Search Results - yiming+xiao

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A novel virtual-reality system for planning deep brain stimulation surgery
A Virtual-Reality System for Planning Deep Brain Stimulation Surgery Eye-tracking capabilities to safely find your path across the neurons Credit Shutterstock : 1243953517 UNMET NEED Deep Brain Stimulation (DBS) is a neurosurgical procedure in which electrodes are implanted into the brain to send electrical signals to specific deep areas...
Published: 6/13/2025   |   Inventor(s): Owen Hellum, Yiming Xiao
Keywords(s): Innovation
Category(s): Objectifs de Développement Durable > ODD 03 : Bonne santé et bien-être, Secteurs > Sciences de la vie, Sectors > Life sciences, Applications > Soins et santé > Traitement > Dispositifs médicaux, English Applications > Health and care > Treatment > Medical devices-T, Sustainable Development Goals > Goal 03: Good Health and Well-Being
Telomere assay for the detection of alternative lengthening of telomere (ALT) activity in cells
PAGE TITLE Overview PAGE SUMMARY Executive Statement: A unique tool for distinguishing cancer cells based on telomere maintenance mechanisms, providing potential biomarkers for cancer subtypes and therapeutic responses. Description: This technology provides detailed telomere profiling from individual chromosomes, capable of differentiating...
Published: 2/19/2025   |   Inventor(s): Ming Xiao
Keywords(s):  
Category(s): Medical Devices, Diagnostics & Biosensors
Quantification of On-off target gene editing by optical mapping
PAGE TITLE Overview PAGE SUMMARY Executive Statement: A revolutionary methodology for quantifying on-target and off-target gene editing activity using CRISPR-Cas9 and optical mapping. Description: This technology comprises a single-molecule optical mapping strategy using CRISPR-Cas9 to fluorescently label the modified genes. The method involves...
Published: 2/19/2025   |   Inventor(s): Ming Xiao, Yilin Wang, Lahari Uppuluri
Keywords(s):  
Category(s): Medical Devices, Diagnostics & Biosensors
Multicolor whole-genome mapping for genetic analysis
PAGE TITLE Overview PAGE SUMMARY Executive Statement: A novel method for precise genome mapping and sequencing using Cas9-mediated labeling within nanochannels. Description: This technology is a method for mapping a whole genome using a universal multi-color mapping strategy in nanochannels that combines a conventional sequence-motif labeling...
Published: 4/11/2025   |   Inventor(s): Ming Xiao, Lahari Uppuluri
Keywords(s):  
Category(s): Medical Devices, Diagnostics & Biosensors
Linked-read sequencing library preparation
PAGE TITLE Overview PAGE SUMMARY Executive Statement: Innovative methods for generating sequence-linked DNA fragments for high-quality, low-cost genome sequencing. Description: This technology describes a novel strategy to construct a long-read sequencing library such that adjacent fragments are linked with end-terminal duplications. The...
Published: 2/19/2025   |   Inventor(s): Ming Xiao, Lahari Uppuluri
Keywords(s):  
Category(s): Medical Devices, Diagnostics & Biosensors
Single molecule real-time long DNA mapping and sequencing
PAGE TITLE Overview PAGE SUMMARY Executive Statement: The invention offers an innovative way to immobilize and optically map/sequence oligonucleotides on a micropatterned substrate for efficient large-scale genomic assembly. Description: This technology presents a method for immobilizing and linearizing oligonucleotides on a micropatterned...
Published: 2/19/2025   |   Inventor(s): Ming Xiao, Dharma Varapula, Eric LaBouff, Moses (hongseok) Noh
Keywords(s):  
Category(s): Medical Devices, Diagnostics & Biosensors
CRISPR-Cas9 Labeling of Human Genomic DNA for Telomere Length Measurement
PAGE TITLE Overview PAGE SUMMARY Executive Statement: An innovative method for the precise detection and measurement of individual telomere lengths that can be correlated to specific chromosomes. Description: This technology provides a method for detecting the length of individual telomeres in genomic DNA using a unique combination of guide...
Published: 2/19/2025   |   Inventor(s): Ming Xiao, Jennifer McCaffrey
Keywords(s):  
Category(s): Medical Devices, Diagnostics & Biosensors
Methods of specifically labeling nucleic acids using CRISPR/Cas9
se; } PAGE TITLE Overview PAGE SUMMARY Executive Statement: A new genome analysis technique that uses guide RNA and Cas9 nickase to detect target nucleic acid sequences using fluorescent labeling. Description: The technology involves a method for sequence-specific labeling that can target repetitive regions in the genome. This method contacts...
Published: 2/19/2025   |   Inventor(s): Ming Xiao, Jennifer McCaffrey, Harold Riethman, Wenhui Hu
Keywords(s):  
Category(s): Medical Devices, Diagnostics & Biosensors
Whole genome mapping by DNA sequencing with linked paired-end library
se; } PAGE TITLE Overview PAGE SUMMARY Executive Statement: A novel and highly efficient method of sequencing and mapping the whole genome, promising increased accuracy and lower costs. Description: This technology addresses challenges in genomics like accurate de novo genome assembly and structural variant analysis. It proposes a more efficient...
Published: 2/19/2025   |   Inventor(s): Ming Xiao, Justin Sibert
Keywords(s):  
Category(s): Medical Devices, Diagnostics & Biosensors
Electrohydrodynamic Patterning of Colloidal Crystals
Researchers at Princeton University have developed a new method of producing materials with micron and submicron patterns. Such materials are important in numerous applications, including photonic materials, high-density magnetic data storage devices, microchip reactors, and biosensors. Princeton is currently seeking industrial collaborators...
Published: 7/9/2024   |   Inventor(s): Ilhan Aksay, Dudley Saville, Deceased, Yi Xiao, Hak Poon, Ryan Hayward
Keywords(s):  
Category(s): Materials