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Next-Generation ROS Nanotherapy for Targeted Cancer Destruction

Produces complementary reactive oxygen species in tumors, enabling efficient tumor killing without external activation Background Conventional cancer treatments such as surgery, chemotherapy, and radiotherapy are often invasive, non-specific, and associated with systemic toxicity and long-term side effects. Emerging nanomedicine approaches improve...

Published: 5/8/2026 | Updated: 5/8/2026 | Inventor(s): Oleh Taratula, Olena Taratula, Chao Wang

Keywords(s): breast cancer, chemodynamic therapy (CDT), Fenton reaction, ferrous, immuno-oncology, metal-organic framework (MOF), nanomedicine, oncology therapeutics, porphyrin, reactive oxygen species (ROS), Russell mechanism, solid tumor, tumor microenvironment, tumor suppression, tumor targeting, tumour microenvironment

Category(s): Therapeutics

A Wearable, Waveguide-Integrated Optical System for Measuring Accommodation Changes in the Human Eye

This invention uses a waveguide as an optical combiner to integrate illumination, fixation, and imaging optics into a compact form factor to create a wearable, lightweight optical system for measuring accommodation changes in the human eye. By measuring the relative shift of the extracted beams, the system delivers a direct and highly sensitive way...

Published: 5/7/2026 | Updated: 5/7/2026 | Inventor(s): Hong Hua, Pengyinjie Lyu

Keywords(s):

Category(s): Technology Classifications > Imaging & Optics > Displays, Technology Classifications > Imaging & Optics > Lens & System Design, Technology Classifications > Imaging & Optics > Ophthalmology

A Wearable, Lightguide-Integrated Optical System of Wavefront Sensor for Measuring Aberration in the Human Eye

This invention uses a lightguide as an optical combiner to integrate illumination, fixation, and imaging optics into a single platform and create a wearable, lightweight optical system for measuring optical aberrations in the human eye. By using diffractive or geometric couplers, the invention allows ocular wavefronts to be measured at the same time...

Published: 5/7/2026 | Updated: 5/7/2026 | Inventor(s): Hong Hua, Pengyinjie Lyu

Keywords(s):

Targeted Nanocarriers for Brain Inflammation and Cancer Cachexia

Nanocarriers deliver anti-inflammatory therapeutics across the blood-brain barrier to activated microglia Background Delivering therapeutics to the brain remains a major drug-development challenge because the blood-brain barrier restricts systemic agents from reaching therapeutically relevant concentrations in the central nervous system. This barrier...

Published: 5/7/2026 | Updated: 5/7/2026 | Inventor(s): Oleh Taratula, Olena Taratula, Yoon Tae Goo

Keywords(s): anti-inflammatory, Anti-inflammatory drugs, biodegradable, biodistribution, blood-brain barrier, brain delivery, brain inflammation, CNS drug delivery, cytokine expression, Drug Delivery, Drug Development, glutathione, immune cell, immunohistochemistry, irak4 inhibitor, lipopolysaccharides, microglia, mouse model, nanocarrier, nanocarriers, nanomedicine, neuroinflammation, pancreatic cancer, pharmaceuticals, pharmacokinetics, preservation, pro-inflammatory cytokine, small molecules, water-soluble, weight maintenance

Category(s): Therapeutics

Faster Distributed Systems Using Quasi-Synchrony

A way to organize distributed systems for data centers that require fewer resources and increase efficiency and predictability. Problem: Many distributed systems today are built on the assumption that the system is asynchronous - that packets can be lost or delayed arbitrarily and that clocks are at most weakly synchronized. This assumption results...

Published: 5/7/2026 | Updated: 5/7/2026 | Inventor(s): Andreas Haeberlen, Robert Gifford, Linh Thi Xuan Phan, Qingjie Lu, Karan Newatia

Keywords(s): Data Science, Software

Category(s): Technology Classifications > Computer Information Systems

Targeted Nanoparticle-Mediated HIF Stabilization in Myeloid Cells for Enhanced Transplant Tolerance

SHORT DESCRIPTION A PEG-PPS nanoparticle technology for targeted delivery of roxadustat to myeloid cells to promote transplantation tolerance. INVENTORS Edward Thorp* Northwestern University Feinberg School of Medicine, Department of Pathology Evan Scott* McCormick School of Engineering, Department...