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Search Results - aldons+lusis
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y-AApeptide-based long-acting pan-coronavirus fusion inhibitor with dual targets in spike protein and oral bioavailability
Advantages: S-20-1 demonstrates potent inhibitory action, this broad-spectrum activity suggests that S-20-1 could be effective against a wide range of coronaviruses, making it a valuable candidate for pandemic preparedness and management. The research provides insights into the mechanism of action of S-20-1, demonstrating its ability to bind...
Published: 9/25/2023
|
Inventor(s):
Jianfeng Cai
,
Shibo JIANG
,
Lu LU
,
Songyi XUE
,
Xinling WANG
,
Lei WANG
,
Wei XU
,
Shuai XIA
Keywords(s):
Drug Discovery
,
Immunology
Category(s):
Technology Classifications > Medical > Biotechnology
2020-404 IDENTIFICATION OF NOVEL BIOMARKERS FOR NON-ALCOHOLIC FATTY LIVER DISEASE
SUMMARY: UCLA Researchers in the department of medicine have discovered distinct protein signatures in the blood of patients with non-alcoholic fatty liver disease (NAFLD) as well as NAFLD-related traits including steatosis, hepatocellular ballooning, and non-alcoholic steatohepatitis (NASH). These proteins were identified using the next-generation...
Published: 9/5/2023
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Inventor(s):
Adriana Huertas Vazquez
,
Aldons Lusis
Keywords(s):
Category(s):
Diagnostic Markers > Targets And Assays
,
Therapeutics > Metabolism And Endocrinology
2016-876 DEVELOPMENT OF A METHOD FOR ENDOCRINE NETWORK DISCOVERY UNCOVERS PEPTIDE THERAPEUTIC TARGETS
Development Of A Method For Endocrine Network Discovery Uncovers Peptide Therapeutic TargetsSUMMARYUCLA researchers in the Division of Cardiology at the Geffen School of Medicine have developed a bioinformatics methodology to identify and functionally annotate novel endocrine pathways.BACKGROUNDBeginning with the discovery of insulin, endocrine tissue...
Published: 8/2/2024
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Inventor(s):
Aldons Lusis
,
Marcus Seldin
Keywords(s):
Life Science Research Tools
,
Software
Category(s):
Life Science Research Tools
,
Software & Algorithms > Programs
2014-730 AGPAT5 as a Molecular Mediator of Insulin Resistance
AGPAT5 as a Molecular Mediator of Insulin ResistanceSUMMARYUCLA researchers in the Departments of Medicine and Cardiology have identified a novel gene and pathway in the regulation of insulin sensitivity and discovered an inhibitor of this gene useful for treating AGPAT5-related diseases.BACKGROUNDInsulin resistance (IR), a condition in which the body’s...
Published: 7/19/2023
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Inventor(s):
Aldons Lusis
,
Brian Parks
,
Richard Lee
Keywords(s):
Cardiovascular
,
Diagnostic Markers & Platforms
,
Metabolic Diseases
,
Therapeutics & Vaccines
Category(s):
Diagnostic Markers
,
Therapeutics
,
Therapeutics > Cardiovascular
,
Therapeutics > Metabolism And Endocrinology
Network-Coded Multiple Access
[Licensing negotiation in progress] [Invitation for Expression of Interest - Deadline: 16 June 2016] Systems and methods include a first wireless local area network (WLAN) system that jointly exploit physical-layer network coding (PNC) and multi-user decoding (MUD) to boost system throughput. This multiple access mode is referred to as Network-Coded...
Published: 1/29/2024
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Inventor(s):
Soung Chang Liew
,
Lu LU
,
Lizhao You
Keywords(s):
Network Coding
,
Wireless Local Area Network
Category(s):
Information and Communications Technology