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Antibiotic Drug Eluting Patches for Treatment of Ocular Inflammation (UCLA Case No. 2022-157)
UCLA researchers in the Department of Chemical and Biomolecular Engineering have developed an antibiotic drug eluting patch to treat eye diseases, including ocular infection and inflammation. It offers sustained drug delivery to enhance biocompatibility and antimicrobial effectiveness, and provides a localized, noninvasive, and patient-compliant method...
Published: 10/24/2025   |   Inventor(s): Nasim Annabi, Shima Gholizadeh, Yangcheng Liu
Keywords(s):  
Category(s): Therapeutics > Ophthalmology, Chemical > Polymers, Materials > Nanotechnology
Rechargeable battery electrolytes for extreme cycling conditions
Background As the world increasingly relies on portable electronics, electric vehicles, and renewable energy storage, the demand for high-performance, reliable, and durable rechargeable batteries continues to grow. However, current lithium-ion batteries (LIBs) face significant challenges under extreme operating condi­tions, such as subzero temperatures,...
Published: 10/6/2025   |   Inventor(s): Arumugam Manthiram, Zehao Cui, Chen Liu
Keywords(s):  
Category(s): Physical sciences > Energy > Battery or electrochemical
Multi-parametric Acoustic, Optical and Mechanical Imaging of Cervical Tissue Insufficiencies to Predict Preterm Birth
An enhanced image-guidance system that integrates ultrasound and photoacoustic into existing ablation systems to provide an enhanced image-guidance system for identification of cervical tissue changes during pregnancy and postpartum. Technology Summary Preterm delivery is a main cause of perinatal morbidity and mortality worldwide, which is associated...
Published: 10/1/2025   |   Inventor(s): Mohammad Mehrmohammadi, Sonia Hassan, Edgar Hernandez-Andrade, Yan Yan, Maryam Basij
Keywords(s): Driving Lifelong Health
Category(s): Technology Category > Women's Health, Technology Category > Medical Devices, Technology Category > Life Science, Technology Category > Imaging, Technology Category > Acoustics
M4 Foldamer Peptidomimetic: Targeting Amyloid-beta (Aβ) Aggregation to Restore Neuronal Function in Alzheimer’s Disease
Adantages Enhanced Blood-Brain Barrier (BBB) Penetration allows for efficient therapeutic targeting Superior serum stability enables a longer therapeutic window compared to conventional peptide therapeutics Multimodal therapeutic mechanism simultaneously addresses multiple pathological hallmarks of Alzheimer’s Disease (AD) Summary Alzheimer’s...
Published: 10/16/2025   |   Inventor(s): Jianfeng Cai, Heng Liu, Donghui Zhu, Firoz Akhter
Keywords(s): Alzheimer's Disease, Neurodegenerative Diseases, Therapeutics
Category(s): zzNeurodegenerative Diseases Treatment, Technology Classifications > Medical > Neuroscience, Technology Classifications > Medical > Therapeutics
Sensitive Point-of-Care miRNA Detection Using a One-Pot, Isothermal Assay
Rapid, RNA Extraction-Free Detection of miRNAs Biomarkers for Accurate Cancer Diagnosis and Prognosis This CRISPR-Cas12a-based assay allows for the rapid, sensitive detection of microRNAs using a one-pot, isothermal process. MicroRNAs(miRNAs) are endogenous and short, non-coding single-stranded RNAs. They participate in various biological functions...
Published: 5/30/2025   |   Inventor(s): Yong Zeng, He Yan
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Diagnostics, Technology Classifications > Veterinary > Diagnostics
Steric Hindrance Effect of Additives for Tuning the Perovskite Crystal Orientation (Case No. 2024-023)
Summary: UCLA Researchers in the Department of Materials Science and Engineering have developed a method to tune perovskite crystal orientation for increased performance, energy efficiency, and reduced material defect with a variety of field applications, including solar cells and LEDs. Background: Perovskite holds considerable promise as a highly...
Published: 2/14/2025   |   Inventor(s): Yang Yang, Chunqing Ma, Haoxiang Duan, Dong Meng
Keywords(s): Energy Efficiency, energy-efficient, Imaging, Liquid-Crystal Display, Nanocrystal, OLED, Optoelectronics, organic photo detector, organic photovoltaics, perovskite, perovskite devices, perovskite solar cell, photodetection, Solar Cell, X-ray detectors
Category(s): Chemical > Chemical Processing & Manufacturing, Energy & Environment > Energy Efficiency, Energy & Environment, Materials > Composite Materials, Optics & Photonics, Optics & Photonics > Fiber Optics, Materials > Functional Materials
Revolutionizing surgical interventions: the steerable flexible curved-drilling robot (SFCR)
­The Steerable Flexible Curved-Drilling Robot (SFCR) is an innovative medical device designed to enhance precision in surgical drilling through complex bone structures. This cutting-edge technology features a dual-tube system with a flexible drive shaft, enabling controlled, curved drilling paths that navigate around obstacles like nerves and low-density...
Published: 5/23/2025   |   Inventor(s): Farshid Alambeigi, Yang Liu
Keywords(s):  
Category(s): Life sciences > Medical technology > Medical devices
Novel Helical Peptodomimetics that Prevent the Formation of Aβ Oligomerization in Alzheimer’s Disease (AD)
­Advantages: Developed sulfonyl-γ-AA peptide helical peptidomimetics that can prevent the formation of neurotoxic Aβ oligomerization. High Specificity: The lead sulfonyl-γ-AApeptide helical foldamer, Ab-6, exhibits precise targeting to the central region of Aβ42 and induces α-helix conformation in Aβ. Sequence-Specific...
Published: 9/10/2025   |   Inventor(s): Jianfeng Cai, Heng Liu
Keywords(s): Alzheimer's Disease, Biotechnology, Neurodegenerative Diseases
Category(s): Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Medical > Biotechnology, Technology Classifications > Medical > Neuroscience
Intermetallic Fe Based Catalysts for Light Olefin Production
­Advantages: High Selectivity: Up to 45% light olefin selectivity with CO2 included. Exceptional Stability: Maintains performance over a 72-hour run. Customizable Reactivity: Fe:In ratios tune surface composition for optimized olefin production and reduced by-products. Summary: This technology addresses a critical need in the chemical industry...
Published: 8/22/2024   |   Inventor(s): John Kuhn, Babu Joseph, Yang He
Keywords(s): Chemistry and Chemical Engineering, Material Science
Category(s): Technology Classifications > Medical > Biotechnology, Technology Classifications > Chemistry, Technology Classifications > Energy & Environment > Energy Engineering
National Hydrologic Simulation Database
This database includes simulation input and outputs from the ParFlow CONUS 1 and 2 models for use in connection with the HydroGEN system for hydrological modeling. More information on these models can be found at https://hydroframe.org/parflow-conus1 and https://hydroframe.org/parflow-conus2. ParFlow is one of the most physically rigorous hydrologic...
Published: 1/17/2025   |   Inventor(s): Laura Lotter, Andrew Bennett, Amy Johnson, Reed Maxwell, William Hasling, Amy Defnet, Danielle Tijerina, Chen Yang
Keywords(s):  
Category(s): Technology Classifications > Energy, Cleantech & Environmental, Technology Classifications > Software & Information Technology, Technology Classifications > Software & Information Technology > Databases & Data Mining, Technology Classifications > Agriculture & Horticulture
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