Search Results - xun+wang

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Selective estrogen-receptor modulators (SERMs) confer protection against photoreceptor degeneration

Abstract: Retinal degeneration is a deteriorative condition of the human retina caused by the progressive and eventual death of photoreceptor cells. To date, no effective treatment for genetically inherited or age-associated retinal degeneration, which includes a large patient population worldwide, is available. Researchers at the National Eye Institute...

Published: 4/8/2024 | Inventor(s): Wai Wong, Lian Zhao, Xu Wang, Wenxin Ma

Keywords(s): Age-Related Degeneration, AMD, Estrogen-receptor, Microglial Inhibition, National Eye Institute, NEI, Photoreceptor, Retinal degeneration, Retinitis Pigmentosa, RP

Category(s): Application > Therapeutics, Collaboration Sought > Licensing, TherapeuticArea > Opthamology, TherapeuticArea > Eye / Ear / Nose / Throat, Collaboration Sought > Collaboration

Telodendrimer Nanoparticles for Protein Delivery

A nanoparticle-based method for enhanced delivery of protein/peptide therapeutics. Background: Biologics, for example protein and peptide-based therapeutics, have poor in vitro shelf stability and in vivo enzymatic stability, which lead to short blood circulating time and contribute to immunogenicity. In addition, biologics are impermeable to biological...

Published: 7/24/2023 | Inventor(s): Juntao Luo, Xu Wang, Changying Shi, Alexa Bodman, Walter Hall

Keywords(s): cancer therapy, lipidoids, nanoparticles, protein delivery, telodendrimers

Category(s): Campus > Upstate Medical University, Technology Classifications > Drug Delivery, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Materials and Chemicals, Technology Classifications > Nanotechnology

Treating Malaria Using Novel Clinical Drug Candidates that Exhibit Oral Efficacy with Once Daily Dosing

Treating Malaria Using Novel Clinical Drug Candidates that Exhibit Oral Efficacy with Once Daily Dosinghttps://sites.google.com/slu.edu/intellectualproperty/2017/17-036

Published: 1/24/2022 | Inventor(s): Marvin Meyers, Cynthia Dowd, Xu Wang, Robert Brothers, Audrey John, Rachel Edwards

Keywords(s):

Category(s): Therapeutics

3D-Soft Electrode for Li-Chalcogen Batteries

3D-Soft Electrode for Li-Metal Batteries Background Due to their high theoretical current density, Li-Air, Li-sulfur, and Li-selenium batteries have attracted a great deal of attention. Their high energy density, which can be two orders of magnitude greater that current lithium ion batteries, makes them ideal for applications ranging from automotive...

Published: 2/23/2023 | Inventor(s): Hanqing Jiang, Xu Wang, Wei Zeng

Keywords(s): Agriculture and Animal Science, Fuel Cells, Energy, Materials and Electronics

Category(s): Physical Science, Applied Technologies, Energy & Power

Cell Cycle Nucleic Acids, Polypeptides and Uses Thereof - Wee1

This invention improves transformation frequency by changing levels of protein expression in the target cells, altering the cell cycle, specifically by modulating the activity of a gene known as RB3 which influences the cell's progression from G1 to S phase in the cell cycle. Overexpression of RB3 can be induced through existing methods of transient...

Published: 4/3/2023 | Inventor(s): Paolo Sabelli, Yan Liu, Chunsheng Zhang, William Gordon-Kamm, Keith Lowe, Matthew Bailey, Xun Wang, Carolyn Gregory, George Hoerster, John Mcelver, Shane Abbitt, Benjamin Bowen, Brian Larkins, Brian Dilkes, Ricardo Dante, Yeujin Sun

Keywords(s):

Category(s): Technology Classifications > Agriculture & Horticulture, Technology Classifications > Life Sciences, Technology Classifications > Agriculture & Horticulture > Crop Improvement, Technology Classifications > Life Sciences > Therapeutics