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Device For Rapid, Tunable, And Scalable Generation Of Lipid Nanoparticle Formulations

Microfluidic device for generation of large, precisely-defined, diverse lipid nanoparticle libraries for screening LNP formulations. Problem: Lipid nanoparticles (LNPs) have broad applications such as delivery agents for gene editing cargo, immunotherapies, and many clinical applications. The structures of the lipid components of an LNP, their relative...

Published: 4/17/2026 | Updated: 4/17/2026 | Inventor(s): Michael Mitchell, David Issadore, Andrew Hanna

Keywords(s): Bioengineering, Drug Delivery, Gene Editing, Gene Therapy, Immunology, Immunotherapy, Microfluidics, Nanotechnology

Category(s): Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Hardware & Components, Technology Classifications > Robotics

PEG-Based Antiscalants for Mitigating Silica Scaling in Membrane Distillation

Invention Description Silica scaling is a major challenge in membrane distillation systems, where the buildup of silica deposits can reduce efficiency and damage membranes over time. Existing antiscalants are often evaluated using static testing methods that do not fully capture how molecular structure influences performance under real operating conditions....

Published: 4/17/2026 | Updated: 4/17/2026 | Inventor(s): Tiezheng Tong

Keywords(s):

Category(s): Advanced Materials/Nanotechnology, Environmental, Physical Science

Liposomal Vancomycin-Cefazolin Nanoparticle for Treating Infections

A novel liposomal nanoparticle delivering vancomycin and cefazolin enhanced with targeting ligands improves treatment efficacy of Staphylococcus aureus infections, including MRSA, while reducing kidney toxicity. Technology Summary “Methicillin-resistant Staphylococcus aureus (MRSA) represents one of the most significant...

Published: 4/17/2026 | Updated: 4/17/2026 | Inventor(s): Arun Iyer, Michael Rybak, Samaresh Sau, Ketki Bhise, Razie Kebriael

Keywords(s):

Category(s): Technology Category > Life Science, Technology Category > Drug Delivery, Technology Category > Infectious disease, Technology Category > Driving Lifelong Health

Cryogenic Tank Interior Coating for Reducing Propellant Boil-Off

Produces Desired Surface Topology and Finish of Cryogenic propellant storage tank Interior Surfaces to Enable Spacecrafts to Conserve Cryogenic Fuel During Long‑Duration Missions and Reduced Gravity Environments This parylene C coating reduces the cryogenic propellant loss by coating the interior walls of cryogenic storage tanks to lower the boil-off...

Published: 4/17/2026 | Updated: 4/17/2026 | Inventor(s): Jacob Chung, Jimmy Almacddissi

Keywords(s):

Category(s): Technology Classifications > Engineering > Materials, Technology Classifications > Engineering > Mechanical, Technology Classifications > Engineering

Polyamine-Based Therapeutic Approach for Alopecia Areata

Executive Summary: Oral administration of DFMO (Eflornithine), a polyamine inhibitor, offers a novel treatment to reduce elevated polyamine levels and stimulate hair regrowth in alopecia areata patients. Description: Alopecia areata is an autoimmune hair loss disorder that affects approximately 5 million patients in the United States. Laboratory...

Published: 4/17/2026 | Updated: 4/17/2026 | Inventor(s): Andre Bachmann, Caleb Bupp

Keywords(s):

Category(s): Medical, Pharmaceutical, Therapeutic

Small Molecule Inhibitors of Pleckstrin-2 for Treating Myeloproliferative Neoplasms

SHORT DESCRIPTION Small molecule inhibitors of Pleckstrin-2 (Plek2) for treating cell proliferative diseases and disorders, particularly myeloproliferative neoplasms (MPNs). NU Tech IDs: NU 2018-169, NU 2021-005 PRINCIPAL INVESTIGATOR Peng Ji Northwestern University Feinberg School of Medicine, Department of Pathology IP...

Published: 4/16/2026 | Updated: 4/16/2026 | Inventor(s):

Keywords(s): Breast cancer, Cancer/Oncology, Colon cancer, Leukemia, Lung cancer, Pancreatic cancer, Small molecule, Therapeutics

Category(s): Life Sciences > Therapeutics

AI-driven Analog-to-Digital Converter (ADC) Design Automation

Invention Description Designing high-performance analog circuits, such as analog-to-digital converters (ADCs), is a complex and time-intensive process that typically requires significant expert knowledge and manual tuning. Traditional design methods rely heavily on iterative trial-and-error, making it difficult to efficiently meet strict performance...

Published: 4/16/2026 | Updated: 4/16/2026 | Inventor(s): Arindam Sanyal, Imon Banerjee, Zuwei Guo, Shamma Nasrin

Keywords(s):

Category(s): Manufacturing/Construction/Mechanical, Physical Science, Semiconductors, Materials & Processes, Semiconductor Devices

Benzofuranoindoline-Containing Fungal RiPP-Derived Anticancer Compounds

Benzofuranoindoline-containing fungal RiPP-derived compounds and analogs, plus pharmaceutical compositions, and administration methods for treating cancers, including leukemia. Problem: The disclosure targets diseases and disorders where new therapeutic compounds are needed, including cancers such as leukemia. Fungal ribosomally synthesized and post-translationally...

Published: 4/16/2026 | Updated: 4/16/2026 | Inventor(s): Xue Sherry Gao, Hans Renata, Qiuyue Nie

Keywords(s): Oncology, Small Molecule

Category(s): Technology Classifications > Therapeutics

Integrated Chemical-Looping System for High-Purity Hydrogen Generation

Delivers On-Site Methane-Derived Hydrogen While Simultaneously Supplying CO and N2, Eliminating External Oxygen-Separation and Heating This integrated chemical-looping system delivers on-site methane-derived hydrogen and simultaneously supplies pure CO and N2, eliminating the need for external oxygen separation or downstream separations and external...

Published: 4/16/2026 | Updated: 4/16/2026 | Inventor(s): Jonathan Scheffe, Kathryn Trimm

Keywords(s):

Category(s): Technology Classifications > Engineering > Chemical, Technology Classifications > Engineering > Materials

Polymers of Intrinsic Microporosity for Improved Smart Device and Display Technologies

Electrochromic Devices Rapidly Changing Color for Supercapacitive and Pseudocapacitive Energy Storage These polymers of intrinsic microporosity (PIMs) use electrochromic materials that change color in response to an applied voltage for improved energy storage. Electrochromic materials switch color when a voltage potential is applied. These materials...

Published: 4/16/2026 | Updated: 4/16/2026 | Inventor(s): Austin Evans, Mahmudul Hasan, Rupam Roy, Kiana Treaster, Kaitlin Slicker, Ani Davis, Dibakar Das

Keywords(s):

Category(s): Technology Classifications > Engineering > Chemical, Technology Classifications > Engineering > Materials

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