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Deep Learning Model for Continuous ICU Acuity Scoring
Real-time Dynamic Risk Assessments to Improve ICU patient Outcomes and Support Earlier Clinical Interventions This deep learning model provides a continuous acuity score for critically ill patients in the intensive care unit (ICU), enabling earlier clinical interventions and improving patient outcomes. Patients experiencing a medical event may have...
Published: 1/22/2026   |   Inventor(s): Azra Bihorac, Parisa Rashidi, Benjamin Shickel
Keywords(s):  
Category(s): Technology Classifications > Engineering > Computer Science, Technology Classifications > Human Health Care > Diagnostics, Technology Classifications > Software > Healthcare IT
Self-delivery USP10 siRNA to promote regenerative healing-new IP
This technology employs an engineered self-delivering siRNA to selectively reduce USP10 protein levels in tissues, thereby promoting regenerative healing and suppressing pathological scarring. Preclinical studies in the eye demonstrate a favorable safety profile and robust efficacy, supporting the potential of this approach for treating fibrotic disease...
Published: 1/21/2026   |   Inventor(s): Audrey Bernstein, Sean McCauley, Alexey Wolfson, Tere Williams
Keywords(s): fibrosis, opthalmology, scarring, siRNA, skin diseases, Technologies
Category(s): Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Campus > Upstate Medical University
Inhibition of Metastasis in Triple Negative Breast Cancer
This invention uses a therapeutic peptide sequence that inhibits breast cancer metastasis by activating natural killer (NK) cells against breast cancer cells. This inhibitor can be used to treat triple-negative breast cancer metastasis, associated with excess epidermal growth factor receptor (EGRF) which is overexpressed and amplified in 60% of triple-negative...
Published: 1/21/2026   |   Inventor(s): Joyce Schroeder
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Healthcare Portfolios > Women's Health, Technology Classifications > Life Sciences > Therapeutics
Engineered Alphavirus-Like Particles
Application Glyco-engineered virus-like particles (VLPs) to improve vaccine efficacy in eliciting immune responses against viral pathogens by masking off-target epitopes. Key Benefits Enhances immunogenicity to generate high-affinity antibodies against small sub-immunodominant peptides. Improved on-target antibody titers. Minimization of off-target...
Published: 1/20/2026   |   Inventor(s): Rui Kong, Seoho Oh
Keywords(s): Biologics, Immunology and Inflammation Treatments, Immunotherapy, Microbiology and Infectious Disease Treatments, Platform, Preventive Vaccines, Protein and Peptide Therapeutics, Recombinant Vaccines
Category(s): TechPub Algolia > Vaccines
Targeted Candidalysin Binders for Fungal Infection Control
Application A theranostic scaffold-derived protein that neutralizes candidalysin toxin. Key Benefits Different mechanism of action compared to current antifungal drugs, reducing the risk of resistance. Derived from human protein for lower immune response and produced cost-effectively in simple bacterial media. Small size improves tissue penetration...
Published: 1/20/2026   |   Inventor(s): Sohail Khoshnevis, Eric J. Sundberg, Maros Huliciak
Keywords(s): Diagnostics, Drug Discovery, Hydrogels, Protein and Peptide Therapeutics, Therapeutics
Category(s): TechPub Algolia > Therapeutics
A Method for One-Step, Aqueous Phase Generation of Ultrasmall Inorganic Nanoparticles for Biomedical Applications.
A method to generate homogenous and stable inorganic nanoparticles (NPs) using a microfluidic device with two jet inlets. Problem: Inorganic nanoparticles have promise as contrast agents and therapeutics due to their high renal clearance and therefore low toxicity. However, they are limited by factors including complex synthesis routes with unfavorable...
Published: 1/21/2026   |   Inventor(s): David Cormode, Hyun (Michel) Koo, Nil Kanatha Pandey, Andrea Kian, Portia Maidment, Derick Rosario Berrios
Keywords(s): Microfluidics, Platform Technology, Radiology
Category(s): Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Research Tools & Reagents
Reducing Amphotericin B Toxicity via Idebenone Combination
THE CHALLENGE The global burden of invasive fungal infections presents a significant business and healthcare challenge, driven by high morbidity, mortality, and a shrinking pool of effective treatments. The market is constrained by the limited number of antifungal drug classes, with frontline therapies like amphotericin B hindered by severe dose-dependent...
Published: 1/20/2026   |   Inventor(s): Mohamed Seleem, Ehab Salama
Keywords(s):  
Category(s): Technology Classifications > Pharmacology and Therapeutics
Θ-Phase Tantalum Nitride for Thermal Management and Electronics Applications (Case No. 2026-180)
Summary: Researchers in UCLA’s Department of Mechanical and Aerospace Engineering have developed a novel transition metal compound that demonstrates what is thought to be the highest thermal conductivity reported among metallic materials. The material is synthesized as a single, defect-free crystal, enabling unprecedented efficiency in heat transport....
Published: 1/20/2026   |   Inventor(s): Yongjie Hu
Keywords(s): advanced thermal control materials, Composite Material, Electronics & Semiconductors, energy-efficient, heat control, heat controlling devices, heat dissipation, Heat Transfer, high conductivity, material science, Materials, Metals, nanocrystalline metals, Power Electronics, temperature control, thermal control, thermal control materials, thermal management, thermal management systems, thermal metamaterials
Category(s): Chemical, Chemical > Chemical Processing & Manufacturing, Chemical > Synthesis, Electrical, Electrical > Electronics & Semiconductors > Thermoelectrics, Energy & Environment > Thermal, Materials, Materials > Metals, Mechanical > Heat Transfer
iEdison Bulk Upload File Creation Tool
Overview of Software The iEdison Bulk Creation Tool is a proprietary, standalone software application designed to simplify and automate the federal reporting requirements mandated by the Bayh-Dole Act. By serving as an intelligent bridge between raw data collection in Microsoft Excel and the iEdison federal reporting portal, this tool minimizes manual...
Published: 1/16/2026   |   Inventor(s): Andre Kemp
Keywords(s): Software
Category(s): Data Science, Software
Advanced Design Heat Exchanger Formed by Metal Additive Manufacturing
Executive Summary Heat exchangers are common process units used in the chemical, oil and gas, manufacturing and energy sectors. Their efficient design that encompasses efficient heat transfer, low cost and longevity is critical to their success. Researchers at Michigan State University have recently developed a new heat exchanger concept, that uses...
Published: 1/16/2026   |   Inventor(s): James Klausner, Andre Benard, Patrick Kwon, Haseung Chung, Himanshu Sahasrabudhe
Keywords(s):  
Category(s): Advanced Materials, Manufacturing Equipment
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