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Fast, Accurate Measurement of the Worker Populations of Honey Bee Colonies
Invention Description Assessing honeybee worker populations is a critical index for monitoring colony health, productivity, and survivability in both agricultural and natural ecosystems. While essential for hive management, traditional population measurement techniques remain the industry standard despite being inherently labor-intensive and disruptive...
Published: 2/2/2026   |   Inventor(s): Jun Chen, Junmin Zhong, Jon Harrison
Keywords(s): Agriculture and Animal Science
Category(s): Agriculture/Animal Health, Artificial Intelligence/Machine Learning, Life Science (All LS Techs)
A Novel Selective HDAC11 Inhibitor with Broad Anti-Cancer Efficacy
HDAC11 is a Histone Deacetylase (HDAC) enzyme. However, HDAC11 has a high defatty-acylase activity while its deacetylation activity is virtually nonexistent, which is linked to poor prognosis in multiple cancers. This suggests that inhibition of HDAC11 can be used to treat cancers by modulating protein function. No potent and selective inhibitors for...
Published: 2/2/2026   |   Inventor(s): Edward Seto, Hening Lin
Keywords(s):  
Category(s): Technology Classifications > Therapeutics > Small Molecules
Frequency-Selective Topological Wave Switches Using Anti-Resonance Control
This technology is a materials-based method of controlling acoustic wave propagation using anti-resonance control. By integrating phase-change inclusions into acoustic metamaterials, this technology provides a material that allows bidirectional signal transport at certain frequencies and only unidirectional transport at other specific anti-resonance...
Published: 2/2/2026   |   Inventor(s): Samarjith Biswas, Pierre Deymier, Keith Runge, Pierre Lucas
Keywords(s):  
Category(s): Technology Classifications > Engineering & Physical Sciences > Photonics
Inhibitory Monoclonal Antibodies Against Factor XII(a) and Method of use for Treatment of Dilated Cardiomyopathy and Heart Failure
This invention details how to make and utilize monoclonal antibodies that bind to and inhibit the activity of the coagulation factor Factor XII (FXII, FXIIa) protein, and methods of use for treatment of dilated cardiomyopathy and heart failure. Background: Approximately 6.7 million Americans over 20 years of age experience heart failure, and the prevalence...
Published: 2/2/2026   |   Inventor(s): Inna Gladysheva, Guy Reed
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Life Sciences > Biologics, Technology Classifications > Life Sciences > Therapeutics
Zernike Mode Sorting with Vortex Phase Filtering
This invention uses vortex filters, used in conjunction with single-mode converters, to spatially sort real and complex-valued Zernike polynomials and function as an arbitrary spatial mode sorter. Background: Optical systems rely on the precise manipulation of complex light fields. Conventional wavefront sensing and mode decomposition techniques...
Published: 2/2/2026   |   Inventor(s): Jacob Trzaska, Amit Ashok
Keywords(s):  
Category(s): Technology Classifications > Engineering & Physical Sciences > Photonics, Technology Classifications > Engineering & Physical Sciences > Quantum, Technology Classifications > Imaging & Optics > Telecommunications
Soft, Stretchable Electrical Tissue Adhesive for Precision Biosensing and Bioelectronic Device Integration
Executive Summary In-situ biosensing is a rapidly advancing field, enabling real-time biomolecular detection directly at local tissue sites. However, the integration of biosensors with soft, wet, and deformable tissues remains a key technical challenge. MSU researchers have created an electrical tissue adhesive (ETA) that forms fast, robust adhesive...
Published: 2/2/2026   |   Inventor(s): Shaoting Lin, Tsz Hung Wong, Jiabin Liu, Xinyue Liu, Yijie Cheng
Keywords(s): Bioadhesive, Bioelectronic, Electrochemical Sensor
Category(s): Medical, Advanced Materials
3D-Printed Microrobots for Magnetic Actuation, Imaging, and Hyperthermia
Executive Summary Microrobots offer transformative potential in biomedical applications, including targeted drug delivery, detoxification, and minimally invasive surgeries. However, two key challenges hinder their clinical translation: achieving scalable and precision fabrication, and enabling non-invasive imaging and tracking within deep biological...
Published: 2/2/2026   |   Inventor(s): Jinxing Li, Liuxi Xing
Keywords(s): 3D, Imaging, Medical
Category(s): Medical, Advanced Materials
Exploiting Vulnerabilities and Security Threats in Retrieval-Augmented Generative Models: The LIAR Attack Framework
Invention Description Retrieval-Augmented Generative (RAG) models boost generative AI’s accuracy by connecting large language models (LLMs) with the most current, external, knowledge sources. RAG models are widely used in fact-checking, information retrieval, and AI-driven search engines. Despite their utility, adversarial threats can exploit...
Published: 1/30/2026   |   Inventor(s): Zhen Tan, Chengshuai Zhao, Raha Moraffah, Huan Liu
Keywords(s): Artificial Intelligence, Data Mining, Large Language Models, Machine Learning, Natural Language Processing
Category(s): Artificial Intelligence/Machine Learning, Cybersecurity, Computing & Information Technology, Intelligence & Security, Physical Science
Supercharged fluorescent protein biosensors for real-time lanthanide monitoring
Background Rare earth elements—particularly lanthanides like terbium, thulium, and dysprosium—are essential to technologies underpinning renewable energy, electrified transportation, high-performance magnets, and medical imaging. As demand accelerates, sustainable extraction and recycling processes require precise monitoring of these valuable...
Published: 1/30/2026   |   Inventor(s): Andrew Ellington, Kevin Huang, David Walker
Keywords(s):  
Category(s): Life sciences > Research tools > Tool/assay/screening platform, Physical sciences > Environmental & sustainable solutions
Genetically engineered microbes for resilient biomanufacturing in space environments
Background As space missions grow longer and more complex, the need for sustainable biomanufacturing systems becomes increasingly urgent. Biological production of materials, nutrients, and pharmaceuticals offers a self-sufficient approach to supporting human exploration and settlement beyond Earth. However, wild-type microorganisms used in terrestrial...
Published: 1/30/2026   |   Inventor(s): Hal Alper, Mayur Bansal, Sangdo Yook
Keywords(s):  
Category(s): Life sciences > Metabolic engineering
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