Search Results - lahari+uppuluri

5 Results Sort By:
Quantification of On-off target gene editing by optical mapping
PAGE TITLE Overview PAGE SUMMARY Executive Statement: A revolutionary methodology for quantifying on-target and off-target gene editing activity using CRISPR-Cas9 and optical mapping. Description: This technology comprises a single-molecule optical mapping strategy using CRISPR-Cas9 to fluorescently label the modified genes. The method involves...
Published: 6/28/2024   |   Inventor(s): Ming Xiao, Yilin Wang, Lahari Uppuluri
Keywords(s):  
Category(s): Life Sciences, Medical Devices & Diagnostics, Medical Devices & Diagnostics > MDD: Diagnostic Tests, Research Tools & Materials, Pharmaceuticals & Therapeutics > Pharma: Cellular Therapy, Pharmaceuticals & Therapeutics > Pharma: Gene Therapy, Pharmaceuticals & Therapeutics > Pharma: Genome Engineering
Multicolor whole-genome mapping for genetic analysis
PAGE TITLE Overview PAGE SUMMARY Executive Statement: A novel method for precise genome mapping and sequencing using Cas9-mediated labeling within nanochannels. Description: This technology is a method for mapping a whole genome using a universal multi-color mapping strategy in nanochannels that combines a conventional sequence-motif labeling...
Published: 6/20/2024   |   Inventor(s): Ming Xiao, Lahari Uppuluri
Keywords(s):  
Category(s): Life Sciences, Medical Devices & Diagnostics, Medical Devices & Diagnostics > MDD: Diagnostic Tests, Pharmaceuticals & Therapeutics > Pharma: Cellular Therapy, Pharmaceuticals & Therapeutics > Pharma: Gene Therapy, Pharmaceuticals & Therapeutics > Pharma: Genome Engineering, Research Tools & Materials
Linked-read sequencing library preparation
PAGE TITLE Overview PAGE SUMMARY Executive Statement: Innovative methods for generating sequence-linked DNA fragments for high-quality, low-cost genome sequencing. Description: This technology describes a novel strategy to construct a long-read sequencing library such that adjacent fragments are linked with end-terminal duplications. The...
Published: 6/28/2024   |   Inventor(s): Ming Xiao, Lahari Uppuluri
Keywords(s):  
Category(s): Life Sciences, Medical Devices & Diagnostics > MDD: Diagnostic Tests, Pharmaceuticals & Therapeutics > Pharma: Genome Engineering, Pharmaceuticals & Therapeutics > Pharma: Gene Therapy, Pharmaceuticals & Therapeutics > Pharma: Cellular Therapy, Research Tools & Materials
y-AApeptide-based long-acting pan-coronavirus fusion inhibitor with dual targets in spike protein and oral bioavailability
­Advantages: S-20-1 demonstrates potent inhibitory action, this broad-spectrum activity suggests that S-20-1 could be effective against a wide range of coronaviruses, making it a valuable candidate for pandemic preparedness and management. The research provides insights into the mechanism of action of S-20-1, demonstrating its ability to bind...
Published: 9/25/2023   |   Inventor(s): Jianfeng Cai, Shibo JIANG, Lu LU, Songyi XUE, Xinling WANG, Lei WANG, Wei XU, Shuai XIA
Keywords(s): Drug Discovery, Immunology
Category(s): Technology Classifications > Medical > Biotechnology
Network-Coded Multiple Access
[Licensing negotiation in progress] [Invitation for Expression of Interest - Deadline: 16 June 2016] Systems and methods include a first wireless local area network (WLAN) system that jointly exploit physical-layer network coding (PNC) and multi-user decoding (MUD) to boost system throughput. This multiple access mode is referred to as Network-Coded...
Published: 1/29/2024   |   Inventor(s): Soung Chang Liew, Lu LU, Lizhao You
Keywords(s): Network Coding, Wireless Local Area Network
Category(s): Information and Communications Technology