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Netrin-1 mimetic peptide amphiphiles
Netrin-1 Mimetic Peptide Amphiphile Assemblies NU 2024-174 INVENTORS Samuel Stupp* Cara Smith Zaida Alvarez Pinto SHORT DESCRIPTION Nanofiber-shaped supramolecular assemblies that mimic netrin-1 bioactivity to stimulate neurite growth and synaptic maturation for enhanced CNS regeneration. BACKGROUND Neurotrophic factors are essential for...
Published: 2/20/2026
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Inventor(s):
Keywords(s):
AD - Alzheimer’s Disease
,
CNS - Central Nervous System
,
CVA - Cerebrovascular Accident
,
Nanomaterials
,
Nanotechnology
,
Neurodegenerative disease
,
Regenerative medicine
,
SCI - Spinal cord injury
,
Targeted therapy
,
Therapeutics
Category(s):
Life Sciences > Therapeutics
Diamond Needle Insertion Technique for High Thermal Conductivity Through-Glass Vias (TGVS) Interposers (Case No. 2026-157)
Summary: UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a novel method for producing electrically insulating, high–thermal conductivity through-glass vias. Background: Advanced semiconductor systems rely on 3D integrated circuits (3DICs) to meet rising demands for higher performance, reduced form...
Published: 2/20/2026
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Inventor(s):
Tiwei Wei
Keywords(s):
3D integrated circuits (3DIC)
,
advanced semiconductor packaging
,
artificial intelligence accelerators
,
Composite Material
,
copper electroplating
,
cubic-octahedral diamond
,
diamond composites
,
diamond metallization
,
Doping (Semiconductor)
,
Electronics & Semiconductors
,
ferromagnetic semiconductor
,
Functional Materials
,
functional/composite materials
,
glass interposers
,
high-performance computing
,
Microelectronics Semiconductor Device Fabrication
,
microfabrication
,
Organic Semiconductor
,
physical vapor deposition (PVD)
,
Semiconductor
,
semiconductor chip foundries
,
Semiconductor Device
,
Semiconductor Device Fabrication
,
Semiconductor Ohmic Contact
,
Semiconductor Risk Assessment
,
Semiconductor Sapphire
,
Semiconductors
,
silicon interposers
,
thermal bottleneck
,
through-glass vias (TGVs)
Category(s):
Materials
,
Materials > Composite Materials
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Materials > Functional Materials
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Materials > Semiconducting Materials
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Materials > Metals
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Materials > Nanotechnology
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Electrical
,
Electrical > Electronics & Semiconductors
Through-Glass Vias (TGVS) Thermal Management Using Diamond-Assisted Copper Metallization for Advanced 3DIC Packaging (Case No. 2026-156)
Summary: UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a novel approach to enhance the thermal performance of through-glass vias for advanced semiconductor packaging. Background: Advanced semiconductor systems rely on 3D integrated circuits (3DICs) to meet rising demands for higher performance, reduced...
Published: 2/20/2026
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Inventor(s):
Tiwei Wei
,
Ye Yang
Keywords(s):
3D integrated circuits (3DIC)
,
advanced semiconductor packaging
,
artificial intelligence accelerators
,
copper electroplating
,
cubic-octahedral diamond
,
diamond composites
,
diamond metallization
,
Doping (Semiconductor)
,
Electronics & Semiconductors
,
ferromagnetic semiconductor
,
functional/composite materials
,
glass interposers
,
heat dissipation
,
high-performance computing
,
Microelectronics Semiconductor Device Fabrication
,
microfabrication
,
Organic Semiconductor
,
physical vapor deposition (PVD)
,
real-time thermal management
,
Semiconductor
,
semiconductor chip foundries
,
Semiconductor Device
,
Semiconductor Device Fabrication
,
Semiconductor Ohmic Contact
,
Semiconductor Risk Assessment
,
Semiconductor Sapphire
,
Semiconductors
,
silicon interposers
,
thermal bottleneck
,
thermal management
,
thermal management systems
,
through-glass vias (TGVs)
,
zzsemiconducting materials
Category(s):
Chemical
,
Chemical > Industrial & Bulk Chemicals
,
Chemical > Synthesis
,
Chemical > Chemical Processing & Manufacturing
,
Electrical
,
Electrical > Computing Hardware
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Electrical > Electronics & Semiconductors
,
Materials
,
Materials > Metals
,
Materials > Semiconducting Materials
,
Materials > Functional Materials
,
Materials > Fabrication Technologies
,
Materials > Composite Materials
,
Software & Algorithms > Communication & Networking
Enhancers for gene delivery to specific motor neuron subtypes
Enhancers demonstrating motor neuron subtype specificity Invention Summary: Specific types of motor neurons become dysfunctional and degenerate in motor neurons diseases like amyotrophic lateral sclerosis and Charcot Marie tooth syndrome. To reduce the risk of toxicity from ubiquitous or non-specific expression of gene therapies, there is...
Published: 2/20/2026
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Inventor(s):
Tulsi Patel
,
Yijia Chen
Keywords(s):
Category(s):
Technology Classifications > Healthcare & Life Sciences
Integrating AI in Back Injury Prevention
This wearable technology integrates sensors into a back brace and shoe inserts to monitor posture and movement. Using AI-driven analysis, it provides real-time feedback via a software application, helping Direct Care Workers prevent the risk of back injuries during lifting and transfer tasks. Background: Workplace injuries, particularly musculoskeletal...
Published: 2/20/2026
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Inventor(s):
Yuchi Young
Keywords(s):
Technologies
Category(s):
Campus > University at Albany
,
Technology Classifications > Artificial Intelligence
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Technology Classifications > Healthcare
Negative Autoregulation for Safe Cas13-Based RNA Therapeutics
Mitigates Collateral RNA Damage in Repeat Expansion Disorders These negative autoregulatory approaches enable safe Cas13-based RNA therapeutics for mitigating collateral RNA damage when treating repeat expansion disorders. CRISPR-Cas13d is an enzyme in the CRISPR family of genome editing tools. Cas13d has been shown to have immense therapeutic potential...
Published: 2/20/2026
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Inventor(s):
Eric Wang
,
Chase Kelley
Keywords(s):
Category(s):
Technology Classifications > Human Health Care > Therapeutics
,
Technology Classifications > Research Tools > Therapeutics
Electrotherapy for dental implants
In Situ electrochemical repassivation therapy of titanium dental implants can restore corrosion resistance and enhance cellular biocompatibility. Invention Summary: Commercially available titanium dental implants have a naturally formed protective titanium oxide (TiO2) passivation layer on their surfaces, which endows the implants with corrosion...
Published: 2/20/2026
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Inventor(s):
Georgios Kotsakis
,
Li Xie
Keywords(s):
Category(s):
Technology Classifications > Healthcare & Life Sciences
,
Technology Classifications > Dental
Distributed Neuromorphic Control
Advantages Significantly lowers power consumption by replacing continuous control updates with event-driven spike-based actuation Reduces communication load in multi-agent networks through sparse, asynchronous information exchange Delivers provable stability and guaranteed minimum inter-event timing to ensure reliable operation Enables scalable...
Published: 2/20/2026
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Inventor(s):
Tansel Yucelen
Keywords(s):
Artificial Intelligence
,
Internet of Things / IoT
,
Robotics
Category(s):
Technology Classifications > Computer Science > Algorithms
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Technology Classifications > Engineering > Sensors
Equine IL-31 Neutralizing Antibody for Treating Pruritic Skin Disease
Treats Allergic Itching in Horses by Specifically Blocking IL-31 Activity This equine IL-31 neutralizing antibody provides a targeted treatment for pruritic skin disease, relieving allergic itching in horses by specifically blocking IL-31 activity. Allergic skin conditions like atopic dermatitis and insect bite hypersensitivity trigger intense pruritus,...
Published: 2/20/2026
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Inventor(s):
Rosanna Marsella
,
Nicola Craig
Keywords(s):
Category(s):
Technology Classifications > Veterinary > Therapeutics
Balloon Catheters
Vacuum-Tooth Brush Attributes: On-off switch, Vaccum power (hi-low), Easy-Empty (or disposable) fluid & debris collector cup, Ergonomic design, Battery-operated and Affordable. Invention Summary: There is a need for a powered toothbrush that has a built-in pump and waste container that automatically removes the liquids from the...
Published: 2/20/2026
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Inventor(s):
Keywords(s):
Category(s):
Technology Classifications > Medical Devices
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