Search Results - scrna-seq

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PROBE-BASED DEVICE-FREE SINGLE-CELL RNA PROFILING

PROBE-BASED DEVICE-FREE SINGLE-CELL RNA PROFILING Researchers at UCSF have developed a novel method for probe-based scRNA-seq. Single cell RNA sequencing (scRNA-seq) has revolutionized the field of cell biology by enabling nucleic acid profiling at single cell resolution. Typical detection efficiency of scRNA-seq ranges between 5-45%, mostly...

Published: 12/5/2023 | Inventor(s): Bo Huang, Daniel Foyt

Keywords(s): Barcoding, RNA Sequencing, ScRNA-seq

Category(s): Technology Classifications > Biology

PARTICLE-TEMPLATED EMULSIFICATION IN WELL PLATES

PARTICLE-TEMPLATED EMULSIFICATION IN WELL PLATES Researchers at UCSF have developed a new method for emulsifying droplet libraries that is highly scalable. In the past decade, droplet microfluidic technology has revolutionized the sequencing space via single cell RNA-sequencing (scRNA-seq). This technology has vastly increased the resolution of RNA...

Published: 7/6/2023 | Inventor(s): Adam Abate, Daniel Weisgerber

Keywords(s): Digital Droplet PCR, Emulsification, High Throughput Screening, ScRNA-seq

Category(s): Technology Classifications > Biology

QUANTIFICATION OF CELLULAR PROTEINS USING BARCODED BINDING MOIETIES

QUANTIFICATION OF CELLULAR PROTEINS USING BARCODED BINDING MOIETIES Researchers at Stanford have developed a method enabling quantification of intracellular protein levels using oligonucleotide-barcoded antibodies. Multiplexing single cell technologies affords researchers the ability to characterize cell states and identify gene regulatory programs...

Published: 3/17/2023 | Inventor(s): William Greenleaf, Amy Chen

Keywords(s): Affinity Reagent, Antibody, Biomolecules, Integrated Screening System, ScRNA-seq, Single Cell, Single Cell Analysis, Single Cell Genomics, Single Cell RNA Sequencing, Single-cell Transcriptomics

Category(s): Technology Classifications > Biology

MICROFLUIDIC CELL BARCODING AND SEQUENCING

MICROFLUIDIC CELL BARCODING AND SEQUENCING Researchers at UC Berkeley have developed µCB-seq, a microfluidic cell barcoding and sequencing platform for high-resolution imaging and sequencing of single cells. Single-cell RNA sequencing (scRNA-seq) enables the investigation of complex biological processes in multicellular organisms with high...

Published: 3/17/2023 | Inventor(s): Aaron Streets, Tyler Chen, Anushka Gupta

Keywords(s): Fluorescence, Genetic Dissection, Microfluidics, ScRNA-seq, Single Cell, Single Cell Analysis, Single Cell Genomics, Single Cell RNA Sequencing, Single-cell Transcriptomics

Category(s): Technology Classifications > Biology

MULTI-PARAMETRIC SINGLE CELL ANALYSIS USING SPECTRALLY ENCODED MICROBEADS

MULTI-PARAMETRIC SINGLE CELL ANALYSIS USING SPECTRALLY ENCODED MICROBEADS Researchers at Stanford and the Chan Zuckerberg Biohub have developed methods for multiple parameter single cell analysis. Methods to analyze single cells are important for evaluating cell-to-cell variability in biological systems, especially where the characteristics of minority...

Published: 3/17/2023 | Inventor(s): Polly Fordyce, Kara Brower, Alexandera Sockell, Adam White, Yinnian Feng

Keywords(s): Biomolecules, Fluorescence, Microfluidics, RNA-seq, ScRNA-seq, Single Cell, Single Cell Analysis

Category(s): Technology Classifications > Biology