Search Results - chronic+pain

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A new CNS-available formulation HDACi for management of chronic pain
A new CNS-available formulation HDACi for management of chronic pain NU 2017-031 INVENTORS Vania A. Apkarian* Kasturi Haldar Maria V. Centeno Suhail Alam SHORT DESCRIPTION A novel non-opioid, epigenetic drug for pain relief BACKGROUND Chronic pain is a major public health problem, and it is the number one source of disability in the...
Published: 7/3/2024   |   Inventor(s):  
Keywords(s): Biomedical, Chronic pain, Neurologic disease, Small molecule, Therapeutics
Category(s): Life Sciences > Therapeutics
Escherichia coli From Human Prostate
NU 2010-012 Inventors Praveen Thumbikat Anthony Schaeffer* Short Description Novel bacterial strain for research of chronic pelvic painAbstract Northwestern researchers have discovered uropathogenic Escherichia coli (UPEC) that causes chronic prostatitis/chronic pelvic pain (CP/CPP). Despite an urgent need for a greater understanding of this disease,...
Published: 7/3/2024   |   Inventor(s):  
Keywords(s): Cell therapy, Chronic pain, Research tool, Therapeutics, Urology
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
AMPA Receptor Agonists for Neurologic Diseases
NU 2009-186 Inventors Geoffrey Swanson* Martin Gill Ryuichi Sakai Masato Oikawa Short Description Novel class of compounds that selectively targets AMPA receptors in the brain for treatment of epilepsy and pain Abstract Northwestern scientists have discovered that a new class of compounds, named IKM, binds to AMPA receptors in the brain. This...
Published: 7/3/2024   |   Inventor(s):  
Keywords(s): Chronic pain, Neurologic disease, Small molecule, Therapeutics
Category(s): Life Sciences > Therapeutics
Microbial Modulation of Immunity and Pain
NU 2008-022 Inventors David Klumpp* Anthony Schaeffer* Praveen Thumbikat Short DescriptionAn attenuated-live UTI vaccineAbstract Northwestern researchers have developed therapies to treat urinary tract infection (UTI). They use novel UTI therapeutic approaches by targeting the cell-mediated response instead of the humoral responses, which is the...
Published: 7/3/2024   |   Inventor(s):  
Keywords(s): Biomarker, Chronic pain, Therapeutics, Vaccine
Category(s): Life Sciences > Therapeutics
Small Molecule for Treatment of Epilepsy, Pain, and Other Neurological Disorders
NU 2007-036 InventorsLeanne Lash Geoffrey Swanson* Ryuichi Sakai AbstractOver-activation of AMPA receptors contributes to the pathology of a number of neurological diseases, particularly epilepsy, neuropathic pain, and stroke. A new group of heterotricyclic molecules called 'IKM' analogs have been determined to act pharmacologically as AMPA receptor...
Published: 7/3/2024   |   Inventor(s):  
Keywords(s): Chronic pain, Small molecule, Therapeutics
Category(s): Life Sciences > Therapeutics