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Therapeutic backbone and scaffold modification in the physiological environment
This technology enables precise, water-based chemical modification of proteins at their C-terminus using a single, easily removable reagent, preserving protein structure and function and allowing attachment of diverse functional groups for therapeutic, research, and diagnostic applications. Background: Proteins and polypeptides play a central role...
Published: 12/19/2025   |   Inventor(s): Qiang Zhang
Keywords(s): antibody therapy, GLP-1 secretion, Insulin, protein engineering, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biomedical Science and Engineering
Enhanced Photosynthesis Efficiency for Improved Crop Productivity
Treats Plants with Mutated D1 Proteins to Boost Plant Growth Rates and Biomass This modified D1 protein enhances photosynthesis efficiency in plants, improving crop productivity and boosting overall growth rates and biomass. Photosynthesis is the fundamental process by which plants convert light energy into chemical energy, driving growth and biomass...
Published: 12/19/2025   |   Inventor(s): Xin Wang
Keywords(s):  
Category(s): Technology Classifications > Agricultural > Others
An Attenuated Vaccine for Lyme Disease
Project ID: TECH2026-05 Background Lyme disease is caused by the gram-negative spirochete Borrelia burgdorferi, as well as other Borrelia species within the Borrelia burgdorferi sensu lato group. B. burgdorferi is known to alter its virulence protein expression profiles depending on its environment. Numerous studies have shown environmental differences...
Published: 12/19/2025   |   Inventor(s): Ronald Wooten, John Presloid
Keywords(s):  
Category(s): Rare Disease
Dual-Genome Prediction Model for Black-Pod-Resistant Cacao
Integrates Host- and Pathogen-Genome Data in a Unified Pipeline to Evaluate Prediction Accuracy and Accelerate Breeding Decisions This dual-genome prediction model for black-pod-resistant cacao integrates host- and pathogen-genome data with phenotypic data, such as disease resistance ratings, in a unified pipeline, allowing for a detailed evaluation...
Published: 12/19/2025   |   Inventor(s): Jeremy Brawner, Ina Schlathoelter
Keywords(s):  
Category(s): Technology Classifications > Software > Others
Targeted Synthetic Photosynthesis Inhibitors for Herbicidal and Algicidal Applications
Inhibits Photosynthesis through Biochemical and Synthetic Biology Approaches for Weed, Algae, and Cyanobacteria Control/h3> These synthetic photosynthesis inhibitors for herbicidal and algicidal applications offer an effective solution for weed, algae, and cyanobacteria (blue-green algae) control. Agriculture faces significant challenges in weed...
Published: 12/19/2025   |   Inventor(s): Gilles Basset, Lauren Stutts, Scott Latimer
Keywords(s):  
Category(s): Technology Classifications > Agricultural > Others
Phenotyping Single Ventricle Physiology Using Electronic Health Records (Case Nos. 2025-322 and 2025-323)
Summary: UCLA researchers have created a cutting-edge, automated phenotyping tool that harnesses electronic health records to enable rapid and precise identification of single ventricle physiology (SVP), especially in neonatal and pediatric populations. Background: Single ventricle physiology (SVP) is a rare heart condition that develops before birth...
Published: 12/18/2025   |   Inventor(s): Kim-Lien Nguyen, William Hsu, Hang Xu
Keywords(s): Algorithm, cardiac cycle, Cardiovascular, Cardiovascular Disease, cardiovascular diseases, cardiovascular monitoring, cardiovascular prediction, Computer-Aided Diagnosis, heart disease mitigation, heart support, medical automation technology, Medical Device, medical device cardiac monitoring, Medical diagnostics, Medical Guideline, non-invasive cardiac monitoring, Smart medical device, Software, Software & Algorithms, Software Development Tools
Category(s): Diagnostic Markers, Medical Devices, Medical Devices > Cardiac, Medical Devices > Monitoring And Recording Systems
Engineering the Sodium/Iodide Symporter for Enhanced Targeted Internal Radiotherapy
Summary The Sodium/Iodide Symporter (NIS) is a critical protein that facilitates the active transport of iodide into thyroid cells, essential for synthesizing thyroid hormones. Recent advancements in engineering NIS variants aim to selectively transport oxyanions, offering innovative therapeutic strategies for cancer treatment in the thyroid and elsewhere...
Published: 12/18/2025   |   Inventor(s):  
Keywords(s):  
Category(s): Therapeutics
CIM24NUVA-03
CIM24NUVA-03 is an early maturing, high-yielding, drought tolerant, nutritious maize hybrid with orange grain that is biofortified with PVA and is NUE, resistant to GLS, TLB, Ear rots, and MSV, and bred for food use in tropical, rainfed, dry/wet mid-altitude and transition ecologies in southern Africa and similar agroecologies. General Information Target...
Published: 12/18/2025   |   Inventor(s):  
Keywords(s):  
Category(s): Biofortification > Provitamin A, Biotic Stress Tolerance > Ear rots, Biotic Stress Tolerance > Grey leaf spot (GLS), Biotic Stress Tolerance > Maize streak virus (MSV), Biotic Stress Tolerance > Turcicum leaf blight (TLB), Germplasm > Maize Germplasm, Grain Color > Orange grain, Maturity Group > Early maturing, Region > Southern Africa, Product Type > Three-way cross hybrid, Abiotic Stress Tolerance > Drought tolerant, Abiotic Stress Tolerance > Nitrogen-use efficient (NUE), Year announced > 2025, Grain Texture > Flint, Seed producibility traits > Good nicking
CIM24NUVA-01
CIM24NUVA-01 is an early maturing, high-yielding, drought tolerant, nutritious maize hybrid with orange grain that is biofortified with PVA and is NUE, resistant to GLS, TLB, Ear rots, and MSV, and bred for food use in tropical, rainfed, dry/wet mid-altitude and transition ecologies in southern Africa and similar agroecologies. General Information Target...
Published: 12/18/2025   |   Inventor(s):  
Keywords(s):  
Category(s): Grain Color > Orange grain, Germplasm > Maize Germplasm, Biotic Stress Tolerance > Ear rots, Biotic Stress Tolerance > Grey leaf spot (GLS), Biotic Stress Tolerance > Maize streak virus (MSV), Biotic Stress Tolerance > Turcicum leaf blight (TLB), Biofortification > Provitamin A, Abiotic Stress Tolerance > Drought tolerant, Abiotic Stress Tolerance > Nitrogen-use efficient (NUE), Maturity Group > Early maturing, Region > Southern Africa, Product Type > Three-way cross hybrid, Year announced > 2025, Grain Texture > Flint
CIM24SAPP1-I-05
CIM24SAPP1-I-05 is a high-yielding, intermediate-maturing maize hybrid with white grain and drought tolerance, that is NUE and resistant to GLS, TLB, ear rots, and MSV, suitable for food use in tropical, rainfed, dry/wet mid-altitude and transition ecologies in southern Africa and similar agroecologies. General Information Target...
Published: 12/18/2025   |   Inventor(s):  
Keywords(s):  
Category(s): Adaptation > Mid-altitudes, Biotic Stress Tolerance > Grey leaf spot (GLS), Biotic Stress Tolerance > Maize streak virus (MSV), Biotic Stress Tolerance > Turcicum leaf blight (TLB), Germplasm > Maize Germplasm, Grain Color > White grain, Grain Texture > Semi-dent, Maturity Group > Intermediate maturing, Region > Southern Africa, Seed producibility traits > Good nicking, Product Type > Three-way cross hybrid, Year announced > 2025, Abiotic Stress Tolerance > Drought tolerant, Abiotic Stress Tolerance > Nitrogen-use efficient (NUE), Biotic Stress Tolerance > Ear rots
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