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Structurally and Functionally Diverse Heterocyclic Dipeptide Isosteres and Their Derivatives as Antimicrobial Agents and Peptidomimetic Building Blocks

This technology enables rapid, modular synthesis of diverse heterocyclic dipeptide isosteres with potent antimicrobial activity, which can be easily incorporated into peptides to create stable, bioactive molecules for drug discovery and therapeutic applications. Background: The field of antimicrobial drug discovery and peptidomimetic development...

Published: 5/4/2026 | Updated: 5/4/2026 | Inventor(s): Sujit Suwal, Olga Novikova

Keywords(s): antibacterial, Bioactive heterocyclic amino esters and peptidomimetics, Chemo-selective synthesis of heterocyclic amino esters, iterative Buchwald Hartwig amination and Suzuki coupling, Technologies

Category(s): Campus > Buffalo State College, Technology Classifications > Drug Design and Synthesis

A layer-by-layer mass spectrometry intensity method for de novo direct sequencing of RNA therapeutics and impurities

3D NGMS-Seq is a mass spectrometry-based technology that accurately sequences all RNA types and impurities in mixed samples, enabling comprehensive analysis of RNA therapeutics for drug development, quality control, and regulatory compliance. Background: The field of RNA-based therapeutics has experienced rapid growth due to the success of mRNA vaccines...

Published: 5/4/2026 | Updated: 5/4/2026 | Inventor(s): Shenglong Zhang

Keywords(s): Mass spectrometry imaging, Technologies

Category(s): Campus > University at Albany, Technology Classifications > Bioinformatics, Technology Classifications > Therapeutics and Vaccines

Luna Rope

This technology is a static safety rope designed for use in lunar surface exploration. This safety rope has a central kern surrounded by a protective mantle similar to traditional climbing ropes. However, to withstand harsh lunar surface conditions, this rope is designed with an additional outer sheath made of Tyvek. Tyvek is currently the best known...

Published: 5/4/2026 | Updated: 5/4/2026 | Inventor(s): Trent Tresch

Keywords(s):

Category(s): Technology Classifications > Engineering & Physical Sciences, Technology Classifications > Engineering & Physical Sciences > Industrial & Manufacturing

Novel co-extrusion module to produce marbled high-moisture composite protein-lipid structures

PRODUCT OPPORTUNITIES Marbled meat alternatives Controlled lipid-protein phase separation PRODUCT OPPORTUNITIES COMPETITIVE ADVANTAGES Controlled phase separation and marbled features In-line co-extrusion module adaptable to current high-moisture extrusion process TECHNOLOGY DESCRIPTION This invention demonstrates...

Published: 5/4/2026 | Updated: 5/4/2026 | Inventor(s): Lutz Grossmann, Carlos Woern, Harris Erdman

Keywords(s):

Category(s): Engineering, Food technology & plant science, Environmental

Enhanced Therapeutic Effect of Armored CAR-T Cells for the Treatment of Glioblastoma (UCLA Case No. 2024-066)

UCLA researchers from the Department of Microbiology, Immunology, and Molecular Genetics have engineered chimeric antigen receptor (CAR)-T cells that co-express defined immunostimulatory cytokines to enhance therapeutic efficiency against glioblastoma (GBM). BACKGROUND: Glioblastoma Multiforme (GBM) is the most common primary malignant brain tumor...

Published: 5/1/2026 | Updated: 5/1/2026 | Inventor(s): Yvonne Chen

Keywords(s):

Category(s): Therapeutics > Oncology, Therapeutics > Immunology And Immunotherapy, Therapeutics > CNS and Neurology

Continuous Kidney and kidney Allograft Monitoring Using a Novel wireless implanted Sensor.

SHORT DESCRIPTION A device to monitor transplanted organs and detect early signs of rejection BACKGROUND End-Stage Renal Disease (ESRD) is a major health and financial problem in the United States. Kidney transplantation is the treatment of choice for ESRD patients, however, the 5-year kidney allograft survival rate is around 72-75%. Rejection...

Published: 5/1/2026 | Updated: 5/1/2026 | Inventor(s):

Keywords(s):

Category(s): Life Sciences > Healthcare Devices, Tools & IT

Microfluidic Lung Chip For Development Modeling

A microfluidic lung chip applies controlled mechanical forces to hydrogel-embedded lung cells or organoids to model lung development in vitro. Problem: Developing lung tissues experiences dynamic mechanical forces during organogenesis. How these forces influence later-stage lung development remains poorly understood. Existing models have not adequately...

Published: 5/4/2026 | Updated: 5/1/2026 | Inventor(s): Dongeun (dan) Huh, Sunghee Estelle Park

Keywords(s): Bioengineering, Pulmonary

Category(s): Technology Classifications > Medical Devices, Technology Classifications > Research Tools & Reagents

Programmable intracellular RNA scaffolds for integrating sensing and regulation

Co-transactionally folded RNA nanostructures in living cells. Invention Summary: Biomarker validation and intracellular RNA detection require tools that are precise, scalable, and capable of capturing complex gene expression patterns. Current approaches, including CRISPR-based systems, RNA interference, and RNA sponge technologies, are often...

Published: 5/1/2026 | Updated: 5/1/2026 | Inventor(s): Fei Zhang, Xu (leo) Chang, Jean-Pierre Etchegaray, Maciej Jeziorek

Keywords(s):

Category(s): Technology Classifications > Healthcare & Life Sciences

Plasma-Enhanced Catalytic Reactor for Selective Methane-to-Methanol Conversion

INVENTORS Dayne Swearer* James Ho * Principal Investigator NU 2024-211 IP STATUS PCT patent application filed DEVELOPMENT STAGE TRL-4 Prototype Validated in Lab: Key functions have been demonstrated in a laboratory-scale prototype. BACKGROUND Methane conversion to methanol is challenging due...

Published: 5/1/2026 | Updated: 5/1/2026 | Inventor(s):

Keywords(s):

Category(s): Physical Sciences > Energy & Sustainability

A Device for Fast and Convenient Assessment of Micro-volume Liquid Dispensing Performance

This technology is a device designed to enable rapid, consistent, and standardized assessment of micro-volume liquid dispensing performance across manual, automated, and robotic workflows. The device provides a controlled and reproducible surface for droplet deposition, incorporating defined features and optional calibration elements that allows for...

Published: 5/1/2026 | Updated: 5/1/2026 | Inventor(s): Chi Zhou

Keywords(s):

Category(s): Technology Classifications > Research Tools, Technology Classifications > Software & Information Technology > Education & Training, Technology Classifications > Creative Works & Copyright, Technology Classifications > Medical Devices

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