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Methods To Regulate Metabolism For Treatment Of Neural Injuries and Neurodegeneration
Description of Technology: Axonal injury and subsequent neuronal death underpin the pathology of many neurological disorders from acute neural injuries (motor vehicle crashes, combat related injuries, traumatic brain injuries) to neurological diseases (multiple sclerosis, glaucoma). In the central nervous system (CNS), microglia help respond to CNS...
Published: 4/16/2026   |   Updated: 4/16/2026   |   Inventor(s): Wei Li, Jingxing Ou, Tantai Zhao
Keywords(s):  
Category(s): Application > Therapeutics, Collaboration Sought > Collaboration, TherapeuticArea > Ear, Nose, & Throat, TherapeuticArea > Neurology, Collaboration Sought > Licensing
48-Position Custom Deep Well Plate For In Vitro Equilibrium Dialysis at a 1:1 Sample to Buffer Volume Ratio
CDC scientists have developed a new design for a multi-well dialysis microplate for equilibrium dialysis. The unique design accommodates a 1:1 buffer to sample ratio and provides additional room at the base of the well to enable optimal cartridge immersion and analyte diffusion. The microplate is readily adaptable into existing automated analytical...
Published: 4/10/2026   |   Updated: 4/8/2026   |   Inventor(s): Ashley Ribera, Hui Zhou, Hubert Vesper
Keywords(s):  
Category(s): Application > Diagnostics, Application > Research Materials, Collaboration Sought, TherapeuticArea, TherapeuticArea > Endocrinology, TherapeuticArea > Geriatrics, TherapeuticArea > Hematology, TherapeuticArea > Obstetrics/Neo-Natal, TherapeuticArea > Reproductive Health, TherapeuticArea > Urology
A Method to Accelerate Federated Learning via Client Hopping
THE CHALLENGE Organizations across healthcare, finance, manufacturing, and edge computing increasingly look to federated learning to extract value from sensitive, distributed data while maintaining privacy and regulatory compliance. Yet scaling this technology into a reliable commercial solution remains challenging, as current architectures struggle...
Published: 3/24/2026   |   Updated: 3/24/2026   |   Inventor(s): Fangtong Zhou, Yi Shi, Yiwei Thomas Hou
Keywords(s):  
Category(s): Technology Classifications > Computer Science
A Method to Accelerate Federated Learning via Client Hopping
THE CHALLENGE Organizations across healthcare, finance, manufacturing, and edge computing increasingly look to federated learning to extract value from sensitive, distributed data while maintaining privacy and regulatory compliance. Yet scaling this technology into a reliable commercial solution remains challenging, as current architectures struggle...
Published: 3/24/2026   |   Updated: 3/24/2026   |   Inventor(s): Fangtong Zhou, Yi Shi, Yiwei Thomas Hou
Keywords(s):  
Category(s): Technology Classifications > Computer Science
Apelin-Receptor (APJ) Antagonists
A series of stable, small molecule compounds that inhibit an alternative (non-VEGF) angiogenic pathway that is overexpressed in a variety of cancers. Background: Antiangiogenic drugs targeting the vascular endothelial growth factor (VEGF) signaling pathway are widely used to treat solid tumors and ocular conditions such as wet AMD. However, anti-VEGF...
Published: 4/16/2026   |   Updated: 3/23/2026   |   Inventor(s): Youngjae You, Sukyung Woo, Ganesh Bist, Ahmed Elsheikh
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Drug Design and Synthesis
Beamforming Device and Architectures for Large Language Model Enabled Personal Monitoring
WisperWatcher is a wearable audio-based system that automatically monitors eating behavior by capturing and analyzing mastication and swallowing sounds. Leveraging beamforming techniques combined with Large Audio-Language Models (LALM), it provides accurate, real-time insights into food intake, meal timing, and user disposition while minimizing user...
Published: 4/16/2026   |   Updated: 3/17/2026   |   Inventor(s): Alexander Gherardi, Wenyao Xu, Wei Bo, Shuwei Hou
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Artificial Intelligence, Technology Classifications > Medical Devices
Printing Nanoporous Ultrathin Membranes for Lithium-Sulfur Batteries
RPI ID: 2019-021-401 Innovation Summary: This technology provides a graphene oxide (GO) printed coating for separator membranes in lithium-sulfur (Li–S) batteries. The printed GO layers block polysulfide migration, addressing the ‘shuttle effect’ that reduces Coulombic efficiency and cycle life. Unlike traditional coatings,...
Published: 3/10/2026   |   Updated: 3/10/2026   |   Inventor(s): Miao Yu, Fanglei Zhou, Feng Zhao, Jinyun Liao
Keywords(s): Li-S battery, Lithium-Sulfur, Membranes, polysulfide blocking, Rechargeable batteries, ultrathin functional coatings
Category(s): Energy, Environment and Smart Systems
Manipulation of Gaseous Ion Beams with Acoustic Fields
RPI ID: 2023-084-301 Innovation Summary: This technology enables precise control of gaseous ion beams using acoustic fields. The system manipulates ions in a gas phase by applying acoustic waves to direct, focus, or modulate their trajectories. It enhances ion beam steering without relying on traditional electromagnetic methods. The approach is compatible...
Published: 3/10/2026   |   Updated: 3/10/2026   |   Inventor(s): Yi You, Jens Riedel, Julia Danischewski, Jacob Shelley
Keywords(s): ion deposition, ion mobility spectrometry, ion movement, ion separation, Mass Spectrometry, materials development, materials processing
Category(s): Energy, Environment and Smart Systems
Small-Molecule IL-6 Inhibitors Targeting gp130 for Anti-Cancer Therapy
Blocks IL-6-gp130 Signaling for Cost-Effective Treatment of Autoimmune Diseases and IL-6–Driven Cancers These small-molecule interleukin-6 (IL-6) inhibitors target glycoprotein 130 (gp130) by blocking IL-6-gp130 signaling, delivering a cost-effective therapy for autoimmune diseases and IL-6-driven cancers. IL-6-gp130 signaling drives tumor growth...
Published: 3/31/2026   |   Updated: 3/2/2026   |   Inventor(s): Chenglong Li, Liguang Mao, Daniel Schultz, Zhihang Shen, Xiaozhi Yang, Wei Zhou
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Therapeutics
A low-cost indoor positioning system for robotics research and education
Reference #: 1705 The University of South Carolina is offering licensing opportunities for A low-cost indoor positioning system for robotics research and education. Background: Mobile robots are widely used in robotics research, education, and competition. Many applications require accurate, real-time knowledge of a robot’s position to support...
Published: 2/11/2026   |   Updated: 2/11/2026   |   Inventor(s): Yi Wang, Junlin Ou
Keywords(s):  
Category(s): Engineering and Physical Sciences
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