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SPLICER: Small Molecule-Inducible Gene Expression Switches
Enables Ligand-Inducible Regulation of Gene Expression or Knockdown This small molecule-inducible gene expression based on riboswitches (SPLICER) enables precise, drug-responsive control of gene expression for safer and more flexible gene and cell therapies. In mammalian cells, alternative splicing greatly expands the diversity of RNA sequences. These...
Published: 9/2/2025
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Inventor(s):
Eric Wang
,
Yu Zhou
Keywords(s):
Category(s):
Technology Classifications > Human Health Care > Therapeutics
,
Technology Classifications > Research Tools > Therapeutics
One-Pot Wonder. Precision-Crafted Nanocrystals, The Power of Platinum Without the Price.
Title: One-Pot Wonder. Precision-Crafted Nanocrystals, The Power of Platinum Without the Price. This invention introduces a one-pot synthesis of Mn-based spinel nanocrystals with {101} facets, delivering high ORR efficiency and durability as a cost-effective, non-platinum catalyst for fuel cells. Background: Platinum-based catalysts dominate proton...
Published: 9/3/2025
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Inventor(s):
Jiye Fang
,
Ming Zhou
Keywords(s):
Technologies
Category(s):
Campus > Binghamton University
Beam-controlled Spectral-selective Architecture for a Radiative Cooler
This invention enhances radiative cooling of buildings by manipulating the divergent angle of thermal emission. By adjusting the direction at which heat is diverted away from buildings by this beam controlled design, the dependence of radiative cooling performance on the presence of surrounding architecture and environment can be minimized. US12352...
Published: 9/12/2025
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Inventor(s):
Qiaoqiang Gan
,
Lyu Zhou
,
Zongfu Yu
,
Haomin Song
Keywords(s):
Category(s):
Technology Classifications > Energy Conservation
Soft inflatable robot for in-pipe inspection
Background Pipeline infrastructure in oil and gas, water systems, and chemical processing requires regular internal inspections to detect corrosion, blockages, and structural damage. However, many pipelines are narrow, tortuous, and operate under variable pressure and flow conditions, making access with conventional tools difficult. Rigid robotic crawlers...
Published: 8/14/2025
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Inventor(s):
Farshid Alambeigi
,
Linh Nguyen
,
Van Ho
Keywords(s):
Category(s):
Life sciences > Diagnostic
,
Life sciences > Medical technology > Medical devices
A Real-time Interference Mitigation Method for Automotive Radar
THE CHALLENGE The growing adoption of FMCW radar in modern vehicles—used for crucial functions like collision avoidance and autonomous driving faces a serious business and technical challenge: mutual radar interference. As more vehicles hit the road with similar radar systems, their signals often overlap, creating "noise" that hides...
Published: 8/14/2025
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Inventor(s):
Yubo Wu
,
Yiwei Thomas Hou
Keywords(s):
Category(s):
Technology Classifications > Transportation
Large-Area Solution-Processed Ionomer-Interlayered Bulk Monolayer MOS2 Membranes With Thickness-Scalable Bright Luminescence and Dual Electron-Ion Transport (Case No. 2025-281)
Summary: UCLA researchers have developed a novel hybrid 2D material platform that significantly improves the utility and optical performance of monolayer molybdenum disulfide (MoS2) by integrating a Nafion interlayer. Background: Monolayer transition metal dichalcogenides (TMDs), particularly MoS2, have shown promise in the fields of optics and...
Published: 8/7/2025
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Inventor(s):
Xiangfeng Duan
,
Yu Huang
,
Boxuan Zhou
Keywords(s):
Category(s):
Materials
,
Materials > Functional Materials
,
Materials > Semiconducting Materials
,
Materials > Membranes
,
Materials > Composite Materials
,
Electrical
,
Electrical > Flexible Electronics
,
Electrical > Electronics & Semiconductors
,
Electrical > Sensors
,
Chemical
,
Chemical > Chemical Sensors
,
Chemical > Polymers
Biocompatible photoenzymatic system for selective C–H fluorination
Background C–H fluorination plays a central role in pharmaceutical and agrochemical synthesis, as the introduction of fluorine often enhances a molecule's metabolic stability, potency, and bioavailability. Over 20% of approved drugs contain fluorinated functional groups, underscoring the demand for efficient and selective fluorination methods....
Published: 7/31/2025
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Inventor(s):
Yi Lu
,
Yu Zhou
Keywords(s):
Category(s):
Life sciences > Metabolic engineering
OPG153-based vaccine for targeted mpox immunization
Background The global re-emergence of monkeypox virus (MPXV) has created a critical need for effective and well-tolerated vaccines to prevent infection, limit disease severity, and reduce transmission. As an orthopoxvirus related to smallpox, mpox presents a unique public health challenge, especially for immunocompromised populations. Current...
Published: 7/31/2025
|
Inventor(s):
Jason McLellan
,
Ling Zhou
,
Emily Rundlet
,
Emanuele Andreano
,
Rino Rappuoli
,
Ida Paciello
,
Giulia Realini
,
Federica Perrone
Keywords(s):
Category(s):
Life sciences > Therapeutics > Vaccines
A General Cation-Exchange Approach to Magnetic Intercalation Superlattices (Case No. 2025-9A1)
Summary: UCLA researchers in the Department of Chemistry have developed a general cation-exchange approach for tunable magnetic intercalation superlattices. Background: Layered materials are crucial for engineering quantum and magnetic phenomena at the atomic scale. Magnetic intercalation superlattices, a type of layered materials, enable tunable...
Published: 7/24/2025
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Inventor(s):
Xiangfeng Duan
,
Yu Huang
,
Jingxuan Zhou
Keywords(s):
Advanced Computing / AI
,
advanced packaging
,
Cation exchange
,
doping control
,
Fabrication Technologies
,
ferromagnetic semiconductor
,
layered materials
,
magnetic coupling
,
magnetic intercalation superlattices
,
quantum communication
,
Quantum Computer
,
quantum computing materials
,
Quantum Dot
,
quantum error correction (QEC)
,
quantum incompressible fluid
,
quantum key
,
quantum network
,
quantum processing
,
quantum processor
,
room-temperature superconductivity
,
spin textures
,
spintronics
,
trapped ion quantum processor
,
tunable ferromagnetism
,
Van der Waals
,
Van Der Waals Force
,
VIN group metals
Category(s):
Materials
,
Materials > Nanotechnology
,
Materials > Functional Materials
,
Materials > Semiconducting Materials
,
Materials > Fabrication Technologies
,
Materials > Metals
,
Optics & Photonics
Multi-List Strategy for Spectrum Interference Management
THE CHALLENGE Spectrum managers operating in shared-spectrum environments (e.g., the CBRS band) face a critical challenge: protecting high-priority incumbents such as Navy radar while maintaining reliable service for commercial users. Static move lists—the prevailing industry approach—repeatedly shut down the same base stations during...
Published: 7/16/2025
|
Inventor(s):
Naru Jai
,
Yubo Wu
,
Yi Shi
,
Yiwei Thomas Hou
Keywords(s):
Category(s):
Technology Classifications > Communication
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