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Selective Receptor Modulators for Skin Depigmentation
Small-molecule compositions modulate non-canonical sex steroid receptors to decrease, prevent, or reverse skin pigmentation gain in mammalian subjects. Problem: Skin hyperpigmentation can arise from pregnancy, hormones, inflammatory conditions, or skin injury. Existing approaches may not address receptor pathways that regulate melanocyte pigmentation....
Published: 4/6/2026
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Updated: 4/6/2026
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Inventor(s):
Todd Ridky
,
Christopher Natale
Keywords(s):
Dermatology
,
Small Molecule
Category(s):
Technology Classifications > Therapeutics
Portable Perfusion Apparatus for Ex Vivo Tissue
A portable perfusion apparatus that cycles perfusate through ex vivo vertebrate tissues, enabling field deployment for preservation and training. Problem: Amputated extremities can lose viability before reattachment, especially in remote or traumatic settings. Existing perfusion machines may be too large for rapid deployment and are often limited to...
Published: 4/6/2026
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Updated: 4/6/2026
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Inventor(s):
Edward Cantu
,
Rikesh Gandhi
,
Lawrence Levin
,
Jason Wink
,
Matthew Winterton
Keywords(s):
Orthopedics
,
Surgery
Category(s):
Technology Classifications > Medical Devices
A Fast and Accurate Computational Method for Radiation Treatment Planning
A computational method for calculating the dose, Linear Energy Transfer and Relative Biological Effectiveness of proton treatment planning and optimization. Problem: In radiation therapy, the dose absorbed by cells determines their probability of survival. However, the biological effectiveness of the dose can vary. Multiple factors influence this variability,...
Published: 4/6/2026
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Updated: 4/6/2026
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Inventor(s):
Alejandro Carabe Fernandez
,
Alejandro Bertolet Reina
,
Miguel Cortes Giraldo
Keywords(s):
Oncology
,
Platform Technology
,
Radiology
Category(s):
Technology Classifications > Testing & Measurement
,
Technology Classifications > Imaging
,
Technology Classifications > Medical Devices
A Precise and Effective Method of Proton Beam Therapy for Cancer Treatment
A method of proton beam therapy using a single energy proton beam delivered at multiple angles to the tumor. Problem: Proton therapy is a type of radiation treatment that uses high-energy protons to damage and kill cancer cells. To maximize therapeutic efficacy while limiting collateral damage to healthy cells, proton pencil beams are delivered from...
Published: 4/6/2026
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Updated: 4/6/2026
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Inventor(s):
Alejandro Carabe Fernandez
Keywords(s):
Oncology
,
Platform Technology
,
Radiology
Category(s):
Technology Classifications > Imaging
,
Technology Classifications > Medical Devices
Next-Generation Photothermal Nanoagent for Safe Systemic Tumor Ablation
A resonance energy transfer (RET)–engineered nanoplatform enabling complete tumor ablation using near-infrared irradiation Background Photothermal therapy (PTT) uses NIR light to generate localized tumor heating. However, many systems require elevated laser power densities to achieve therapeutic temperatures, limiting translational feasibility....
Published: 4/3/2026
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Updated: 4/3/2026
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Inventor(s):
Oleh Taratula
,
Olena Taratula
,
Prem Singh
Keywords(s):
Category(s):
Therapeutics
,
Medical Devices
Multipurpose Ultra-strong Heat Resistant Aluminum Alloys for Additive Manufacturing
Multipurpose Ultra-strong Heat Resistant Aluminum Alloys for Additive Manufacturing NU 2025-019 INVENTORS David Seidman* Amir Rezaei Farkoosh SHORT DESCRIPTION This technology comprises a series of ultra-high-strength, precipitation-hardened aluminum alloys specifically designed for laser additive manufacturing. The alloys deliver exceptional...
Published: 4/3/2026
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Updated: 4/3/2026
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Inventor(s):
Keywords(s):
3D Printing/Additive Manufacturing
,
Manufacturing/Processing
,
Metals
Category(s):
Physical Sciences > Materials and Industrial Processes
,
Physical Sciences > Engineering & Technology
Guidewire Delivery Device
Project ID: D2026-24 Background The advancement and placement of surgical guidewire, as well as other medical apparatuses, can be a strenuous and time-consuming process for clinicians during various types of surgery and medical procedures. When it takes extended amounts of time to perform a procedure, complications can occur that can be detrimental...
Published: 4/2/2026
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Updated: 4/2/2026
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Inventor(s):
Nabeel Khatri
,
Claire Ellerbrock
,
Dylan Aultman
,
Gangesh Sharma
,
Graham Hauge
Keywords(s):
Category(s):
Device
,
Medical Device
Harvesting and Immobilization of Heavy Metals
Invention Description The scarcity of fertile land and water, driven by erosion, pollution, and heavy metal toxicity, represents a critical threat to global food security and environmental health. Heavy metals are non-biodegradable and persist in the soil for a very long time. With a significant portion of global soil resources at risk by 2050, particularly...
Published: 4/1/2026
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Updated: 4/1/2026
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Inventor(s):
Elham Fini
,
Eric Evans
,
Farideh Pahlavan
Keywords(s):
Category(s):
Environmental
,
Environmental Remediation/Wastewater Treatment
,
Physical Science
A Low-Cost Non-invasive Fruit Ripeness Sensing System (Case No. 2025-007)
Summary: Researchers in the Department of Computer Science at UCLA developed an affordable, non-invasive fruit ripeness estimation system to improve operational efficiency of food manufacturing systems. Background: Fruit waste accounts for a significant portion of global waste due to consumer purchasing trends and grower harvesting issues. Consumers...
Published: 4/1/2026
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Updated: 4/1/2026
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Inventor(s):
Omid Abari
,
Shanmu Wang
Keywords(s):
acoustics
,
Agriculture
,
Cellular agriculture
,
Continuous-Wave Radar
,
frequency modulation
,
millimeter-wave
,
mmWave backscatter network
,
Radiofrequency Ablation
Category(s):
Software & Algorithms > Data Analytics
,
Optics & Photonics
,
Optics & Photonics > Remote Sensing
,
Software & Algorithms
,
Software & Algorithms > Artificial Intelligence & Machine Learning
,
Software & Algorithms > AI Algorithms
A Neuro-Symbolic Calculus for Quantifying Security Posture in Microservice Architecture
This technology is a holistic, system-level method for quantifying and explaining the security posture of cloud-native applications built with microservice architectures. To overcome the fragmented observability problem, it analyzes how requests traverse network boundaries across multiple services, generating a multi-dimensional security posture result...
Published: 4/1/2026
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Updated: 4/1/2026
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Inventor(s):
Tomas Cerny
,
Shakthi Weerasinghe
Keywords(s):
Category(s):
Technology Classifications > Software & Information Technology > Security
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