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Carbon Fiber with Uniform Pore Size
THE CHALLENGE Carbon fibers are used in a wide range of industries and applications including composites, catalysis, sensing, energy conversions and storage and membrane filtration. One approach to make carbon fibers utilizes electrospinning of block copolymers. However, due to challenges associated with the technique, it can be difficult to produce...
Published: 4/9/2025
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Inventor(s):
Guoliang Liu
,
Zhengping Zhou
Keywords(s):
Category(s):
Technology Classifications > Chemicals/Materials
,
Technology Classifications > Engineering
,
Technology Classifications > Energy
,
Technology Classifications > Electronics
Novel Real Time Scheduler
THE CHALLENGE Scheduling bandwidth for multiple cell phone users is presently accomplished almost on an arbitrary basis using a predefined algorithms developed to maximize throughput. Since the scheduling frames are updated every 1 ms, this approach has made it virtually impossible to allocate bandwidth in a real-time, on-demand basis, to achieve best...
Published: 4/9/2025
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Inventor(s):
Yan Huang
,
Yiwei Thomas Hou
,
Yongce Chen
Keywords(s):
Category(s):
Technology Classifications > Communication
Use of 2-Hydroxyoleic Acid for the Treatment of Systemic Lupus Erythematosus and Other Immune Pathologies
A novel B cell tolerance pathway activated by the lipid enzyme sphingomyelin synthases 2 (SMS2). Background: Autoimmune diseases such as Systemic Lupus Erythematosus are chronic, painful and debilitating. The Lupus Foundation of America estimates that 1.5 million Americans, and at least five million people worldwide, have some form of lupus. The...
Published: 4/1/2025
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Inventor(s):
Chongmin Huan
,
Christopher Roman
,
Peiqi Ou
Keywords(s):
TAF
,
Technologies
Category(s):
Campus > SUNY Downstate Health Sciences University
,
Technology Classifications > Therapeutics and Vaccines
Piperlongumine-Based PROTAC As Potent Anticancer Agent With Reduced Toxicity
Uses Piperlongumine as an E3 Ligase Ligand to Facilitate the Degradation of Cancer-Associated Proteins of Interest This naturally occurring compound with anti-cancer properties has the potential to revolutionize cancer treatment by providing tailored therapies with reduced side effects. Cancer remains a significant health issue in the United States,...
Published: 2/26/2025
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Inventor(s):
Guangrong Zheng
,
Daohong Zhou
,
Dongwen Lyu
,
Yaxia Yuan
,
Xingui Liu
,
Yufeng Xiao
,
Wanyi Hu
,
Jing Pei
Keywords(s):
Category(s):
Technology Classifications > Human Health Care > Therapeutics
Cultured Cells Lifting/Cryopreservation Efficiency Training Program
This is an innovative spreadsheet-based method designed to improve the efficiency of training and evaluation for cultured cell lifting and cryopreservation procedures. It is part of a comprehensive training program aimed at streamlining skill acquisition in cell culture labs. Unlike traditional methods, where training outcomes are evaluated broadly...
Published: 1/21/2025
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Inventor(s):
Chi Zhou
Keywords(s):
Category(s):
Technology Classifications > Research Tools > Cell Lines
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Technology Classifications > Software & Information Technology > Education & Training
Identification of NFAT5 as a novel target for preventing KRAS targeted therapy resistance
Inhibiting NFAT5 attenuates pancreatitis-induced resistance to KRAS inhibition and extends mouse survival. Invention Summary: Resistance to KRAS targeted therapy in cancers involves epithelial-to-mesenchymal transition (EMT), which poses challenges for effective targeting. However, the mechanism underlying EMT associated KRAS resistance...
Published: 1/6/2025
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Inventor(s):
Pingping Hou
,
Daiyong Deng
Keywords(s):
Anti-cancer
Category(s):
Technology Classifications > Cancer
,
Technology Classifications > Healthcare & Life Sciences
,
Technology Classifications > Therapeutics
Chip-integrated Nanolaminate Nano-optoelectrode Arrays for Interfacial Electrochemical Reaction Monitoring
THE CHALLENGE: In the field of electrochemistry, understanding the dynamics of interfacial reactions is crucial for advancements in areas such as electrocatalysis, biosensing, and energy conversion. Real-time monitoring of these reactions allows scientists to gain insights into mechanisms that drive these processes. Accurate and detailed analysis of...
Published: 4/2/2025
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Inventor(s):
Yuming Zhao
,
Chuan Xiao
,
Wei Zhou
Keywords(s):
Category(s):
Technology Classifications > Chemicals/Materials
Battery-Free Wireless Epidermal Sensor Networks for Continuous and High-Fidelity Systolic Blood Pressure Monitoring
This invention is a wireless, battery-free system of epidermal sensors designed for continuous and high fidelity monitoring of physiological signals, such as blood pressure. The system eliminates the need for batteries by using a smartphone to wirelessly deliver power to the sensors and collect biosignals. The sensors are designed to function seamlessly...
Published: 12/17/2024
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Inventor(s):
Philipp Gutruf
,
Kevin Kasper
,
Selman Kurt
,
S. Y. John Ho
Keywords(s):
Category(s):
Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation
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Technology Classifications > Engineering & Physical Sciences > Communications & Networking > Wireless
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Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary
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Technology Classifications > Sensors & Controls
Enzymatic Reactions for Modifying and Labeling Extracellular Vesicles
Applies Enzymatic Glycan Engineering to Functionalize and Tag Extracellular Vesicles This method for modifying extracellular vesicles combines enzymatic glycan engineering with chemoselective functionalization to unlock applications such as targeted drug delivery. Extracellular vesicles are lipid bilayer-enclosed nanoparticles secreted by cells, acting...
Published: 3/27/2025
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Inventor(s):
Zhongwu Guo
,
Mohit Jaiswal
,
Yong Zeng
,
Xin Zhou
,
Jiatong Guo
Keywords(s):
Category(s):
Technology Classifications > Engineering > Chemical
,
Technology Classifications > Human Health Care > Diagnostics
Specialized storage technology for preserving axonal viability
A specialized calcium-free solution preserves peripheral nerve axons for up to nine days at low temperatures, enhancing nerve graft viability for effective repair of injuries using polyethylene glycol fusion, promoting rapid sensory and motor recovery. Background Peripheral nerve injuries (PNIs) often result in segmental-loss defects, leading to immediate...
Published: 10/21/2024
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Inventor(s):
George Bittner
,
David Jackson
,
Alexa Olivarez
,
Liwen Zhou
,
Cathy Yang
Keywords(s):
Category(s):
Life sciences > Therapeutics > Formulation
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