Search Results - aldons+lusis

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Indole-3-Propionic Acid (IPA) Protects Against Heart Failure with Preserved Ejection Fraction (HFpEF) (UCLA Case No. 2022-142)
UCLA researchers in Department of Medicine, Division of Cardiology have identified the protective effects of gut-heart crosstalk mediated by 3-propionic acid (IPA) in the progression of heart failure with preserved ejection fraction (HFpEF). IPA supplementation could rescue the IPA deficiency associated heart defects, protect against heart malfunction,...
Published: 2/5/2026   |   Inventor(s): Aldons Lusis, Yang Cao
Keywords(s):  
Category(s): Therapeutics > Cardiovascular
Coagulation Factor XI (FXI) Functional Roles and Regulation for Treatment of Heart Failure (UCLA Case No. 2022-141)
UCLA researchers from the Department of Medicine have discovered a novel therapeutic target (between the interaction of the heart and liver) to treat heart failure with preserved ejection fraction (HFpEF), which afflicts approximately half of all patients with heart failure. Contact UCLA Technology Development Group for more information. Related papers...
Published: 2/5/2026   |   Inventor(s): Aldons Lusis
Keywords(s):  
Category(s): Therapeutics > Cardiovascular, Therapeutics > Metabolism And Endocrinology
2016-876 DEVELOPMENT OF A METHOD FOR ENDOCRINE NETWORK DISCOVERY UNCOVERS PEPTIDE THERAPEUTIC TARGETS
Development Of A Method For Endocrine Network Discovery Uncovers Peptide Therapeutic TargetsSUMMARYUCLA researchers in the Division of Cardiology at the Geffen School of Medicine have developed a bioinformatics methodology to identify and functionally annotate novel endocrine pathways.BACKGROUNDBeginning with the discovery of insulin, endocrine tissue...
Published: 2/14/2025   |   Inventor(s): Aldons Lusis, Marcus Seldin
Keywords(s): Life Science Research Tools, Software
Category(s): Life Science Research Tools, Software & Algorithms > Programs
2014-730 AGPAT5 as a Molecular Mediator of Insulin Resistance
AGPAT5 as a Molecular Mediator of Insulin ResistanceSUMMARYUCLA researchers in the Departments of Medicine and Cardiology have identified a novel gene and pathway in the regulation of insulin sensitivity and discovered an inhibitor of this gene useful for treating AGPAT5-related diseases.BACKGROUNDInsulin resistance (IR), a condition in which the body’s...
Published: 7/17/2025   |   Inventor(s): Aldons Lusis, Brian Parks, Richard Lee
Keywords(s): Cardiovascular, Diagnostic Markers & Platforms, Metabolic Diseases, Therapeutics & Vaccines
Category(s): Diagnostic Markers, Therapeutics, Therapeutics > Cardiovascular, Therapeutics > Metabolism And Endocrinology
Network-Coded Multiple Access
[Licensing negotiation in progress] [Invitation for Expression of Interest - Deadline: 16 June 2016] Systems and methods include a first wireless local area network (WLAN) system that jointly exploit physical-layer network coding (PNC) and multi-user decoding (MUD) to boost system throughput. This multiple access mode is referred to as Network-Coded...
Published: 1/29/2024   |   Inventor(s): Soung Chang Liew, Lu LU, Lizhao You
Keywords(s): Network Coding, Wireless Local Area Network
Category(s): Information and Communications Technology