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Prototype Software for Neuron-Centric Memory Architecture in AI (Case Nos. 2025-327/328)
Summary: Researchers at UCLA’s Department of Integrative Biology & Physiology and Neurobiology have pioneered the first prototype of a novel, neuron-centric AI architecture featuring intracellular memory and adaptive computation capabilities, designed to enhance deep learning performance and efficiency. Background: Deep learning leverages...
Published: 10/24/2025   |   Inventor(s): Alain Glanzman, David Glanzman
Keywords(s): Artifical Intelligence (Machine Learning, Data Mining), Artificial Intelligence, artificial intelligence algorithms, artificial intelligence augmentation, artificial intelligence/machine learning models, artificial intelligence-generated content, Artificial Neural Network, Artificial Neural Network Artificial Neuron, artificial-intelligent materials, generative artificial intelligence, Medical artificial intelligence (AI), Neuron, neurons, Software, Software & Algorithms, Software Development Tools, Software-enabled learning
Category(s): Software & Algorithms, Software & Algorithms > AI Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Electrical, Electrical > Computing Hardware
DELIVERY OF CRISPR COMPONENTS
Researchers at UC Berkeley have developed novel strategies for the delivery of CRISPR gene editing components. While CRISPR-based gene editing holds great promise for treating genetic diseases, it often involves DNA breaks or base changes that can cause off-target effects, cell damage, or unpredictable outcomes. Additionally, these changes are often...
Published: 10/23/2025   |   Inventor(s): James Nunez, Da Xu, Swen Besselink
Keywords(s): CRISPR, Epigenetics
Category(s): Technology Classifications > Biology
ANTIBODY DIRECTED THERAPY TO PREVENT AND TREAT CHRONIC LUNG DISEASE OF INFANCY
Researchers at Stanford and CZ Biohub SF have developed a novel antibody mediated strategy for the treatment of pediatric chronic lung diseases. Over 10% of infants worldwide are born prematurely, many of whom develop bronchopulmonary dysplasia (BPD), a serious lung disease with many comorbities. In the U.S., around 10,000 infants are diagnosed with...
Published: 10/23/2025   |   Inventor(s): David Cornfield, Cristina Alvira, Stephen Quake, Carsten Knutsen
Keywords(s): Antibody, Therapeutic
Category(s): Technology Classifications > Biology
METHODS, COMPOSITIONS, AND SYSTEMS TO DETECT NON-SMALL CELL LUNG CANCER
Researchers at CZ Biohub SF and UCSF have developed novel methods for the early detection of non-small cell lung cancer. Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related deaths in the U.S., with many cases diagnosed at an advanced stage, significantly reducing survival rates. Although low-dose chest CT (LDCT) scans are effective...
Published: 10/23/2025   |   Inventor(s): Chukwuka Didigu, Joseph DeRisi, David Jablons, Johannes Kratz, Andrew Kung
Keywords(s): Cancer, Diagnosis
Category(s): Technology Classifications > Biology
A Precision Anti-Infective for Enterococcus sp Eradication as well as Selective Decontamination
This innovation is a water-soluble nanocarrier that can precisely and quickly eradicate the healthcare-associated pathogen enterococci. The carrier can complex with oligonucleotides that can bind to bacterial mRNA, preventing translation and inhibiting bacterial functions of enterococci. It is also non-toxic to both human tissue and bacteria and may...
Published: 10/20/2025   |   Inventor(s): Gayatri Vedantam, Virinchipuram Viswanathan, Arun Sharma, David Stewart
Keywords(s):  
Category(s): Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Infectious Diseases
One-pot assembly of long, modified DNA via scaffolded oligo ligation
Background As synthetic biology advances, the need for efficient construction of long, chemically modified DNA has become increasingly critical across applications such as gene editing, DNA data storage, epigenetics, and personalized therapeutics. These technologies require precise, site-specific incorporation of chemical tags into DNA strands that...
Published: 10/1/2025   |   Inventor(s): David Soloveichik, David Doty, Nadia Alvarado
Keywords(s):  
Category(s): Life sciences > Research tools > Tool/assay/screening platform
One-pot assembly of long, modified DNA via scaffolded oligo ligation
Background As synthetic biology advances, the need for efficient construction of long, chemically modified DNA has become increasingly critical across applications such as gene editing, DNA data storage, epigenetics, and personalized therapeutics. These technologies require precise, site-specific incorporation of chemical tags into DNA strands that...
Published: 10/1/2025   |   Inventor(s): David Soloveichik, David Doty, Nadia Alvarado
Keywords(s):  
Category(s): Life sciences > Research tools > Tool/assay/screening platform
Polyaniline-based Coatings for Electronic Applications
Invention Description Polyaniline (PANI) is a conductive polymer with excellent electrical conductivity lending it great utility in numerous electronics applications including electronic devices, sensors, batteries and more. While PANI can be easily deposited on many surfaces, it has difficulty with producing a dense coating on insulating substrates,...
Published: 9/30/2025   |   Inventor(s): Dong-Kyun Seo, David Ciota
Keywords(s):  
Category(s): Advanced Materials/Nanotechnology, Applied Technologies, Chemical/Biological Sensors, Physical Science, Manufacturing/Construction/Mechanical
Microfluidic Device Design for Point-of-Care Devices
Implementing liquid-based assays, such as PCR and LAMP, is difficult in POC microfluidic devices, due to bubble formation. To mitigate this, auxiliary metering systems or actuators are required to regulate consistent flow rates. This can make the microfluidic device more complicated to operate, increases cost, and limits rapid prototyping, ultimately...
Published: 9/29/2025   |   Inventor(s): Vi Nguyen, Jennifer Blain Christen
Keywords(s):  
Category(s): Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Manufacturing/Construction/Mechanical, Medical Diagnostics/Sensors, Genomic Assays/Reagents/Tools
Interferometric Focal Planes
This technology introduces a new kind of camera sensor in which each pixel functions as a tiny interferometer, instead of a standard light detector. This allows the sensor to capture not only the brightness of a scene but also additional information about the light’s spatial coherence. By leveraging arrays of integrated interferometers, the system...
Published: 9/29/2025   |   Inventor(s): David Brady, Shengtai Zhu, Zhipeng Dong
Keywords(s):  
Category(s): Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry, Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Imaging & Optics > Lens & System Design
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