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RSA-Wearable Alertness Detecting Device (Case No. 2025-245)

Summary: UCLA researchers from the Department of Medicine-Pulmonary Disease have developed a novel wearable device to detect alertness and predict the onset of sleep for improved safety. Background: Hypersomnia and excessive daytime sleepiness (EDS) are both symptoms of a broad class of sleeping disorders including obstructive sleep apnea (OSA),...

Published: 12/1/2025 | Inventor(s): Ravi Aysola

Keywords(s): Biomonitoring, Computer Monitor, continuous sleep monitoring, CPAP, Gene Block, non-invasive monitoring, patient outcome, Philips, public health monitoring, remote monitoring, remote patient analysis, remote patient monitoring (RPM), Remote Sensing, sleep apnea, sleep monitoring, sleep monitoring and health, wearable, wearable electronics, wearable medical device, wearable medical devices, wearable sensors, wearable sensors for health

Category(s): Medical Devices, Medical Devices > Monitoring And Recording Systems, Medical Devices > Hospital Systems, Electrical, Electrical > Sensors, Electrical > Flexible Electronics, Platforms, Software & Algorithms, Software & Algorithms > Digital Health, Software & Algorithms > Data Analytics

Nanoparticle & dsDNA Toolkit for Decreased Toxicity and Gene Editing of Epithelial Stem Cells via Epithelial Disruption (UCLA Case No. 2023-205/209) -- for Cystic Fibrosis and other genetic diseases

UCLA researchers in the Department of Pediatrics, Hematology/ Oncology have constructed a nanoparticle toolkit for increased integration and reduced toxicity for gene therapies that treat debilitating diseases such as Cystic Fibrosis and other critical genetic diseases. BACKGROUND: Gene therapies are the forefront of therapeutic advancements as a one-off...

Published: 12/1/2025 | Inventor(s): Steven Jonas, Brigitte Gomperts, Donald Kohn

Keywords(s):

Category(s): Therapeutics > Gene Therapy And Editing, Platforms > Drug Delivery

High-Throughput Olfactometer System for Tracking Animal Responses to Olfactory and Visual Cues

Enables Precise Multimodal Stimulus Testing Using Odor and Visual Cues with Real-Time Automated Tracking This olfactometer system tracks animal responses to a variety of controllable olfactory cues and optionally simultaneously, with visual cues. Insect behavior plays a critical role in agriculture, disease transmission, and environmental monitoring....

Published: 12/1/2025 | Inventor(s): Thomson Paris, Xavier Martini, Robert Parsons

Keywords(s):

Category(s): Technology Classifications > Engineering > Instrumentation-Sensors-Photonics

Hyperbranched Polyglycerol Encapsulated Proteins for Oral Protein Delivery (Case No. 2012-425)

Patent Abstract: Methods for modifying therapeutic agents such as therapeutic biomolecules, such as proteins for improved oral, rectal or transmucosal delivery, as well as compositions made using such methods and methods of administering such compositions to a subject, are disclosed. Specifically, the therapeutic agents are conjugated to hyperbranched...

Published: 12/1/2025 | Inventor(s): Yunfeng Lu, Juanjuan Du, Jie Li, Yang Liu

Keywords(s):

Category(s): Platforms > Drug Delivery

Multi Polish Robot Polishing Method

This invention is for a robotic system that is designed to polish multiple regions of a large optical surface simultaneously. It includes a novel internal propulsion mechanism that uses coils to drive a magnetic weight along a circular track. This method can accelerate the mirror fabrication time, eliminating the need for off-line testing, reducing...

Published: 12/1/2025 | Inventor(s): Heejoo Choi, Kevin Derby, Casey Scoggins, Hyukmo Kang, Vipender Negi, Daewook Kim, Maxim Duque, Chaemin Lee

Keywords(s):

Category(s): Technology Classifications > Imaging & Optics > Optical Fab / Metrology, Technology Classifications > Imaging & Optics > Lens & System Design, Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation > Robotics

Antimicrobial bioactive glass-ceramic scaffold

Executive Summary Healing infected tissue and combating resistant bacteria are significant clinical challenges. Antibiotic-based therapies are increasingly unsuccessful due to the ability of pathogens to develop resistance. Methicillin resistant Staphylococcus aureus (MRSA), for example, is a leading cause of many infections, including skin and soft...

Published: 12/1/2025 | Inventor(s): Xanthippi Chatzistavrou, Neal Hammer

Keywords(s):

Category(s): Medical, Biotechnology, Pharmaceutical

Summary: UCLA researchers have developed a software algorithm for locally low-rank denoising that improves image quality and diagnostic reliability in multi-coil, multi-contrast MRI by correcting complex noise and preserving fine image details. Background: Magnetic resonance imaging (MRI) is a powerful, non-invasive tool widely used in both research...

Published: 12/1/2025 | Inventor(s): Shu-Fu Shih, Holden Wu

Keywords(s): 3D tissue imaging, AI-guided medical imaging, Biomedical Engineering, Cardiac MRI, Cine MRI, Deep learning MRI, DENSE MRI, Imaging, Magnetic Resonance Imaging, Magnetic Resonance Imaging Carotid Artery Stenosis, Magnetic Resonance Imaging Hypoxia (Medical), Magnetic Resonance Imaging Medical Physics, Magnetic Resonance Imaging Microangiopathy, Magnetic Resonance Imaging Pathology, Magnetic Resonance Imaging Spin Polarization, Medical artificial intelligence (AI), Medical Device, Medical Devices and Materials, Medical diagnostics, Medical Imaging, MRI, multiparametric MRI (mpMRI), radial MRI

Category(s): Electrical > Imaging, Electrical > Signal Processing, Life Science Research Tools > Research Methods, Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > MRI, Software & Algorithms > Image Processing, Software & Algorithms

A New Method for Dual Detection of Magnetic and Dielectric Signals from Core/Shell Nanoparticles for Advanced Biodetection and Diagnostics

Advantages Simultaneously detects magnetic and dielectric signals from core/shell nanoparticles with high sensitivity. Provides rapid, real-time biodetection in microfluidic systems using minimal sample volumes. Accurately differentiates healthy and cancer cells through enhanced signal responsiveness. Easily integrates into scalable biomedical...

Published: 12/1/2025 | Inventor(s): Manh-Huong Phan, Kee Young Hwang, T. Lee, Minh Nguyen, Supawitch Hoijang, Dakota Brown

Keywords(s): Biomarker, Nanotechnology, Sensors

Category(s): Technology Classifications > Electronics > Nanotechnology

Flexible Hybrid Fastener with Increased Bond Strength and Optimized Sealing Capacity

Executive Summary Fasteners are often installed through holes drilled in individual pieces to be joined. While significant advancements have been made in fasteners over the past several decades, construction techniques such as using composites (including wood, fiberglass, and carbon fiber), in particular, have exposed serious limitations to existing...

Published: 12/1/2025 | Inventor(s): Gary Cloud

Keywords(s):

Category(s): Advanced Materials, Defense, Mechanical, Subassemblies and Components, Energy

A Flexible, Scalable Platform Technology to Augment Antibiotic Efficacy

This invention relates to a novel, safe, and efficacious approach to reduce antibiotic concentrations required to kill pathogenic bacteria. The product thus augments antibiotic efficacy, including against bacteria that are clinically resistant. Background: One of the biggest risks to global public health is antibiotic resistance. Through processes...

Published: 12/1/2025 | Inventor(s): Gayatri Vedantam, Virinchipuram Viswanathan, Arun Sharma, David Stewart

Keywords(s):

Category(s): Technology Classifications > Healthcare Portfolios > Infectious Diseases, Technology Classifications > Life Sciences > Therapeutics

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