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Non-Linear Single-Molecule FRET
1. Technology Overview The invention introduces a novel method for measuring the relative orientation of donor-acceptor (D-A) pairs in fluorescence resonance energy transfer (FRET) microscopy. This method leverages non-linear spectroscopy and phase-tagged photon counting to achieve precise measurements of the relative orientation and distance between...
Published: 12/31/2025   |   Inventor(s): Andy Marcus, Claire Albrecht
Keywords(s):  
Category(s): Imaging, Diagnostics
Surface Functionalization of Polyurethane Foams for Enhanced Oil Absorption
Invention Description In the global market, polyurethanes (PU) are seeing a surge in popularity, particularly in the form of covalently crosslinked microcellular foams, known as polyurethane foams (PUF). These PUF materials have emerging applications in various crucial sectors such as construction, infrastructure, foam mattresses, and insulation. However,...
Published: 12/29/2025   |   Inventor(s): Kamyar Karimi Nikoo, Timothy Long, Cameron Pascoe
Keywords(s):  
Category(s): Advanced Materials/Nanotechnology, Environmental Remediation/Wastewater Treatment, Physical Science
The Neutron Activation Reactor, Lithium (NARLi)
The Neutron Activation Reactor, Lithium (NARLi), generates clean electricity by using low-energy neutrons to activate lithium-7, producing heat without nuclear fission or long-lived radioactive waste, and can use recycled lithium from batteries as fuel. Background: Nuclear energy has long been recognized as a powerful means of generating large-scale...
Published: 12/29/2025   |   Inventor(s): Matthew Szydagis, Eric Bentsen
Keywords(s): energy, Technologies
Category(s): Campus, Campus > University at Albany, Technology Classifications > Clean Energy
App for perinatal mood and anxiety disorder intervention
A mobile digital application that uses a cognitive behavioral theory (CBT) model to help individuals struggling with perinatal mood and anxiety disorders. Background: Approximately 10-24% of women report peripartum mood and anxiety disorders (PMADs) as a complication of pregnancy. Untreated PMADs have devastating outcomes on the physical and mental...
Published: 12/26/2025   |   Inventor(s): Seethalakshmi Ramanathan, Rahul Bhatt
Keywords(s): anxiety, CBT, depression, perinatal, Technologies
Category(s): Technology Classifications, Technology Classifications > Computer Software
Enhancing Urban UAV Operations with Multi-Dimensional Fiducial Markers for Safety, Security, and Adaptability
Invention Description UAVs rely on fiducial markers, such as AprilTag or Aruco, to help with navigation and precision landing under GPS-denied environments. However, these markers are facing significant limitations in dense urban environments from adverse weather conditions, low visibility, urban clutter as well as security risks from tampering. These...
Published: 12/24/2025   |   Inventor(s): Dajiang Suo, Manuel Garcia, Marco Vincenzi, Shaozu Ding
Keywords(s):  
Category(s): Cybersecurity, Physical Science, Intelligence & Security, Applied Technologies, Wireless & Networking
Kulkarni/ Sprayable polymeric scaffold loaded with inflammasome-inhibiting lipid nanorods for anti-inflammatory therapy
­PRODUCT OPPORTUNITIES •Topical treatment for Psoriasis & Inflammatory Skin Conditions •Advanced drug delivery solutions PRODUCT OPPORTUNITIES COMPETITIVE ADVANTAGES •Sprayable formulation ensures easy application, even distribution, improving adherence and convenience •​​​​​​​Targeted therapy with...
Published: 12/24/2025   |   Inventor(s): Ashish Kulkarni, Dhanashree Surve
Keywords(s):  
Category(s): Healthcare, Material science, Nanotechnology, Therapeutics & prevention, Life Sciences
Generation of Therapeutic Human Anti-Trop-2 Extracellular Domain Antibodies (UCLA Case No. 2026-026)
UCLA researchers from the Department of Molecular and Medical Pharmacology and the Department of Microbiology, Immunology and Molecular Genetics have developed a panel of human antibodies and chimeric antigen receptors targeting Trop-2, providing diagnostic and therapeutic resources for targeting Trop2-driven cancer. BACKGROUND: Trophoblast cell surface...
Published: 12/23/2025   |   Inventor(s): Tanya Stoyanova, Owen Witte
Keywords(s):  
Category(s): Diagnostic Markers > Cancer, Diagnostic Markers > Targets And Assays, Life Science Research Tools > Antibodies, Therapeutics > Oncology, Therapeutics > Immunology And Immunotherapy
Combinatorial RNA-LNP Immunotherapy for Enhanced Pattern Recognition Receptor (PRR) Engagement, Targeted Dendritic Cell (DC) Activation, and Versatile (UCLA Case No. 2025-237)
UCLA researchers in the Department of Molecular and Medical Pharmacology have developed a cancer immunotherapy platform that uses lipid nanoparticle (LNP) delivery of modified RNA constructs to activate dendritic cells, enhance CD8+ T-cell priming, and drive potent anti-tumor immunity. BACKGROUND: Effective cancer immunotherapy requires robust activation...
Published: 12/23/2025   |   Inventor(s): Caius Radu
Keywords(s):  
Category(s): Therapeutics > Oncology, Therapeutics > Vaccines, Therapeutics > Infectious Diseases
VIBRATION BASED METHOD TO ESTIMATE VISCOSITY AND DENSITY OF FLUIDS AND SOFT-SOLIDS
VAlue proposition In various applications there is a need for viscosity and density measurements of fluids and solids. Resonant sensors for the measurement of rheological properties are often employed in process and condition monitoring. Micro-acoustic MEMS devices such as micro-cantilevers and SAW devices have been previously used for such applications....
Published: 12/23/2025   |   Inventor(s): Sunil Chakrapani, Sarthak Desai
Keywords(s):  
Category(s): Agriculture, Chemicals, Manufacturing Equipment, Test and Measurement
Fire-proof Li-ion batteries enabled by a zeolite separator and a fire-resistant electrolyte
Invention Description Lithium-ion batteries serve as energy-storage media for electric vehicles, grid-scale storage systems, mobile communication devices, and equipment used in hazardous environments. However, existing lithium-ion batteries cannot yet be produced at low cost, in a scalable manner, while also meeting the requirement of being free from...
Published: 12/23/2025   |   Inventor(s): Jerry Lin, Kishen Rafiz
Keywords(s):  
Category(s): Physical Science, Energy & Power, Applied Technologies
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