetis, Anantha Shekhar, Yu Xu, Lucas Cantwell
Keywords(s):  
Category(s): Technology Classifications > 1. Life Science > Therapeutics
Chance-Constrained Optimization for Treatment of Prostate and Other Cancers in Intensity-Modulated Proton Therapy
The quality of IMPT treatment plans may be drastically diminished by uncertainties such as proton range and patient setup errors. If these uncertainties are not figured into treatment planning, the dose distribution that the patient receives may not be the same as the planned dose distribution. New treatment plans, which include optimized software/programming,...
Published: 12/18/2024   |   Inventor(s): Jianming Liang, Yu An, Wei Liu
Keywords(s):  
Category(s): Computing & Information Technology, Life Science (All LS Techs), Medical Imaging