Search Results - aldons+lusis

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y-AApeptide-based long-acting pan-coronavirus fusion inhibitor with dual targets in spike protein and oral bioavailability
­Advantages: S-20-1 demonstrates potent inhibitory action, this broad-spectrum activity suggests that S-20-1 could be effective against a wide range of coronaviruses, making it a valuable candidate for pandemic preparedness and management. The research provides insights into the mechanism of action of S-20-1, demonstrating its ability to bind...
Published: 9/25/2023   |   Inventor(s): Jianfeng Cai, Shibo JIANG, Lu LU, Songyi XUE, Xinling WANG, Lei WANG, Wei XU, Shuai XIA
Keywords(s): Drug Discovery, Immunology
Category(s): Technology Classifications > Medical > Biotechnology
2020-404 IDENTIFICATION OF NOVEL BIOMARKERS FOR NON-ALCOHOLIC FATTY LIVER DISEASE
SUMMARY: UCLA Researchers in the department of medicine have discovered distinct protein signatures in the blood of patients with non-alcoholic fatty liver disease (NAFLD) as well as NAFLD-related traits including steatosis, hepatocellular ballooning, and non-alcoholic steatohepatitis (NASH). These proteins were identified using the next-generation...
Published: 9/5/2023   |   Inventor(s): Adriana Huertas Vazquez, Aldons Lusis
Keywords(s):  
Category(s): Diagnostic Markers > Targets And Assays, Therapeutics > Metabolism And Endocrinology
2016-876 DEVELOPMENT OF A METHOD FOR ENDOCRINE NETWORK DISCOVERY UNCOVERS PEPTIDE THERAPEUTIC TARGETS
Development Of A Method For Endocrine Network Discovery Uncovers Peptide Therapeutic TargetsSUMMARYUCLA researchers in the Division of Cardiology at the Geffen School of Medicine have developed a bioinformatics methodology to identify and functionally annotate novel endocrine pathways.BACKGROUNDBeginning with the discovery of insulin, endocrine tissue...
Published: 8/2/2024   |   Inventor(s): Aldons Lusis, Marcus Seldin
Keywords(s): Life Science Research Tools, Software
Category(s): Life Science Research Tools, Software & Algorithms > Programs
2014-730 AGPAT5 as a Molecular Mediator of Insulin Resistance
AGPAT5 as a Molecular Mediator of Insulin ResistanceSUMMARYUCLA researchers in the Departments of Medicine and Cardiology have identified a novel gene and pathway in the regulation of insulin sensitivity and discovered an inhibitor of this gene useful for treating AGPAT5-related diseases.BACKGROUNDInsulin resistance (IR), a condition in which the body’s...
Published: 7/19/2023   |   Inventor(s): Aldons Lusis, Brian Parks, Richard Lee
Keywords(s): Cardiovascular, Diagnostic Markers & Platforms, Metabolic Diseases, Therapeutics & Vaccines
Category(s): Diagnostic Markers, Therapeutics, Therapeutics > Cardiovascular, Therapeutics > Metabolism And Endocrinology
2017-503 USING DNA METHYLATION MARKERS TO PREDICT CLINICALLY IMPORTANT TRAITS IN MAMMALS
Using DNA Methylation Markers To Predict Clinically Important Traits In MammalsSUMMARYUCLA researchers in the Department of Molecular, Cell, and Developmental Biology have found association of DNA methylation with metabolic syndrome traits in human adipose tissue samples using epigenome-wide association studies (EWAS).BACKGROUNDThe genome-wide association...
Published: 7/19/2023   |   Inventor(s): Steve Jacobsen, Matteo Pellegrini, Aldons Lusis
Keywords(s): Life Science Research Tools, Research Methods
Category(s): Life Science Research Tools, Life Science Research Tools > Research Methods
Network-Coded Multiple Access
[Licensing negotiation in progress] [Invitation for Expression of Interest - Deadline: 16 June 2016] Systems and methods include a first wireless local area network (WLAN) system that jointly exploit physical-layer network coding (PNC) and multi-user decoding (MUD) to boost system throughput. This multiple access mode is referred to as Network-Coded...
Published: 1/29/2024   |   Inventor(s): Soung Chang Liew, Lu LU, Lizhao You
Keywords(s): Network Coding, Wireless Local Area Network
Category(s): Information and Communications Technology