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Process and method for novel biomarker discovery using electromagnetic beta signal waveforms for prediction and diagnosis of neurological disorders and brain states
Dissecting beta waveforms using convolutional dictionary learning across sensory perception, aging, and disease OVERVIEW This technology is a system and method for analyzing brain wave patterns, specifically beta waves (13-30 Hz), to identify biomarkers that can predict neurological conditions and brain states. The technology leverages advanced signal...
Published: 5/22/2025
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Inventor(s):
Stephanie Jones
,
David Zhou
Keywords(s):
Category(s):
Aging
,
Neurodegenerative Disease
,
Neuroscience
Use of 2-Hydroxyoleic Acid for the Treatment of Systemic Lupus Erythematosus and Other Immune Pathologies
A novel B cell tolerance pathway activated by the lipid enzyme sphingomyelin synthases 2 (SMS2). Background: Autoimmune diseases such as Systemic Lupus Erythematosus are chronic, painful and debilitating. The Lupus Foundation of America estimates that 1.5 million Americans, and at least five million people worldwide, have some form of lupus. The...
Published: 5/13/2025
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Inventor(s):
Chongmin Huan
,
Christopher Roman
,
Peiqi Ou
Keywords(s):
TAF
,
Technologies
Category(s):
Campus > SUNY Downstate Health Sciences University
,
Technology Classifications > Therapeutics and Vaccines
RNA Purification with DNA Nanoswitches
Novel, user-centric technology for detecting and analyzing RNA that accelerates the pace of discovery in RNA research. Background: RNA purification is an important part of biomedical research, and very few tools exist for pulling specific RNAs out of a complex solution. Further, understanding of RNA and its complex roles in biology is constantly evolving....
Published: 5/13/2025
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Inventor(s):
Kenneth Halvorsen
,
Lifeng Zhou
Keywords(s):
Category(s):
Campus > University at Albany
,
Technology Classifications > Diagnostics
,
Technology Classifications > Research Tools and Reagents
Portable Assay for COVID-19 Diagnostic
A low-cost, rapid, and more accurate gel electrophoresis-based assay using DNA nanoswitches for detecting COVID-19 and other viruses. Background: Viral diagnostics are of prime importance for testing infection rates and for timely treatment, especially in the case of a pandemic such as the current COVID-19 outbreak caused by the SARS-CoV-2 corona...
Published: 5/13/2025
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Inventor(s):
Kenneth Halvorsen
,
Lifeng Zhou
Keywords(s):
DNA
,
RNA
,
Technologies
Category(s):
Campus > University at Albany
,
Technology Classifications > Diagnostics
Washable SERS Fabrics via Micro-Imprinting
THE CHALLENGE The major challenge in wearable SERS (Surface-Enhanced Raman Spectroscopy) sensors lies in bridging the gap between cutting-edge lab technology and real-world usability. While SERS offers powerful, label-free chemical detection at the molecular level, current fabrication methods rely on expensive clean-room processes, rigid substrates,...
Published: 5/9/2025
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Inventor(s):
Aditya Garg
,
Wei Zhou
Keywords(s):
Category(s):
Technology Classifications > Engineering
,
Technology Classifications > Biomedical
Fast Viral Detection via SERS and Machine Learning
THE CHALLENGE The key challenge in developing effective virus detection tools for real-world environments lies in bridging the gap between laboratory-grade accuracy and field-ready usability. Current diagnostic methods like PCR and immunoassay are highly sensitive but depend on complex sample preparation, costly reagents, cold-chain logistics, and...
Published: 5/5/2025
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Inventor(s):
Aditya Garg
,
Wei Zhou
,
Peter Vikesland
,
Linsey Marr
,
Nisha Duggal
Keywords(s):
Category(s):
Technology Classifications > Biomedical
,
Technology Classifications > Engineering
Custom AI Co-Pilot for Software Security Pen-Testing
Advantages: Helps scale pen-testing efforts by assisting human testers with AI Learns from each test and gets better over time Built to match real-world workflows using open-source tools and prompts Outperforms traditional tools like SonarQube with prompt customization Summary: Penetration testing is critical for finding security flaws in software....
Published: 4/18/2025
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Inventor(s):
Xinming (Simon) Ou
,
Dmitry Goldgof
,
Jarred Ligatti
,
Lawrence Hall
Keywords(s):
Artificial Intelligence
,
Cybersecurity
Category(s):
Technology Classifications > Data/AI > Cybersecurity - Data/AI
Carbon Fiber with Uniform Pore Size
THE CHALLENGE Carbon fibers are used in a wide range of industries and applications including composites, catalysis, sensing, energy conversions and storage and membrane filtration. One approach to make carbon fibers utilizes electrospinning of block copolymers. However, due to challenges associated with the technique, it can be difficult to produce...
Published: 4/9/2025
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Inventor(s):
Guoliang Liu
,
Zhengping Zhou
Keywords(s):
Category(s):
Technology Classifications > Chemicals/Materials
,
Technology Classifications > Engineering
,
Technology Classifications > Energy
,
Technology Classifications > Electronics
Novel Real Time Scheduler
THE CHALLENGE Scheduling bandwidth for multiple cell phone users is presently accomplished almost on an arbitrary basis using a predefined algorithms developed to maximize throughput. Since the scheduling frames are updated every 1 ms, this approach has made it virtually impossible to allocate bandwidth in a real-time, on-demand basis, to achieve best...
Published: 4/9/2025
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Inventor(s):
Yan Huang
,
Yiwei Thomas Hou
,
Yongce Chen
Keywords(s):
Category(s):
Technology Classifications > Communication
Piperlongumine-Based PROTAC As Potent Anticancer Agent With Reduced Toxicity
Uses Piperlongumine as an E3 Ligase Ligand to Facilitate the Degradation of Cancer-Associated Proteins of Interest This naturally occurring compound with anti-cancer properties has the potential to revolutionize cancer treatment by providing tailored therapies with reduced side effects. Cancer remains a significant health issue in the United States,...
Published: 5/30/2025
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Inventor(s):
Guangrong Zheng
,
Daohong Zhou
,
Dongwen Lyu
,
Yaxia Yuan
,
Xingui Liu
,
Yufeng Xiao
,
Wanyi Hu
,
Jing Pei
Keywords(s):
Category(s):
Technology Classifications > Human Health Care > Therapeutics
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